1.
J Cell Biol
; 223(6)2024 06 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38669038
RESUMO
Membrane contact sites (MCS) between mitochondria and the nucleus have been recently described. Termed nucleus associated mitochondria (NAM), they prime the expression of genes required for cellular resistance to stressors, thus offering a tethering mechanism for homeostatic communication. Here, we discuss the composition of NAM and their physiological and pathological significance.