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1.
Chirurg ; 92(12): 1114-1122, 2021 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-33599806

RESUMO

BACKGROUND: There are few data on how surgeons implement occupational safety measures to protect their own health and how they assess their subjective health burden. OBJECTIVE: In times of a shortage of surgeons it makes sense to examine these relationships in order to evaluate future-oriented adjustments to increase the attractiveness of the profession of "surgeon". MATERIAL AND METHODS: An online questionnaire was sent to the registered members of the German Society for General and Visceral Surgery (DGAV) in October 2016. The members were asked about the application of occupational safety measures, individual living conditions, working conditions and the subjective health burden depending on the level of training and type of hospital (basic, standard, maximum care). RESULTS: The response rate was 21% (1065/5011). Occupational safety measures were not strictly implemented: routine use of dosimeters, thyroid radiation protection, smoke extraction and protective goggles only took place in 40% (427/1065), 39% (411/1065), 10% (104/1065) and 5% (55/1065), respectively. The majority of surgeons (51%, 548/1065) rated their lifestyle as unhealthy. The majority of them are senior physicians, 46% (250/548) consider their job to be a health hazard. The proportion of chief physicians and assistant physicians is only 21% (115/548) and 18% (98/548). CONCLUSION: Guidelines for standardizing the perioperative protection of German surgeons are desirable. Health-promoting behavior could have a positive effect on the occupational safety of surgeons and ultimately also on patient safety. This can contribute to increasing the attractiveness of the profession "surgeon" in the long term.


Assuntos
Saúde Ocupacional , Cirurgiões , Alemanha , Humanos , Segurança do Paciente , Inquéritos e Questionários
2.
Ann Anat ; 232: 151560, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32565392

RESUMO

INTRODUCTION: Peptic ulcers account for 50% of upper gastrointestinal bleeding incidents. Bleedings from large vessels, such as the gastroduodenal artery, are associated with increased mortality. Ulcers located on the posterior wall of the duodenum show the highest risk for erosion of the gastroduodenal artery. Endoscopic management is challenging and rebleeding rates are high due to internal and external confounding factors such as anatomical variability and gastric insufflation. We aimed to correlate macroscopic and endoscopic anatomy for assessment of implications for clinical management. MATERIAL AND METHODS: The gastroduodenal artery was dissected in 10 anatomical specimens. The points of contact of the artery with the posterior wall of the duodenum were marked with needles. The endoluminal position of the needles was recorded by standardized gastroscopy and a 3-dimensional virtual reconstruction was carried out for visualization of the artery's course. RESULTS: The artery's proximal and distal points of contact with the duodenum were 27.2mm (range 15-30mm; SD 6.7mm) and 15mm (range 10-20mm; SD 3.5mm), respectively, from the pylorus. The gastroduodenal artery branches from the common hepatic artery within the omentum minus running adjacent to the duodenal wall to the head of the pancreas. From endoscopic perspective, the gastroduodenal artery's course was directed towards the tip of the gastroscope. CONCLUSION: Due to the peculiar extraluminal course of the gastroduodenal artery the arterial blood flow projects into the direction of the gastroscope during endoscopic intervention. Measures for bleeding control might have to be applied aboral from the bleeding site.


Assuntos
Artérias/anatomia & histologia , Duodeno/irrigação sanguínea , Hemorragia Gastrointestinal/terapia , Estômago/irrigação sanguínea , Idoso , Idoso de 80 Anos ou mais , Endoscopia Gastrointestinal , Feminino , Humanos , Masculino
3.
Br J Surg ; 105(6): 645-649, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29579320

RESUMO

BACKGROUND: Suturing the platysma muscle during wound closure after thyroid surgery is frequently described in the literature. There is no prospective evidence to support its use or benefit. The aim of this study was to evaluate how a platysma muscle suture influences initial postoperative pain following thyroid surgery. METHODS: Patients were assigned randomly to receive a platysma suture or no platysma suture in this prospective, patient-blinded trial. The duration of follow-up was 6 months. The primary endpoint was wound-specific pain 24 h after thyroid resection. Secondary endpoints were intraoperative and perioperative analgesia requirement, postoperative pain and complications until postoperative day 14, and Patient and Observer Scar Assessment Score (POSAS) 6 months after surgery. RESULTS: Forty-one patients were randomized to each group. Visual analogue scale scores for wound-specific pain were lower in patients without a platysma suture 24 h after surgery (mean(s.d.) 3·15(1·46) versus 2·17(1·41) in groups with and without suture respectively; P = 0·002). There were no differences in the perioperative and postoperative need for analgesics, postoperative wound complications or cervical scar cosmesis 6 months after surgery (mean(s.d.) POSAS 23·99(9·53) versus 26·51(8·69); P = 0·148). CONCLUSION: Omitting the platysma muscle suture after thyroid surgery resulted in less wound-specific pain initially, with no difference in postoperative wound complications or cosmetic results. Registration number: NCT02951000 (http://www.clinicaltrials.gov).


Assuntos
Sistema Musculoaponeurótico Superficial/cirurgia , Tireoidectomia/métodos , Técnicas de Fechamento de Ferimentos , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Dor Pós-Operatória/epidemiologia , Método Simples-Cego , Técnicas de Sutura , Glândula Tireoide/cirurgia , Tireoidectomia/efeitos adversos , Adulto Jovem
4.
World J Surg Oncol ; 15(1): 190, 2017 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-29065879

RESUMO

BACKGROUND: The surgical resection extension in well-differentiated thyroid cancer is controversially discussed with the possibility of an overtreatment on the one hand against the risk of local disease recurrence. The aim of this study is to evaluate how the surgical resection extension with the adjunction of radioiodine therapy affects postoperative morbidity and the oncologic outcome of patients primarily treated for well-differentiated thyroid cancer. METHODS: All patients undergoing primary surgery for a well-differentiated, non-recurrent thyroid cancer from January 2005 to April 2013 at Tuebingen University Hospital were retrospectively analyzed. RESULTS: Papillary thyroid cancer (PTC) was present in 73 patients (including 27 papillary microcarinoma) and follicular thyroid cancer in 14 patients. Fifty-six of 87 patients (64%) underwent one-stage surgery, of which 26 patients (30%) received simultaneous lymph node dissection (LND). The remaining 31 patients (36%) underwent a two-stage completion surgery (29 patients with LND). Only in three patients a single lymph node metastasis was newly detected during two-stage completion surgery. Patients with LND at either one-stage and two-stage completion surgery had a significant higher rate of transient postoperative hypocalcemia. Postoperative adjuvant radioiodine therapy was performed in 68 of 87 patients (78%). After a median follow-up of 69 months [range 9-104], one local recurrence was documented in a patient suffering from PTC 23 months after surgery. CONCLUSION: No prophylactic two-stage lymphadenectomy should be performed in case of well-differentiated thyroid cancer to avoid unnecessary complication without any proven oncologic benefit.


Assuntos
Adenocarcinoma Folicular/terapia , Carcinoma Papilar/terapia , Esvaziamento Cervical/métodos , Recidiva Local de Neoplasia/epidemiologia , Neoplasias da Glândula Tireoide/terapia , Tireoidectomia/métodos , Adenocarcinoma Folicular/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Papilar/patologia , Estudos de Viabilidade , Feminino , Humanos , Radioisótopos do Iodo/uso terapêutico , Metástase Linfática , Masculino , Margens de Excisão , Pessoa de Meia-Idade , Esvaziamento Cervical/efeitos adversos , Recidiva Local de Neoplasia/patologia , Período Pós-Operatório , Prognóstico , Radioterapia Adjuvante/métodos , Estudos Retrospectivos , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia/efeitos adversos , Adulto Jovem
5.
Zentralbl Chir ; 142(1): 67-71, 2017 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-27657675

RESUMO

Background: Training in laparoscopic skills on simulators such as box-, POP- or VR-trainers improves intraoperative performance. Although this training is not mandatory in Germany at the moment, certified centres for minimally invasive surgery need to account for training opportunities. According to previous surveys, laparoscopic simulators are desired, yet not sufficiently available. The aim of the current project was a structured analysis of laparoscopic simulation sites in Germany. Materials and Methods: An online survey was performed among members of the "Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie". This consisted of 16 questions on the availability, type, use and financing of a laparoscopic simulator. If more than one person in an institution completed the questionnaire, answers were pooled and an analysis of clinics as well as single persons was performed. Results: Of 4605 persons, 422 participants (9.2 %) from 265 different departments completed the survey. In 140 Institutions (52.8 %) a simulator for laparoscopic training was present. No training possibility was available in 37.8 % (n = 99) of the hospitals. A curriculum for laparoscopic training was obtained in 43.3 % (n = 103) of the participants with laparoscopic training facilities. The use of available simulators by surgical residents increased when they were embedded in a mandatory training curriculum (at least monthly use: 33.3 vs. 57.1 %). Conclusion: Compared to previous surveys, the proportion of hospitals with simulators is increasing. Their use is currently very heterogenous. A mandatory basic curriculum may encourage acquisition of more simulators. A DGAV database is supposed to encourage cooperation between training centres and clinics without simulators.


Assuntos
Competência Clínica , Currículo , Internato e Residência , Laparoscopia/educação , Atitude do Pessoal de Saúde , Alemanha , Humanos , Assistentes Médicos/educação , Treinamento por Simulação , Sociedades Médicas , Inquéritos e Questionários , Interface Usuário-Computador
6.
Zentralbl Chir ; 141(3): 290-6, 2016 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-27331289

RESUMO

BACKGROUND: In-house surgical education and practical training of surgical skills are inhomogeneous in German hospitals and vary greatly in terms of teaching content and forms. The present survey provides an overview of the currently practiced surgical education and practical training of surgical skills in German hospitals. MATERIAL AND METHODS: An online survey was performed among members of the "Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie" (DGAV). It was a prospective data collection, divided into the following two groups: "junior physicians/consultants/senior physicians" and "chief physicians". The questionnaire consisted of 30 questions concerning the frequency, type and quality of in-house surgical education and practical training of surgical skills in German hospitals. RESULTS: A total of 325 physicians participated in the survey, including 61 chief physicians and 264 junior physicians/consultants/senior physicians. Amongst the participants, 107 (33 %) worked in university hospitals, 57 (18 %) in maximum care clinics, 73 (22 %) in major regional hospitals with specialised medical services and 88 (27 %) in basic care facilities. 199 (75.4 %) of the junior physicians/consultants/senior physicians reported a regular, 57 (21.6 %) an irregular and 8 (3.0 %) no formal surgical education or practical training of surgical skills in their hospitals. Assistance in substeps of an operation was considered to be very important by 72 % of the survey participants. Similarly, 71 % rated the practical teaching of basic surgical skills as very important. Furthermore, we investigated the availability of theoretical and practical training offerings as well as satisfaction with educational measures and their importance as assessed by the respondents. SUMMARY: The present survey illustrates the current state of surgical education and training in German hospitals. An implementation of pragmatic approaches such as the assistance in substeps of an operation and guided practical training of surgical skills might help to improve the satisfaction of physicians undergoing surgical training.


Assuntos
Competência Clínica , Currículo , Educação Médica Continuada , Educação de Pós-Graduação em Medicina , Cirurgia Geral/educação , Alemanha , Humanos , Corpo Clínico Hospitalar , Encaminhamento e Consulta , Especialidades Cirúrgicas/educação , Inquéritos e Questionários
7.
Tech Coloproctol ; 20(5): 273-278, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26940219

RESUMO

BACKGROUND: Natural orifice transluminal endoscopic surgery (NOTES) has seen considerable new developments in its evolution to a platform for rectal and sigmoid resection, but to date no true single NOTES procedure has been convincing. This study investigates the safety and feasibility of a further developed transanal NOTES platform for single-access NOTES rectosigmoid resection. METHODS: Ten large female pigs, mean weight 99.3 kg [standard deviation (SD) 7 kg, range 85.1-112.6 kg], underwent transanal rectosigmoid resection. Five animals were included in an acute study group with immediate postoperative euthanization. A second group included five animals in a survival study. Transanal rectosigmoid resections were performed with an elongated and curved transanal endoscopic operation (TEO) device. Coloanal anastomosis was performed using the transanal circular stapler technique. Survival follow-up was at 7 and 28 days via colonoscopy under sedation. RESULTS: Single-access NOTES transanal rectosigmoid resection with coloanal anastomosis was performed in nine out of ten female pigs. Mean length of rectosigmoid specimens exteriorized was 18.7 cm (SD 2.9 cm, range 14-23 cm). Mean operating time was 124 min (SD 35.7 min, range 70-166 min). Within the survival group, no complications occurred during the monitoring phase. In one case, there was ascites and colitis at necropsy as well as fibrosis at the anastomosis site. CONCLUSIONS: Pure transanal rectosigmoid resection is a feasible procedure. The approach via a single transanal access is demanding but viable with the elongated and curved TEO device. The newly developed scope offers an excellent view of the area cephalad to the promontory.


Assuntos
Colo Sigmoide/cirurgia , Colonoscopia/instrumentação , Endoscópios Gastrointestinais , Cirurgia Endoscópica por Orifício Natural/instrumentação , Reto/cirurgia , Animais , Colonoscopia/métodos , Colostomia/métodos , Estudos de Viabilidade , Feminino , Modelos Animais , Cirurgia Endoscópica por Orifício Natural/efeitos adversos , Cirurgia Endoscópica por Orifício Natural/métodos , Duração da Cirurgia , Suínos
8.
Zentralbl Chir ; 140(3): 255-8, 2015 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-26114633

RESUMO

Laparoscopic resection rectopexy is one of the surgical options for the treatment of external rectal prolapse. A standardised and reproducible procedure for this operation is a decisive advantage for such cases. The operation can be divided in 11 substeps, so-called nodal points, which must be reached before further progress can be made and simplify the operation by dividing the procedure into substeps. This manuscript and the accompanying film demonstrate the standardised laparoscopic resection rectopexy as taught in the "Surgical Training Center Tübingen," and performed at the University Hospital of Tübingen.


Assuntos
Colo Sigmoide/cirurgia , Laparoscopia/métodos , Prolapso Retal/cirurgia , Reto/cirurgia , Anastomose Cirúrgica/métodos , Humanos , Grampeamento Cirúrgico
9.
Tech Coloproctol ; 18(9): 813-6, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24667989

RESUMO

BACKGROUND: The aim of this study was to investigate the safety and efficacy of self-retaining barbed sutures in comparison with monofilament clip-fixated sutures for rectal wall closure in transanal endoscopic microsurgery. METHODS: Horizontal full-thickness wall defects (3.5 cm) of cattle rectal specimens were closed via transanal endoscopic microsurgery using a monofilament suture with clips at the end (Surgipro(®) 2/0; Covidien, Mansfield, MA, USA, n = 25) or a self-retaining barbed suture (V-Loc™ 180 3/0; Covidien, Mansfield, MA, USA, n = 25). The primary endpoint was the pneumatic leakage pressure of the suture line. As a secondary endpoint, suture time was evaluated. RESULTS: The median pneumatic leakage pressure for barbed sutures was 45.5 mbar (range 17-106 mbar) and 33.5 mbar (range 19-106 mbar) for monofilament sutures (p = 0.58). A pneumatic leak at a critical pressure below 25 mbar occurred in 3 cases with barbed sutures and in 7 cases with monofilament sutures (p = 0.29). Median suturing time [19:25 min:s (range 12:00-33:30) vs. 20:41 (17:00-28:33), p = 0.23] did not differ between the two groups. CONCLUSIONS: Barbed sutures display the same bursting pressure as monofilament sutures and their use for rectal wall closure seems feasible.


Assuntos
Microcirurgia/métodos , Reto/cirurgia , Suturas , Técnicas de Fechamento de Ferimentos , Canal Anal , Fístula Anastomótica , Animais , Bovinos , Endoscopia Gastrointestinal , Desenho de Equipamento , Microcirurgia/efeitos adversos , Pressão , Suturas/efeitos adversos , Fatores de Tempo , Técnicas de Fechamento de Ferimentos/efeitos adversos
10.
Eur J Pain ; 18(7): 902-13, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24449533

RESUMO

Appropriate pain therapy prior to diagnosis in patients with acute abdominal pain remains controversial. Several recent studies have demonstrated that pain therapy does not negatively influence either the diagnosis or subsequent treatment of these patients; however, current practice patterns continue to favour withholding pain medication prior to diagnosis and surgical treatment decision. A systematic review of PubMed, Web-of-Science and The-Cochrane-Library from 1929 to 2011 was carried out using the key words of 'acute', 'abdomen', 'pain', 'emergency' as well as different pain drugs in use, revealed 84 papers. The results of the literature review were incorporated into six sections to describe management of acute abdominal pain: (1) Physiology of Pain; (2) Common Aetiologies of Abdominal Pain; (3) Pre-diagnostic Analgesia; (4) Pain Therapy for Acute Abdominal Pain; (5) Analgesia for Acute Abdominal Pain in Special Patient Populations; and (6) Ethical and Medico-legal Considerations in Current Analgesia Practices. A comprehensive algorithm for analgesia for acute abdominal pain in the general adult population was developed. A review of the literature of common aetiologies and management of acute abdominal pain in the general adult population and special patient populations seen in the emergency room revealed that intravenous administration of paracetamol, dipyrone or piritramide are currently the analgesics of choice in this clinical setting. Combinations of non-opioids and opioids should be administered in patients with moderate, severe or extreme pain, adjusting the treatment on the basis of repeated pain assessment, which improves overall pain management.


Assuntos
Dor Abdominal/tratamento farmacológico , Analgésicos/uso terapêutico , Serviço Hospitalar de Emergência , Manejo da Dor , Doença Aguda , Humanos
11.
Zentralbl Chir ; 138(4): 397-9, 2013 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-23950075

RESUMO

The laparoscopic fundoplicatio is the "gold standard" among surgical therapy of gastrooesophageal reflux disease. In this context the Toupet fundoplicatio is an alternative indication to the Nissen fundoplicatio. The lesser dysphagia rate is specified as postoperative advantage. To avoid complications, a standardized procedure is relevant for a good postoperative outcome, even in more complex procedures. In this article, the indications and surgical methods are illustrated, as they are performed by the authors. The operation steps are demonstrated in addition to the text also in the attached video.


Assuntos
Fundoplicatura/métodos , Laparoscopia/métodos , Desenho de Equipamento , Fundoplicatura/instrumentação , Humanos , Laparoscopia/instrumentação , Instrumentos Cirúrgicos , Técnicas de Sutura/instrumentação
12.
Zentralbl Chir ; 138(2): 141-2, 2013 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-23564548

RESUMO

Currently laparoscopic cholecystectomy is the gold standard of therapy for diseases related with gallstones, namely symptomatic cholecystolithiasis, acute and chronic cholecystitis and also as therapy for gallbladder adenoids. Together with laparoscopic appendectomy, this procedure often is one of the first laparoscopic operations performed by new interns. Therefore a standardised, reproducible approach to ensure the patient safety is necessary. The procedure can be subdivided into 10 substeps--so-called "nodal points"--which must be completed before the next substep can be started. This article and the attached video show the ten "nodal points" of a standardised laparoscopic cholecystectomy.


Assuntos
Colecistectomia Laparoscópica/educação , Colecistectomia Laparoscópica/normas , Colecistolitíase/cirurgia , Internato e Residência , Cirurgia Vídeoassistida/educação , Benchmarking/normas , Colecistolitíase/diagnóstico , Alemanha , Humanos , Segurança do Paciente
13.
Chirurg ; 84(3): 202-7, 2013 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-23404250

RESUMO

High definition stereoscopic (3D) vision has been introduced into the operation theatre. This review exposes the optical and physiological background as well as the state of the art of 3D in laparoscopy. The distinguishing marks of 3D laparoscopes and monitors are listed and characteristics of stereoscopy, such as comfort zones and ghosting are explained. Suggestions for the practical use in the clinical routine should help to extract the best benefit possible from the new technology.


Assuntos
Percepção de Profundidade , Imageamento Tridimensional/instrumentação , Laparoscopia/instrumentação , Gravação em Vídeo/instrumentação , Artefatos , Desenho de Equipamento , Humanos , Aumento da Imagem/instrumentação
14.
Int J Colorectal Dis ; 27(7): 879-84, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22173715

RESUMO

PURPOSE: Radiotherapy is one of the important treatment modalities for tumors of pelvic organs. The fixed location of the rectum and its anatomic relationship with other pelvic organs makes it prone to radiation injury resulting in chronic radiation proctopathy in 5% to 20% of patients. Endothelial dysfunction has been associated with a number of pathophysiological processes. Endothelial cells synthesize and release various factors that regulate angiogenesis, inflammatory responses, hemostasis, as well as vascular tone and permeability. METHODS: Rectum tissue samples from 20 patients with established chronic radiation proctopathy were analysed for the expression of genes related to oxidative stress, tissue hypoxia, angiogenesis, and inflammation [endoglin (ENG), activin receptor-like kinase 1 (ALK1), platelet endothelial cell adhesion molecule 1 (PECAM), vascular endothelial growth factor (VEGF), fibroblast growth factor 2 (FGF2), hypoxia-inducible factor 1 (HIF-1), and interleukin-1 beta (IL-1ß)]. RESULTS: Overexpression of HIF-1, VEGF, FGF2, and IL-1ß was detected in affected tissue. For the first time, a significant suppression of activin receptor-like kinase 1 and ENG could be revealed. CONCLUSION: The data provided here allow further insight into the pathogenesis of radiation-induced rectum injury. Radiation-induced damage is not confined to a single event but involves complex signaling between different pathways, enhancing and maintaining the processes that lead to mucosal damage. The results indicate that postradiation tissue hypoxia is critical for fibrosis, which involves changes in the expression of profibrotic and angiogenic factors in rectal tissue.


Assuntos
Perfilação da Expressão Gênica , Radioterapia/efeitos adversos , Doenças Retais/etiologia , Doenças Retais/genética , Receptores de Activinas Tipo II/genética , Receptores de Activinas Tipo II/metabolismo , Idoso , Antígenos CD/genética , Antígenos CD/metabolismo , Endoglina , Feminino , Fator 2 de Crescimento de Fibroblastos/genética , Fator 2 de Crescimento de Fibroblastos/metabolismo , Regulação da Expressão Gênica , Humanos , Fator 1 Induzível por Hipóxia/genética , Fator 1 Induzível por Hipóxia/metabolismo , Interleucina-1beta/genética , Interleucina-1beta/metabolismo , Masculino , Pessoa de Meia-Idade , Molécula-1 de Adesão Celular Endotelial a Plaquetas/genética , Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo , RNA Mensageiro/genética , RNA Mensageiro/metabolismo , Receptores de Superfície Celular/genética , Receptores de Superfície Celular/metabolismo , Fator A de Crescimento do Endotélio Vascular/genética , Fator A de Crescimento do Endotélio Vascular/metabolismo
15.
Minerva Chir ; 66(6): 573-87, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22233664

RESUMO

Despite the introduction of proton pump inhibitors and modern flexible endoscopy techniques, upper gastrointestinal bleeding is still a common and serious condition. Once considered the domain of surgery, it is now uncommon to treat endoscopically controllable bleeding surgically. Therefore, most surgically treated cases are complicated and associated with a high mortality rate. This article presents the current management of upper gastrointestinal bleeding. Besides the description of current endoscopic treatment, medical prophylaxis and treatment, as well as radiological intervention, the article describes the indication and the surgical procedure.


Assuntos
Esofagoscopia , Hemorragia Gastrointestinal/terapia , Gastroscopia , Trato Gastrointestinal Superior , Algoritmos , Antibacterianos/uso terapêutico , Oclusão com Balão , Quimioterapia Combinada , Varizes Esofágicas e Gástricas/terapia , Medicina Baseada em Evidências , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/tratamento farmacológico , Hemorragia Gastrointestinal/etiologia , Hemorragia Gastrointestinal/cirurgia , Humanos , Incidência , Procedimentos Cirúrgicos Minimamente Invasivos , Úlcera Péptica Hemorrágica/terapia , Derivação Portossistêmica Transjugular Intra-Hepática , Guias de Prática Clínica como Assunto , Escleroterapia/métodos , Stents , Resultado do Tratamento , Vasoconstritores/uso terapêutico
16.
Obes Surg ; 19(8): 1143-9, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19513796

RESUMO

BACKGROUND: Morbid obesity is associated with gastroesophageal reflux (GERD). The aim of this prospective study was to determine esophageal motility in asymptomatic morbidly obese patients and compare it to non-obese individuals. METHODS: Forty-seven morbidly obese patients without GERD symptoms and 15 normal weight individuals were divided into four groups according to their body mass index (BMI; group I, <30 kg/m2; group II, 35-39.9 kg/m2; group III, 40-49.9 kg/m2; group IV, >or=50 kg/m2). Standard stationary water-perfused manometry was performed for the assessment of anatomy and function of the lower esophageal sphincter (LES). Twenty-four-hour ambulatory pH-metry and measurement of esophageal motility were performed with a microtransducer sleeve catheter. Data are given as mean+/-SD, and the results of groups II-IV were compared to the non-obese individuals from group I. RESULTS: Patients with morbid obesity had significantly lower LES pressures than non-obese individuals (I, 15.1+/-4.9; II-IV, 10.5+/-5.4, mmHg, p<0.05 vs. I) and showed an altered esophageal motility with respect to contraction frequency (I, 1.8+/-0.7/min; II-IV, 3.6+/-2.5/min; p<0.05 vs. I) and contraction amplitude (I, 38+/-12 mmHg; II-IV, 33+/-17 mmHg; p<0.05 vs. I). Furthermore, these patients had significantly higher DeMeester scores than non-obese individuals. Length and relaxation of the LES as well as propulsion velocity of the tubular esophagus did not differ. CONCLUSION: Patients with morbid obesity (=BMI>40 kg/m2) have a dysfunction of the LES and an altered esophageal motility, even when they are asymptomatic for GERD symptoms.


Assuntos
Transtornos da Motilidade Esofágica/fisiopatologia , Esfíncter Esofágico Inferior/fisiopatologia , Obesidade Mórbida/fisiopatologia , Adulto , Idoso , Índice de Massa Corporal , Transtornos da Motilidade Esofágica/diagnóstico , Feminino , Humanos , Masculino , Manometria , Pessoa de Meia-Idade , Contração Muscular , Obesidade Mórbida/diagnóstico , Pressão , Estudos Prospectivos , Índice de Gravidade de Doença , Adulto Jovem
17.
Eur J Surg Oncol ; 35(4): 368-72, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18378110

RESUMO

OBJECTIVE: The retrosigmoid intradural suprameatal approach includes the standard retrosigmoid suboccipital route with drilling of the petrous bone above and anterior of the internal auditory meatus, allowing for exposure of the trigeminal nerve within the Meckel's cave and of the middle fossa. In this study, the authors analyzed the potential use of an extended variation of the suprameatal route to approach the posterior cavernous sinus for microsurgery of, e.g., petroclival meningiomas and trigeminal schwannomas. METHODS: The microsurgical anatomy of the retrosigmoid suprameatal approach was examined by using 10 adult cadaveric specimens (20 sides), using 3-40x magnification. The exposure to the posterior cavernous sinus provided by this approach was focused. RESULTS: After drilling the suprameatal tubercle toward the petrous apex, the Meckel's cave was exposed. The trochlear nerve was the landmark for opening the cavernous sinus by this approach. The dura located medially to the entry point of the trochlear nerve into the tentorium was resected, allowing exposure of the intracavernous carotid artery with its meningohypophyseal trunk. CONCLUSION: The extended retrosigmoid intradural suprameatal approach allows exposure of the posterior cavernous sinus and may be used to remove lesions of the posterior fossa extending into the Meckel's cave and into the cavernous sinus.


Assuntos
Seio Cavernoso/anatomia & histologia , Seio Cavernoso/cirurgia , Neoplasias dos Nervos Cranianos/cirurgia , Meningioma/cirurgia , Microcirurgia/métodos , Neurilemoma/cirurgia , Doenças do Nervo Trigêmeo/cirurgia , Adulto , Cadáver , Seio Cavernoso/diagnóstico por imagem , Neoplasias dos Nervos Cranianos/patologia , Humanos , Processamento de Imagem Assistida por Computador , Meningioma/patologia , Neurilemoma/patologia , Osso Petroso/cirurgia , Base do Crânio/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Doenças do Nervo Trigêmeo/patologia
18.
Eur J Surg Oncol ; 35(5): 552-6, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-18653307

RESUMO

OBJECTIVE: The present anatomic study investigates alternative draining pathways of the petrosal vein territory, which allow compensation in case of surgical sacrifice. METHODS: In eight (four formaldehyde fixed and four alcohol fixed) specimens the petrosal vein complex has been dissected and studied. Three heads have been selectively injected via the superior petrous sinus with colored silicon in two different colors. Thereafter the posterior fossa content was removed epidurally from the skull and further fixed in 4% formaldehyde. The nervous and vascular structures were dissected under microscopic control, measured and photographed. 3D-photographs were elaborated. RESULTS: The petrosal vein was present in all cases and joined the superior petrous sinus always lateral to the trigeminal nerve as a single trunk. In the selectively injected specimens no passage of the colored silicon mixture to the contralateral venous brainstem territory could be discerned. However, the ipsilateral anastomoses to the deep supratentorial venous system--peduncular, anterolateral pontomesencephalic, lateral mesencephalic veins, and the tectal veins in connection with the pontotrigeminal vein--filled in all cases. CONCLUSION: Although the present anatomical model does not reflect physiological aspects of vascular dynamics, we document an apparently compensatory venous blood drainage occurring via anastomotic pathways directed to the ipsilateral supratentorial venous system. These findings represent an interesting aspect for preoperative image-guided planning in cerebello-pontine angle surgery.


Assuntos
Veias Cerebrais/anatomia & histologia , Neoplasias do Tronco Encefálico/cirurgia , Cadáver , Neoplasias Cerebelares/cirurgia , Humanos , Microcirurgia , Procedimentos Neurocirúrgicos , Osso Petroso , Tomografia Computadorizada por Raios X
19.
Endoscopy ; 40(7): 584-8, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18521795

RESUMO

BACKGROUND AND STUDY AIM: Perforation of the colon is a relatively rare complication of flexible endoscopy of the lower gastrointestinal tract. It has a reported incidence from between 0.2 % in diagnostic procedures to 0.5 % - 3 % in therapeutic procedures. Given the growing number of colonoscopies, the absolute number of iatrogenic perforations is not unimportant. The treatment of choice is most often surgical repair, since reliable and simple endoscopic techniques for perforation closure are currently unavailable. We aimed to evaluate our novel over-the-scope clip (OTSC) system for closure of iatrogenic perforations. MATERIAL AND METHODS: We have developed a nitinol clip that will capture perforations of 10 - 15 mm, compressing the lesions until healing. The OTSC was studied in a prospective experimental trial in pigs (50 - 60 kg, n=10) for the closure of an iatrogenic perforation of approximately 5 --10 mm on the serosal side, that was created by repeated endoscopic biopsy. The follow-up period was 12 weeks. Follow-up colonoscopy was performed at 4 and 12 weeks. Successful, tight closure of the lesion with absence of peritonitis in the postoperative course was the primary endpoint of the study. RESULTS: Nine animals had an uneventful clinical course. At termination of the study, macroscopic and microscopic examination of the clipping sites in the bowel wall showed normal tissue healing. One animal died 1 day postoperatively for reasons unrelated to the procedure. CONCLUSIONS: In this experimental study the OTSC clip system was found to be a simple and secure closure method for iatrogenic colon perforations, and thus might be an alternative to surgical repair.


Assuntos
Colo/cirurgia , Colonoscopia/efeitos adversos , Doença Iatrogênica , Perfuração Intestinal/cirurgia , Instrumentos Cirúrgicos , Ligas , Animais , Colo/lesões , Feminino , Masculino , Suínos
20.
Endoscopy ; 39(12): 1100-2, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18072063

RESUMO

Gastric perforation is a rare complication after acute necrotizing pancreatitis. We describe endoscopic closure of a gastric perforation that appeared 4 days after surgical necrosectomy including splenectomy due to necrotizing pancreatitis, using the over-the-scope clip (OTSC) system (Ovesco Endoscopy GmbH, Tübingen, Germany). The clips, which are made of nitinol, are loaded onto an application cap which is mounted on the distal tip of the endoscope. The lesion was closed with two clips and the patient recovered well without reinterventions. The lesions showed normal healing on follow-up.


Assuntos
Gastroscopia/métodos , Pancreatite Necrosante Aguda/complicações , Ruptura Gástrica/cirurgia , Adulto , Endoscopia/métodos , Seguimentos , Gastroscópios , Humanos , Masculino , Pancreatectomia/efeitos adversos , Pancreatectomia/métodos , Pancreatite Necrosante Aguda/diagnóstico , Pancreatite Necrosante Aguda/cirurgia , Complicações Pós-Operatórias/cirurgia , Medição de Risco , Esplenectomia/efeitos adversos , Esplenectomia/métodos , Ruptura Gástrica/etiologia , Instrumentos Cirúrgicos , Resultado do Tratamento
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