Dataset on extreme thunderstorm ground enhancements registered on Aragats in 2023.

To advance high-energy atmospheric physics, studying atmospheric electric fields (AEF) and cosmic ray fluxes as an interconnected system is crucial. At Mt. Argats, simultaneous measurements of particle fluxes, electric fields, weather conditions, and lightning locations have significantly enhanced the validation of models that describe the charge structures of thunderclouds and the mechanics of internal electron accelerators. In 2023, observations of the five largest thunderstorm ground enhancements (TGEs) revealed electric fields exceeding 2.0 kV/cm at elevations just tens of meters above ground-potentially hazardous to rockets and aircraft during launch and charging operations. Utilizing simple yet effective monitoring equipment developed at Aragats, we can mitigate the risks posed by these high-intensity fields. The Mendeley dataset, comprising various measured parameters during thunderstorm activities, enables researchers to perform advanced correlation analysis and uncover complex relationships between these atmospheric phenomena. This study underscores the critical importance of integrated atmospheric studies for ensuring the safety of high-altitude operations and advancing atmospheric science.

[The present-day medical demographic situation in the Republic of Karelia].

The analysis of basic medical and demographic indicators (primary morbidity and disability of adult population, mortality, age structure and life expectancy) and provision of medical care in the Republic of Karelia in 2011-2020 was carried out. It established consistently high level of primary morbidity of population with respiratory diseases; injuries, poisoning and other consequences of external causes; diseases of genitourinary system. Diseases of cardiovascular system and malignant neoplasms occupy leading positions in the structure of causes of disability and mortality of population during period under review. The levels of primary morbidity, disability and mortality of the Republic population are higher than at national level. The age structure of population has regressive type, there is long-term process of demographic aging, life expectancy is gradually increasing. Since 2011, the number of out-patient clinics increased up to 3 times and their capacity increased too. The degree of provision of population with medical personnel remained stable for a decade. The number of secondary medical personnel is decreasing, while both indicators are higher than the national indocators.

[The nature of the actual nutrition of elderly residents of the European North of Russia who had community-acquired pneumonia, not associated with the COVID-19 virus, from the standpoint of the possibility of the microelement state disorder.]

An increasing number of elderly and senile people characterises the structure of modern society. With ageing, a violation of the microelement homeostasis of the human body occurs. The natural biogeochemical conditions of the North initiate a metabolic restructuring of the body, accompanied by changes in the microelement state, which disrupts the functions of protective systems and increases the risk of developing diseases. The purpose of the study is to investigate the possibility of developing a mineral metabolism disorder in elderly and senile people who have suffered community-acquired pneumonia, not associated with the COVID-19 virus, due to the nutritional habits in the Republic of Karelia. The assessment of food rations and the study of the awareness of healthy nutrition of these individuals were carried out, according to a specially designed questionnaire. Of the 100 questionnaires distributed, 89 suitable for analysis were studied, taking into account the gender of the respondents. As a result of the study, it was demonstrated that the nutrition of elderly and senile people cannot meet the body's needs for trace elements due to insufficient consumption of vegetables and fruits, dairy and meat products, and fish.

Excess mortality after hip fracture in elderly persons from Europe and the USA: the CHANCES project.

BACKGROUND: Hip fractures are associated with diminished quality of life and survival especially amongst the elderly. OBJECTIVE: All-cause mortality after hip fracture was investigated to assess its magnitude. METHODS: A total of 122 808 participants from eight cohorts in Europe and the USA were followed up for a mean of 12.6 years, accumulating 4273 incident hip fractures and 27 999 deaths. Incident hip fractures were assessed through telephone interviews/questionnaires or national inpatient/fracture registries, and causes of death were verified with death certificates. Cox proportional hazards models and the time-dependent variable methodology were used to assess the association between hip fracture and mortality and its magnitude at different time intervals after the injury in each cohort. We obtained the effect estimates through a random-effects meta-analysis. RESULTS: Hip fracture was positively associated with increased all-cause mortality; the hazard ratio (HR) in the fully adjusted model was 2.12, 95% confidence interval (CI) 1.76-2.57, after adjusting for potential confounders. This association was stronger amongst men [HR: 2.39, 95% CI: 1.72-3.31] than amongst women [HR: 1.92, 95% CI: 1.54-2.39], although this difference was not significant. Mortality was higher during the first year after the hip fracture [HR: 2.78, 95% CI: 2.12-3.64], but it remained elevated without major fluctuations after longer time since hip fracture [HR (95% CI): 1.89 (1.50-2.37) after 1-4 years; 2.15 (1.81-2.55) after 4-8 years; 1.79 (1.57-2.05) after 8 or more years]. CONCLUSION: In this large population-based sample of older persons across eight cohorts, hip fracture was associated with excess short- and long-term all-cause mortality in both sexes.

Role of innate immunity in pregnant patients with vulvovaginal infections in the development of intrauterine infection in the newborn.

A total of 115 pregnant women were examined: 59 patients with opportunistic vulvovaginal infections and 56 without infection. Congenital immunity parameters (TLR-2, NF-κB, and IL-2 receptors in placental tissue) were studied by immunohistochemical methods. Realization of congenital infection was associated with activation of IL-6 receptors and TLR-2 in the placenta and an increase of NF-κB level. These changes seemed to reflect the strained status of congenital immunity and were responsible for the intensity of local inflammatory response.