1.
Bioorg Med Chem Lett
; 82: 129149, 2023 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36690039
RESUMO
A series of 1-O-acyl- and 1-oxo-kamebanin analogues were prepared from kamebanin, isolated from Rabdosia excisa and their cytotoxicity was assayed on HL60 promyelocytic leukemia cells and HCT116 human colon cancer cells. The structure-activity relationship study showed that the presence of 1-O-acyl groups of a C3-C5 carbon chain increased the cytotoxic activity.