Geospatial quality assessment of locally available ice for heavy metals and metalloids and their potential risks for human health in Karachi, Pakistan.

Extreme hot conditions during summers, high poverty rate and continuous electricity load shedding affect commercial manufacturing and sale of ice in many countries. The vendors prepared ice using untreated piped water, tanker water and ground water. These waters may contain hazardous pollutants and ice made from them will pose a potential human health risk. Thus, it is important to regularly monitor the chemical composition of water sources and the quality of the manufactured ice. A contemporary examination was carried out to evaluate the physico-chemical properties and heavy metals and metalloids in the ice sold in all the districts of Karachi, Pakistan. This pioneering study was an innovative effort to assess the ice quality in relation to potential pollutant hazards to human health; with concomitant geospatial information. The geospatial distribution of ice quality and major constituents were among the measured parameters; carefully associated with further geospatial information, determined using GIS (Geographic Information Systems) and PCA (Principal Component Analysis) techniques. Interestingly, the physico-chemical analyses revealed that the ice quality was marginally adequate and the total mean metal-metalloid contents were in the sequence of Pb > Ni > Zn > Fe > Cr > As. The concentrations of these metals were above the upper allowable limits with reference to the recommended WHO guidelines. We observed that 57.1% and 35.7% ice samples had good physico-chemical properties assessed using the Ice Quality Index (IQI). Conversely, the IQI for metals showed that the ice was unsafe for human consumption. In terms of health risk assessment, the overall mean CDI (Chronic Daily Intake) and HQ (Hazard Quotient) values were in the order of Pb () > Ni (3.2) > Zn (2.3) > Fe (2.1) > Cr (1.6) > As (0.5) and Pb (7.4) > As (1.7) > Cr (0.5) > Ni (0.4 > Zn (0.008) > Fe (0.003), respectively. This study highlighted that routine monitoring of the water supplies available for making ice is required to protect public health.

Impact of domestic and industrial effluent on marine environment at Karachi Port Trust (KPT) coastal area, Pakistan.

The extent of aquatic pollution of Karachi Port Trust (KPT) coastal area located at the south of Pakistan coast has increased considerably in the last few decades due to unrestricted discharge of sanitary waste. The current study lays emphasis on the identification of vulnerable zones severely impacted by pollution in the KPT coastal area using laboratory monitoring, geospatial techniques, and statistical analysis. During 2019, sampling was conducted along the KPT coastal area, and 54 samples of seawater were collected during pre- and post-monsoon seasons. The outcomes of physical and chemical analysis revealed that the concentrations of BOD (biochemical oxygen demand), COD (chemical oxygen demand), nitrate, phosphate, phenol, cyanide, and oil and grease frequently exceeded the permitted limit of international norms and reached much greater levels. The levels of perilous metals in the seawater samples were in the order Ni>Cr>Cu>Pb>Cd>As in both phases and also reached to elevated levels as a consequence of the indiscriminate discharge of untreated industrial and domestic wastewater. Based on detailed examination during pre- and post-monsoon, six sites near KPT, Lyari River outfall, and Karachi Harbour were identified as highly polluted zones due to heavy discharge of sanitary effluents at these sites. In particular, the industrial zones present in the formal and informal sectors of Karachi are responsible for the deterioration of the KPT coastal area. Therefore, it is advised to design and build a submerged drainage system to transport and distribute massive amounts of treated municipal and industrial waste to the deep open sea in order to minimize the high pollutant levels in these locations.

Evaluating dual exposure by using climate-conflict vulnerability index on the coastal districts of Sindh, Pakistan.

Climate variability is widely recognized as a major concern, particularly in resource-scarce regions where it limits livelihood opportunities by putting additional strain on already depleting resources, resulting in human insecurity and conflicts. Some vulnerability assessments have created a nexus between climate variability and conflicts. The Climate-Water Conflict Vulnerability Index (CWCVI) and the Climate-Agriculture Conflict Vulnerability Index (CACVI) are applied as a tool for exploring the climate and conflict interactions, as well as contrasting the vulnerabilities of the coastal districts of Badin, Thatta, and Sujawal. The analysis incorporates a dual exposure of communities in the form of climate variability and conflict over water and agricultural resources. The study finds that aggression and feelings of insecurity about depleting resources are the main contributing indicators of climate-conflict vulnerability in the coastal districts. District Sujawal showed higher vulnerability in adaptive capacity as compared to the other districts due to poor infrastructure and high dependency on natural resources. However, the district of Badin demonstrated high vulnerability in terms of sensitivity and its exposure to conflicts over agricultural resources is high. The overall CWCVI and CACVI scores were higher in Badin and Thatta, respectively. This study identifies a number of indicators that can be used to improve the efficacy of mitigation strategies to reduce conflict vulnerability in future policy directions and resource planning.

Geospatial assessment of water quality using principal components analysis (PCA) and water quality index (WQI) in Basho Valley, Gilgit Baltistan (Northern Areas of Pakistan).

Public health quality in Gilgit Baltistan (GB) is at threat due to multiple water-borne diseases. Anthropogenic activities are accelerating the burden of pollution load on the glacio-fluvial streams and surface water resources of Basho Valley in Skardu district of GB. The present research has investigated the drinking water quality of the Basho Valley that is being used for domestic purposes. The study also comprehends public health status by addressing the basis drinking water quality parameters. A total of 23 water samples were collected and then analyzed to elucidate the current status of physico-chemical, metals, and microbial parameters. Principal component analysis (PCA) was applied and three principal components were obtained accounting 53.04% of the total variance, altogether. PCA identified that metallic and microbial parameters are the major factor to influence the water quality of the valley. Meanwhile, water quality index (WQI) was also computed and it was observed that WQI of the valley is characterized as excellent in terms of physico-chemical characteristics; however, metals and microbial WQI shows most of the samples are unfit for drinking purpose. Spatial distribution is also interpolated using the Inverse distance weight (IDW) to anticipate the results of mean values of parameters and WQI scores. The study concludes that water quality is satisfactory in terms of physico-chemical characteristics; however, analysis of metals shows that the concentrations of copper (Cu) (0.40 ± 0.16 mg/L), lead (Pb) (0.24 ± 0.10 mg/L), zinc (Zn) (6.77 ± 27.1 mg/L), manganese (Mn) (0.19 ± 0.05), and molybdenum (Mo) (0.07 ± 0.02 mg/L) are exceeding the maximum permissible limit as set in the WHO guidelines for drinking water. Similarly, the results of the microbial analysis indicate that the water samples are heavily contaminated with fecal pollution (TCC, TFC, and TFS > 3 MPN/100 mL). On the basis of PCA, WQI, and IDW, the main sources of pollution are most likely to be concluded as the anthropogenic activities including incoming pollution load from upstream channels. A few underlying sources by natural process of weathering and erosion may also cause release of metals in surface and groundwater. This study recommends ensuring public health with regular monitoring and assessment of water resources in the valley.

Addressing COVID-19 contagion through the HVAC systems by reviewing indoor airborne nature of infectious microbes: Will an innovative air recirculation concept provide a practical solution?

As the world continues to grapple with the reality of coronavirus disease, global research communities are racing to develop practical solutions to adjust to the new challenges. One such challenge is the control of indoor air quality in the COVID-19 era and beyond. Since COVID-19 became a global pandemic, the "super spread" of the virus has continued to amaze policymakers despite measures put in place by public health officials to sensitize the general public on the need for social distancing, personal hygiene, etc. In this work, we have reviewed the literature to demonstrate, by investigating the historical and present circumstances, that indoor spread of infectious diseases may be assisted by the conditions of the HVAC systems. While little consideration has been given to the possibility of indoor airborne transmission of the virus, the available reports have demonstrated that the virus, with average aerodynamic diameter up to 80-120 nm, is viable as aerosol in indoor atmosphere for more than 3 h, and its spread may be assisted by the HVAC systems. Having reviewed the vulnerability of the conventional ventilation systems, we recommend innovative air circulation concept supported by the use of UVGI in combination with nanoporous air filter to combat the spread of SARS-CoV-2 and other harmful microbes in enclosed spaces.

A comparative study on degradation of complex malathion organophosphate using of Escherichia coli IES-02 and a novel carboxylesterase.

Malathion organophosphates considered as the major constituent of herbicides, pesticides and insecticides. Extensively used in agricultural, horticultures and for numerous household applications contributes to precedence organic pollutants leading antagonistic effects on human health and environment. Therefore detoxification of malathion from contaminated site is of general interest. Simultaneously it is very emerging to isolated novel indigenous microbial strains from contaminated site with a record of pesticide application. In this study Escherichia coli IES-02 isolated from malathion contaminant effluent and the strain showed maximum efficiency in malathion degradation that utilized it as the sole source of carbon. Carboxylesterase (33.0, 30.0, 28.0 kDa) were purified (1685.71 U/mg) from Escherichia coli IES-02 showed significant results in malathion degradation approximately 81% within 20 min as compared with Escherichia coli IES-02 cells within 4 h (99.0 to 95.0%) into monocarboxylic acid and diacid derivatives. The generation time of Escherichia coli was also observed at 60 min with 0.1 ppm, 68 min with 0.5 ppm, 74.5 min with 2.0 ppm and 91.37 min with 50 ppm of malathion. The degradation rate and transformation metabolites were estimated by Gas Chromatography-Mass Spectrometry respectively. Malathion metabolites pathway proposed in this study which revealed the potential application against lethal environmental pollution.

Assessment of groundwater quality in the coastal area of Sindh province, Pakistan.

Groundwater is a highly important resource, especially for human consumption and agricultural production. This study offers an assessment of groundwater quality in the coastal areas of Sindh province in Pakistan. Fifty-six samples of groundwater were taken at depths ranging from 30 to 50 m. Bacteriological and physico-chemical analyses were performed using the Standard Methods for the Examination of Water and Wastewater. These were supplemented with expert interviews and observations to identify the usage of water and potential sources of pollution. The quality of the groundwater was found to be unsuitable for human consumption, despite being used for this purpose. The concentrations of sulfate and phosphate were well within the tolerance limits. Most critical were the high levels of organic and fecal pollution followed by turbidity and salinity. Metal concentrations (As, Ca, Cr, Cu, Fe, Mg, Mn, Ni, Pb, and Zn) were also determined, and Ni and Pb strongly exceeded health standards. The study stresses the need for significant improvements of the irrigation, sanitation, and sewage infrastructure.

Patterns And Determinants Of Breast Feeding Among Mother Infant Pairs In Dera Ghazi Khan, Pakistan.

BACKGROUND: Proper breastfeeding practices are effective ways for reducing childhood morbidity and mortality. The objective of the present study was to determine the patterns and explore the determinants associated with breast feeding practices among the nursing women in Dera Ghazi Khan. METHODS: A cross sectional study was conducted on randomly selected lactating mother infant pairs in Dera Ghazi Khan. Structured questionnaire was used for data collection. Analysis was done by using SPSS, chi square test was applied to see the association between breast feeding practices and its determinants such as knowledge of breast feeding practices. RESULTS: Majority 372 (93%) of mothers mentioned that they had ever breastfed the youngest child. About 292 (73%) mothers gave colostrum to the child, and 48 (12%) exclusively breastfed. Weaning babies before four month of age was practiced by 84 (21%) of the mothers, 120 (55%) mothers started weaning at 4-6 months of child age, while 72 (18%) started to give additional food after baby turned six months old. Out of total 276 (69%) mothers reported that they had knowledge regarding breast feeding. Significant association was found between knowledge of breastfeeding and initiation and Exclusive Breast Feeding (EBF) practices (p-values <0.05). Income, family type, mode of delivery and assistance for child were significantly associated with initiation of breastfeeding within one hour after birth (p-value <0.001). CONCLUSIONS: Breast feeding practices in the studied area were not up to the mark. There is a strong need to improve the breastfeeding practices by Behavior Change Communication.