RESUMO
Granular parakeratosis is an acquired, idiopathic disorder of keratinization typified by retention hyperkeratosis. It usually occurs in women at intertriginous sites. There have been only 2 reports of infants with granular parakeratosis to our knowledge. We describe 3 additional infants with granular parakeratosis. We demonstrate that infantile granular parakeratosis exhibits 2 clinical patterns: bilateral linear plaques in the inguinal folds; and erythematous geometric plaques underlying pressure points from the diaper. A thick, flakelike scale is present in both forms and is characteristic. Diaper wearing appears to play an important role in the genesis of infantile granular parakeratosis but the mechanisms are unclear. Therapeutic responsiveness to topical agents is ambiguous, however, spontaneous clearance after months to 1 year appears to be the rule.
Assuntos
Paraceratose/diagnóstico , Pele/patologia , Biópsia , Diagnóstico Diferencial , Dermatite das Fraldas/diagnóstico , Fraldas Infantis , Feminino , Virilha , Humanos , Lactente , Masculino , Paraceratose/etiologia , Paraceratose/patologiaAssuntos
Dermatite de Contato/etiologia , Urticária/induzido quimicamente , Alérgenos/efeitos adversos , Anestésicos Locais/efeitos adversos , Anti-Infecciosos Locais/efeitos adversos , Bandagens/efeitos adversos , Toxinas Botulínicas Tipo A/efeitos adversos , Colágeno/efeitos adversos , Fármacos Dermatológicos/efeitos adversos , Detergentes/efeitos adversos , Humanos , Hipersensibilidade/etiologia , Hipersensibilidade ao Látex/induzido quimicamente , Resina Mástique , Extratos Vegetais/efeitos adversos , Resinas Vegetais/efeitos adversos , Styrax , Cirurgia Plástica , Adesivos Teciduais/efeitos adversos , Urticária/imunologiaRESUMO
Initial symptoms of Rocky Mountain spotted fever (RMSF), a tick-borne illness caused by Rickettsia rickettsii, are nonspecific and include headache, gastrointestinal disturbances, malaise, and myalgias, followed by fever and rash. The classic triad of fever, rash, and history of tick exposure is uncommon at presentation. Clinical manifestations of RMSF range from virtually asymptomatic to severe. Because of the potentially fatal outcome of RMSF, presumptive clinical diagnosis and empiric antimicrobial therapy can be critical. We present the case of a 3-year-old girl from New York State who presented with fever and rash.
Assuntos
Doxiciclina/administração & dosagem , Febre Maculosa das Montanhas Rochosas/diagnóstico , Febre Maculosa das Montanhas Rochosas/tratamento farmacológico , Pré-Escolar , Relação Dose-Resposta a Droga , Esquema de Medicação , Exantema/diagnóstico , Feminino , Febre/diagnóstico , Seguimentos , Humanos , Medição de Risco , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
A case is presented of a 55-year old woman who developed an eruption suggestive of contact dermatitis on repeated occasions after receiving anesthesia for dermatologic procedures. Patch testing revealed a positive reaction to lidocaine. Basic structures of anesthetics are reviewed, and the classification of immunologically-mediated allergic reactions is discussed. The presence of cutaneous lidocaine allergy has profound implications for the field of dermatology.