3D-based strain analysis and cardiotoxicity detection in cancer patients received chemotherapy.

BACKGROUND: Chemotherapy-induced cardiotoxicity has become a prevalent complication. Regular monitoring of patients who received chemotherapy using 3D strain parameters may aid in early detection of myocardial damage and its prevention. The purpose of this study was to evaluate the effectiveness of three-dimensional speckle tracking imaging (3D-STI) in diagnosing and predicting the likelihood of cardiotoxicity. This was achieved by conducting a systematic review of original research articles. OBJECTIVES: To evaluate the role of 3D speckle tracking echocardiography in early detection of cardiotoxicity. METHODS: Relevant case control studies published prior to December 2022 were extracted to assess cardiotoxicity by 3D STE in patients after chemotherapy. RESULTS: A total of 1991 chemotherapy treated patients and control patients were included in the present review via pooling 22 studies. CONCLUSIONS: 3D speckle tracking echocardiography has the utility of non-invasive and objective evaluation of changes in left ventricular function in cancer patients undergoing chemotherapy. ROSPERO REGISTRATION NO: Study ID, CRD42023383790 on PROSPERO: International prospective register of systematic reviews.

Effect of using Austrian pine cones powder as an additive on oil well cement properties.

There have been many investigations to improve both the physical and mechanical properties of oil well cement using a wide range of materials. Most of these additives are expensive and practically ineffective. In this article, a comprehensive evaluation was conducted for using Austrian pinecones powder (APCP) as an inexpensive supplementary cementing material (SCM) for well cement. Firstly, Portland cement class G was characterized based on X-Ray Fluorescence (XRF), X-Ray Diffraction (XRD). In this paper, the properties of the cement systems include rheological parameters, density, slurry stability (free water test, and sedimentation test), water absorption, porosity, permeability, the volume of fluid loss, pH value, thermogravimetric analysis, and the mechanical characteristics (in terms of compressive strength, tensile strength, flexural strength, and shear strength bond) were investigated in details. The cement sample containing the APCP was also examined using scanning electron microscopy (SEM). According to the experimental results, adding APCP led to increasing in rheological parameters. Also, led to decreasing in fluid loss, free water, sedimentation effect, and density which positively affects the preservation of the original properties of cement slurry. The results also showed a decrease in the permeability of cement samples and an increase in the porosity and the ability to absorb water. The addition of APCP did not significantly affect the pH values. The addition of APCP also deteriorated the mechanical properties of the cement samples. The addition of the APCP has contributed to an increase in total weight loss at high temperatures. So, the APCP can be considered as a new filler for well cement due to its ability to fill the pores in the cement matrix and at the same time improve some properties of the well cement such as density, free water, sedimentation, and fluid loss.

Association of Flying Time with Hearing Loss in Military Pilots.

BACKGROUND: Military pilots are exposed to harmful noise levels, and the two possible effects of this are hearing loss and tinnitus. OBJECTIVE: This study was conducted to determine the prevalence of noise-induced hearing loss among Saudi military pilots and to determine its association with total flight hours and aircraft type (i.e., fixed and rotary wing). MATERIALS AND METHODS: This cross-sectional study was conducted at the Armed Forces Aeromedical Centre, Dhahran, Saudi Arabia, between November 2015 and October 2016. A total of 150 Saudi military pilots were interviewed using a structured questionnaire. Pure-tone audiometry was used to measure hearing thresholds. Hearing threshold levels were compared between age groups and aircraft category. The association between total flying hours and the development of noise-induced hearing loss was analyzed. RESULTS: The overall prevalence of noise-induced hearing loss in the military pilots was 18.4%, with a higher prevalence among fixed-wing pilots (42%) as compared with rotary-wing pilots (23%). Pilots with ≥2000 flying hours had a significantly higher hearing threshold compared with those in other categories. Age was a statistically significant risk factor. CONCLUSIONS: This study found that active pilots of both fixed- and rotary-wing aircrafts are at a high risk of noise-induced hearing loss; however, fixed-wing pilots with ≥2000 flying hours are at a higher risk. These findings support recommendations requiring instructions on the proper use of hearing protection devices to avoid noise-induced hearing loss.

Too little appreciation for great expenditure? Workload and resources in ICUs.

PURPOSE: The aim of this study was providing descriptive information and the comparative examination of job strain and mental health of nurses and physicians in different intensive care units (ICU). METHODS: The Effort-Reward Imbalance Questionnaire by Siegrist and standardized psychometric questionnaires, like Hospital Anxiety and Depression Scale, Impact of Event Scale, Brief Symptom Inventory, Social Support Questionnaire, and Life Satisfaction Questionnaire were used. Five ICUs of the same German medical school were included (N = 142). RESULTS: For all ICUs investigated, a significantly lower mental health and a high effort-reward imbalance were found when compared with other samples. Only a few differences between the wards or both professional groups (nurses vs. physicians) were noted. The values for social support were comparable with those of healthy controls but differed between the wards. The life satisfaction in our cohort was lower compared to a population-based sample but was significant different between the wards. CONCLUSIONS: Our study demonstrates the high job strain in an ICU, largely independent of the professional group. Noteworthy, a high effort-reward imbalance was found that stands in positive relation to adverse health effects (anxiety, depression, and general mental health). As a consequence, necessary interventions like stress management, supervision, and communication trainings should consider ward-specific conditions of employment rather than professional affiliation. After these interventions, a follow-up study will be performed to examine beneficial effects on job strain and health.