RESUMO
The Earth's climate is influenced by both natural phenomena (solar fluctuations, oceanic patterns, volcanic eruptions, and tectonic movements) and human activities (deforestation, CO and CO2 emissions, and desertification), all of which contribute to ongoing climate change and the resulting global warming. However, human actions are a major factor in exacerbating global warming and amplifying its adverse impacts worldwide. . With rising temperatures, water evaporation from water bodies and soils intensifies, leading to heightened water scarcity, particularly in drought-prone regions. This scarcity compounds rainfall deficits, posing significant challenges. Precipitation, essential for the biosphere's hydrological cycle, replenishes much of the world's freshwater. It occurs when condensed water vapor in the atmosphere falls back to Earth as rain, drizzle, sleet, graupel, hail, or snow due to gravity. Literature highlights the indispensable role of bacterial populations in this process, termed bio-precipitation. This phenomenon begins with bacterial colonization on plant surfaces, with colonies subsequently dispersed into the atmosphere by winds, triggering ice crystal formation. Through their ice nucleating property, these bacteria facilitate the growth of larger ice crystals, which eventually melt and precipitate as rain or snow. This mechanism aids in nutrient transfer from clouds to soil or vegetation. Pseudomonas syringae stands out as the most notable microorganism exhibiting this ice-nucleation property, serving as the primary source of ice nucleators driving bio-precipitation. Despite limited literature on "rain and snow-causing bacteria," this review comprehensively explores the conceptual background of bio-precipitation, the involved bioprocesses, and the critical role of bacteria like P. syringae, offering insights into future research directions.
RESUMO
Coronaviruses hold idiosyncratic morphological features and functionality. The members of this group have a remarkable capability of infecting both animals and humans. Inimitably, the replication of the RNA genome continues through the set of viral mRNA molecules. Coronaviruses received least attention until 2003 since they caused only minor respiratory tract illnesses. However, this changed exclusively with the introduction of zoonotic SARS-CoV in 2003. In 2012, MERS-CoV emerged and confirmed this group of viruses as the major causative agents of severe respiratory tract illness. Today, Coronavirus Disease 2019 (i.e., COVID-19) has turned out to be a chief health problem that causes a severe acute respiratory disorder in humans. Since the first identification of COVID-19 in December 2019 in Wuhan, China, this infection has devastatingly spread all around the globe leading to a crippling affliction for humans. The strain is known as the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and WHO (the World Health Organization) has termed this new pandemic disease as Coronavirus Disease (COVID-19). COVID-19 is still spreading, with an estimated 136 million confirmed cases and more than 2.94 million deaths worldwide so far. In the current scenario, there is no particular treatment for COVID-19; however, remarkable efforts for immunization and vaccine development can be observed. Therefore, the execution of precautions and proper preventive measures are indispensable to minimize and control the community transmission of the virus. This review summarizes information related to the pathophysiology, transmission, symptoms, the host defense mechanism plus immunization and vaccine development against COVID-19 including the patents filed.