Wettability and adhesion of nanotubes applied to the surface of titanium implants by anodic oxidation.

The aim of this study was to evaluate the wettability and adhesion of self-organized TiO2 nanotubes formed on the surface of 8 commercially pure titanium (CP-Ti) disks and 12 dental implants (n = 12) by anodization in a glycerol-H2O (50-50 v/v) electrolyte containing NH4F. Two disk specimens were not submitted to anodization (controls). The nanotubes thus obtained had average dimensions of 50 nm in diameter by 900 nm in length. The treated disk specimens were stored for 2, 14 and 35 days (n = 2), and the wettability of their surfaces was evaluated with a goniometer at the end of each storing period. The adhesion of nanotubes to titanium was evaluated by field emission scanning electron microscopy after subjecting the 12 implants to a simulation of clinical stress in two-part synthetic bone blocks. After installing the implants with the application of an insertion torque, the two halves of the block were separated, and the implants were removed. The nanotubes remained adhered to the substrate, with no apparent deformation. The contact angles after 14 days and 35 days were 16.47° and 17.97°, respectively, values significantly higher than that observed at 2 days, which was 9.24° (p < 0.05). It was concluded that the method of anodic oxidation tested promoted the formation of a surface suitable for clinical use, containing nanotubes with levels of wettability and adhesion to titanium compatible with those obtained by other methods found in the literature. The wettability, however, did not prove stable over the tested storage periods.

Relationship between Roughness and Wettability of Nine Types of Implant Surfaces and Potential Interference of Surface Oxygen and Carbon: In Vitro Evaluation.

Aim: To assess the roughness and hydrophilicity of nine types of dental implant surfaces, while also examining the presence of contaminants carbon and oxygen on these surfaces. Furthermore, the study investigated potential correlations between these characteristics across the analyzed surfaces. Materials and Methods: The surfaces analyzed were as follows: MI: machined (turned), Implacil implant; TOI: blasted with titanium oxide, Implacil implant; TOAEI: blasted with titanium oxide and acid-etched, Implacil implant; ZAED: blasted with zirconia and acid-etched, DSP implant; CPD: coated with calcium phosphate, DSP implant; XD: subjected to an experimental treatment (patent pending), DSP implant; DAEHAS: double acid-etched and activated with hydroxyapatite nano-crystals, SIN implant; DAES: double acid-etched, SIN implant; and AMP: untreated surface of the Plenum implant, produced by additive manufacturing. Four and five disc-shaped specimens were used in the hydrophilicity and roughness assessments, respectively. Roughness was evaluated by optical profilometry and scanning electron microscopy; hydrophilicity was determined using the sessile-drop technique; and the chemical analysis was performed using X-ray photoelectron spectroscopy. The Kruskal- Wallis, Mann-Whitney, and Spearman correlation tests were employed to analyze the data (p < 0.10). Results: Significant differences were observed among the analyzed surfaces in terms of both roughness and hydrophilicity (p < 0.001). The surface exhibiting the highest roughness was AMP, whereas the greatest hydrophilicity was exhibited by CPD. Correlations between roughness and hydrophobicity were observed for MI (r = 0.936, p = 0.009), ZAED (r = 0.957, p = 0.004), and DAES (r = 0.964, p = 0.005). The carbon concentration observed on the CPD surface was lower than that observed on the other surfaces, whereas the oxygen concentrations were similar. No correlations were observed between the presence of contaminants and the roughness or hydrophilicity characteristics. Conclusion: Roughness and hydrophilicity values exhibited considerable variation among the tested surfaces. Aside from the CPD surface, comparable concentrations of carbon and oxygen were detected. Although correlations between roughness and hydrophilicity were observed only for the ZAED, DAES, and MI surfaces, these correlations were inadequate to establish a causal relationship between the two surface characteristics.

Does Pre-Emptive Administration of Intravenous Ibuprofen (Caldolor) or Intravenous Acetaminophen (Ofirmev) Reduce Postoperative Pain and Subsequent Narcotic Consumption After Third Molar Surgery?

PURPOSE: Pre-emptive analgesia is known to reduce postoperative pain after third molar removal. The purpose of this study was to compare postoperative pain in patients receiving either preoperative intravenous (IV) ibuprofen or preoperative IV acetaminophen for third molar surgery. PATIENTS AND METHODS: This study was a randomized, single-blinded clinical study conducted in patients undergoing surgical extraction of 2 or more impacted third molars under deep sedation. This study compared 2 interventions: 800 mg of IV ibuprofen (Caldolor; Cumberland Pharmaceuticals, Nashville, TN) and 1,000 mg of IV acetaminophen (Ofirmev; Mallinckrodt Pharmaceuticals, Staines-upon-Thames, United Kingdom). The primary outcome variable was postoperative pain measured on a visual analog scale at different time points. The secondary outcome variable was the amount of postoperative analgesic (narcotic and over-the-counter) medication taken in both groups. The Mann-Whitney U test was used to compare groups in terms of outcomes, the χ2 test was used to assess associations between nominal variables, and Spearman correlations were used to assess associations between continuous variables. Significance was set at P < .05. RESULTS: The study sample consisted of 58 patients (39 female and 19 male patients). A total of 41 patients (IV ibuprofen, n = 19; IV acetaminophen, n = 22) completed the study. Equal distributions of age, gender, and number of impacted teeth were noted between the groups. At 4 hours postoperatively, the pain level in the ibuprofen group was significantly lower than that in the acetaminophen group (P = .004). This trend continued at 24 hours (P = .019) and 48 hours (P = .017). The average amount of narcotic medication taken in the ibuprofen group (2.68 ± 2.26 doses) was lower than that in the acetaminophen group (7.32 ± 6.68 doses), and the result was statistically significant (P = .005). CONCLUSIONS: Pre-emptive analgesia with IV ibuprofen is more effective than IV acetaminophen in reducing postoperative pain and opioid use for third molar surgery.

Bone Volume Changes After Sinus Floor Augmentation with Heterogenous Graft.

PURPOSE: The aim of this study was to evaluate the volumetric stability of deproteinized bovine bone after sinus augmentation, using cone beam computed tomography (CBCT) and three-dimensional (3D) analysis. MATERIALS AND METHODS: Using a specific selection tool and 3D reconstruction from InVesalius 3.0, volumetric analysis of CBCT scans was performed in patients undergoing a sinus elevation technique in critical defects, using deproteinized bovine bone. The first scan was performed immediately after graft surgery (T1), and the second was performed 8 months after graft surgery (T2). RESULTS: A total of 13 patients met the inclusion criteria of this retrospective study; 26 postoperative CBCT scans were analyzed for these patients. All patients exhibited an increase in bone volume (9.10%). The mean bone volume increase from T1 to T2 was 0.137 cm(3) (SD: ± 0.104 cm(3)). There was a statistically significant correlation between bone volume and time (P < .0001). The mean bone volume was 1.506 cm(3) (SD: ± 0.473 cm(3)) for T1 and 1.644 cm(3) (SD: ± 0.506 cm(3)) for T2. CONCLUSION: Within the limited sample, the study demonstrated an increase in graft volume after sinus elevation with deproteinized bovine bone in critical defects.

Tratamento alternativo de extensa perfuração da membrana sinusal: 36 meses de acompanhamento clínico / Alternative treatment for large perforation of the maxillary sinus membrane: 36 months of follow-up

Na reabilitação implantossuportada em pacientes com edentulismo maxilar com atrofia óssea, em decorrência da reabsorção e pneumatização do seio maxilar, frequentemente, tem sido utilizada a técnica de elevação do assoalho do seio maxilar, que pode resultar em complicações, incluindo a perfuração da membrana de Schneider. Assim, o objetivo deste estudo foi relatar a técnica alternativa para o tratamento de uma extensa perfuração da membrana sinusal durante uma cirurgia de elevação do assoalho do seio maxilar. Paciente do sexo feminino, com 55 anos de idade. Durante a cirurgia de elevação da membrana sinusal, ocorreu perfuração de aproximadamente 2 cm de extensão. O tratamento proposto foi a técnica alternativa com utilização de membrana de colágeno, para reparar a membrana de Schneider e possibilitar a inserção e manutenção do substituto ósseo. No caso exposto, a membrana de colágeno reabsorvível demonstrou ser um método eficaz para o tratamento de uma extensa perfuração da membrana sinusal.

Generally, the sinus lifting technique has been used for patients with extensive atrophic areas in the maxillary arch due to the pneumatization process, but complications can be found, including the Schneider membrane perforation. Thus, the aim of this article is to present a clinical alternative to treat a large perforation of the sinus membrane during the surgical process. A 55 years-old female patient demonstrated a 2 cm width tearing during the operation. The proposed treatment was the use of a collagen membrane to repair the surgical field and to provide access for the bone substitute. The combined procedure is an efficient method in this kind of maxillary sinus complication.