Simultaneous Retrieval of Root Fragment, Sinus Lifting With Particulated Bone Graft, and Immediate Dental Implant Insertion.

The aim of these 3 patient reports is to demonstrate a new technique for the reconstruction of the posterior maxilla in patient of a displaced root fragment. The retrieval of root fragments, sinus floor augmentation procedures with a particulated graft, and an implant insertion were performed in the same operation. A simultaneous oro-antral communication was also repaired in 2 patients. Sinus membrane elevations and retrieval of a root fragment via the lateral wall sinus approach were also performed. After repairing a membrane perforation with a particulated graft, an immediate implant insertion was done. An average period of 41 months of clinical and radiographic follow-up revealed a healthy maxillary sinus and a functional implant in the tooth area.

Evaluation of genotoxic and antigenotoxic effects of boron by the somatic mutation and recombination test (SMART) on Drosophila.

OBJECTIVE: In this study, different concentrations of boron have been evaluated for genotoxic and antigenotoxic properties by using the somatic mutation and recombination test (SMART) on Drosophila melanogaster. STUDY DESIGN: The treatment concentrations were chosen to a pretest. Third-instar larvae trans-heterozygous for two genetic markers, multiple wing hair (mwh) and flare (flr3), were treated at different concentrations (0.1, 5, 10, 20, and 40 mg/mL) of boron. In addition to investigating antigenotoxic effects, the same boron concentrations were co-administered with 0.1 mM Ethyl Methane Sulfonate (EMS). Distilled water was used as a negative control; 0.1 mM of EMS was used as a positive control. For the chronic feeding study, small plastic vials were prepared with 1.5 g of dry Drosophila Instant Medium and 5 mL of the respective test solution. Hundreds of trans-heterozygous larvae were embedded into this medium. Feeding ended with pupation of the surviving larvae. After metamorphosis, all surviving flies were collected and stored in a 70% ethanol solution. Preparation and microscopic analyses of wing were made after the treatment. Then the observed mutations were classified according to size and type of mutation per wing. RESULTS: Results indicated that there is no significant genotoxic effect with all of the boron concentrations. In addition, the antigenotoxic activities of boron against EMS were tested. Results indicated that all boron concentrations (0.1, 5, 10, 20 and 40 mg/mL) were able to abolish the genotoxic effects induced by the EMS. CONCLUSION: It is suggested that the observed effects can be linked to the antioxidant properties of boron. Moreover, these in vivo results will contribute to the antigenotoxicity database of boron.

Oxidative imbalance and anxiety in patients with sleep bruxism.

OBJECTIVE: We evaluated the relationship among sleep bruxism (SB), antioxidant/oxidant status, and anxiety level to determine whether antioxidant/oxidant status may be used as a biological marker of SB. STUDY DESIGN: Thirty-three SB and 32 healthy patients of similar age, sex, and body mass index were enrolled, venous blood was collected, and anxiety scores were determined. Plasma samples were analyzed for total oxidant status, antioxidant status, and oxidative stress index. RESULTS: In 2 of the 3 assays performed, SB patients exhibited an oxidative imbalance. A higher anxiety score was observed with SB (P < 0.05). CONCLUSIONS: These results show that oxidant/antioxidant imbalance may be related to SB, either pathophysiologically or as an outcome of the condition. Further biochemical studies could prove useful in determining the importance of antioxidant drugs in the treatment of SB.

Effects of Ginkgo biloba on experimental rapid maxillary expansion model: a histomorphometric study.

OBJECTIVE: We aimed to investigate the effect of systemic Ginkgo biloba in rapid maxillary expansion (RME). STUDY DESIGN: We randomly divided 24 rats into 3 groups: expansion only (EO), expansion plus Ginkgo biloba (GB), and no expansion (NE). Expansion appliances were affixed to the maxillary incisors. After a 5-day expansion period, there was a consolidation period of 15 days, following which the rats were killed. Histomorphometric examination was performed to determine the number of osteoclasts, osteoblasts, and capillaries, the number and intensity of inflammatory cells, and new bone formation. RESULTS: New bone formation, number of capillaries, and the ratio of inflammatory cells in maxillary sutures were higher in the GB group than in the other groups. Statistical analysis demonstrated that the GB group had more osteoblasts and osteoclasts than the other groups. CONCLUSIONS: GB may hasten new bone regeneration in RME and prevent relapse after RME.

Mandibular mucormycosis in immunocompromised patients: report of 2 cases and review of the literature.

Mucormycosis, also known as zygomycosis, is an opportunistic fungal infection caused by a series of fungi in the Mucorales family in people with immune disorders. It is harmless to a healthy person, but when it has invaded the internal organs, it is frequently fatal in immunocompromised patients. It is known for having a very poor prognosis; however, with aggressive medical and surgical management, survival rates are currently thought to exceed 80%. It has 7 predominant clinical forms: rhinocerebral, pulmonary, cutaneous, gastrointestinal, central nervous system, disseminated, and, rarely, miscellaneous (ie, bone, kidney, cardiac, mediastinum, oral). Although oral involvement of this condition has been reported relatively frequently in the literature, mandibular involvement is a rarer condition than oral involvement. The purpose of this article is to report the treatment of isolated cases of mandibular mucormycosis and a review of the literature.

Characteristics of 351 supernumerary molar teeth in Turkish population.

OBJECTIVE: The aim of the present study was to evaluate the demographic profile of supernumerary molar (SM) teeth in people in various regions of Turkey. STUDY DESIGN: A retrospective analysis was carried out on an initial sample of 104,902 subjects drawn from the ortopantographics files from 10 clinics in 7 Turkish cities with documentation of demographic data, the presence of SM teeth, their location, eruption, morphology, and position within the arch. In one region associated patho-logies and treatments were also evaluated. RESULTS: Three hundred fifty-one SMs were detected in 288 patients, constituting 0.33% of the study subjects, with a greater frequency in females (56.4%). SMs were found more frequently in the maxilla (87.7%) than in the mandible, and distomolars (62.9%) were more common than paramolars. The SMs encountered were mostly of conical shape (45.7%), impacted (81.1%), and in a vertical position (52.1). The 33% of SM teeth were related to impacted molar teeth. CONCLUSION: The most common complication involving these teeth was soft tissue irritation. Demographic data from such specific extensive studies are crucial for improved diagnosis of SM teeth. Early detection allows for measures against complications and more successful therapy.

Analysis of different type of transmigrant mandibular teeth.

OBJECTIVE: Until recently, most reports about transmigration have documented that the canine is the only tooth which can migrate to the opposite side of the arch. The goal of the study was to define the transmigration of different types of teeth in people in various regions of Turkey. STUDY DESIGN: A total of 112,873 panoramic radiographic files from seven different Turkish cities were inspected. The following data were evaluated according to age, gender, number of transmigrant teeth, localization, eruption status, side, unilaterally or bilaterally and associated pathology or dental abnormalities. RESULTS: Of the 112,873 radiographs included in the study, 90 were seen to present as transmigrant in 87 patients, representing 0.079% of the sample. There were only two (0.0017%) transmigrant lateral (TML) teeth and only three (0.0026%) transmigrant premolar (TMP) teeth encountered. The mean age at the time that the transmigrant mandibular teeth were identified was 29.9 years, with a range from 10 to 66 years. Out of the 87 cases, 51 were female and 36 were male, with a male:female ratio of 1:1.41. Transmigrants were more commonly seen unilaterally (96.5%). The most frequent associated pathology was odontoma. CONCLUSIONS: Because early detection is vital to prevent complications and ensure more successful treatment, these extensive studies are crucial. In this extensive study, we indicated cases of transmigration of premolar and lateral teeth as a variant. Demographic variables and properties of all transmigrants (TM) were also presented.

Neoplasms of the salivary glands in a Turkish adult population.

OBJECTIVE: This retrospective study aimed to investigate the types and distribution of neoplasm of salivary glands in a Turkish population. STUDY DESIGN: The histological diagnosis records of the Department of Pathology at Cumhuriyet University were reevaluated for 125 patients who were treated for salivary gland tumors from 1987 to 2008. The neoplasms were analyzed for histological diagnosis, age, sex, and site. The histological diagnoses were analyzed according to the 2005 WHO classification. RESULTS: A total of 125 primary salivary gland neoplasms, consisting of 95 (76%) benign and 30 (24%) malignant groups were recorded. The most common major and minor salivary gland sites were the parotid (61.6%) and palatal glands (9.6%), respectively. Pleomorphic adenoma was the most frequent benign tumor followed by Warthin's tumor. Among the malignant group, adenoid cystic carcinoma was the most prevalent. Age for all cases ranged from 16-80 years; mean age was 41.97 years, with a female to male ratio of 1:1.15. CONCLUSIONS: Although there were some discrepancies, the characteristics of salivary gland tumors of Turkish patients are in line with those of patients from other countries according to tumor type, tumor site distribution, and age and sex of patients.