Synergistic SERS enhancement of NiCo-LDHs microurchins and silver nanoparticles for ultra-sensitive and reusable detection of thiabendazole.

Two-dimensional layered semiconductor materials as a distinctive class of materials are comprehensively explored for widespread applications due to narrow bandgap, controllable morphology, and tunable metal cation composition. Herein, we constructed a sensing platform of surface enhanced Raman spectroscopy (SERS) by combination of nickel­cobalt layered double hydroxide (NiCo-LDH) microurchins and plasmonic silver nanoparticles (Ag NPs) for fungicide detection of thiabendazole (TBZ). The NiCo-LDHs/Ag-NPs microcomposites consist of NiCo-LDHs microurchins having a large number of nanoneedles deposited with photoreduced Ag NPs. The SERS platform with NiCo-LDHs/Ag-NPs shows an excellent SERS performance for TBZ detection, including an ultra-low detection limit of 1.49 × 10-11 M, a sublime enhancement factor of 1.71 × 109, high uniformity, good reproducibility, and long-term storage stability. The ultrahigh SERS activity of NiCo-LDH/Ag-NPs can be attributed to strong electromagnetic enhancement in the nanoscale gaps between Ag NPs, massive charge transfer through large-area NiCo-LDH/Ag-NPs interfaces, and the synergistic action of electromagnetic and charge transfer mechanisms. Besides, the unique morphology of NiCo-LDHs/Ag-NPs microcomposite provides a broad surface area for adsorption of TBZ molecules for further Raman signal enhancement. The practicability of the proposed SERS platform is confirmed by detecting TBZ in the real samples of apple juice and river water. The exceptional self-cleaning capability of the NiCo-LDHs/Ag-NPs microcomposite with an retention rate of 81.97 % even after the fifth degradation cycle underscores its impressive sustainable reusability and cost-effectiveness. The findings in this work lay the foundation for the development of high-performance SERS platforms to ensure food safety and environmental protection.

3D/2D-Bismuth Oxybromide Spheres with Selenium-Doped Graphitic Carbon Nitride Sheets: An Efficient Electrocatalyst for the Detection of Arsenic Drug Roxarsone.

Heavy metals are crucial carcinogenic agents threatening the environment and living habituates. Among them, arsenic (As) is an important metalloid that is categorized as a group I toxic carcinogen. Roxarsone (RX) is an organoarsenic antibiotic compound primarily used as a veterinarian drug and growth promoter for poultry animals. The extensive usage of RX increased the accumulation of As in living beings and the ecosystem. Therefore, we have prepared an electrochemical sensor based on 3D bismuth oxybromide with 2D selenium-doped graphitic carbon nitride (BOB/SCN) electrocatalyst for the rapid detection of RX. The elemental and structural details were thoroughly investigated with several spectroscopic techniques. The electrochemical properties were measured by impedance and voltammetric measurements. The electrocatalytic behavior toward the RX was estimated with different voltammetric methods. Therefore, our BOB/SCN-based electrochemical sensor demonstrated a low detection limit (2.3 nM), low quantification value (7.7 nM), optimal sensitivity (0.675 µA µM-1 cm-2), and good linear ranges (0.01-77 and 77-857 µM). Additionally, this sensor showed good electrochemical performance and was applied to monitor the RX in various real samples with remarkable recoveries. Based on these results, our BOB/SCN sensor is a promising electrochemical platform for determining RX.

Silver nanopopcorns decorated on flexible membrane for SERS detection of nitrofurazone.

The synthesis of three-dimensional silver nanopopcorns (Ag NPCs) onto a flexible polycarbonate membrane (PCM) for the detection of nitrofurazone (NFZ) on the fish surface by surface-enhanced Raman spectroscopy (SERS) is presented. The proposed flexible Ag-NPCs/PCM SERS substrate exhibits significant Raman signal intensity enhancement with the measured enhancement factor of 2.36 × 106. This is primarily attributed to the hotspots created on Ag NPCs, including numerous nanoscale protrusions and internal crevices distributed across the surface of Ag NPCs. The detection of NFZ by this flexible SERS substrate demonstrates a low limit of detection (LOD) of 3.7 × 10-9 M and uniform and reproducible Raman signal intensities with a relative standard deviation below 8.34%. It also exhibits excellent stability, retaining 70% of its efficacy even after 10 days of storage. Notably, the practical detection of NFZ in tap water, honey water, and fish surfaces achieves LOD values of 1.35 × 10-8 M, 5.76 × 10-7 M, and 3.61 × 10-8 M, respectively,  which highlights its effectiveness across different sample types. The developed Ag-NPCs/PCM SERS substrate presents promising potential for sensitive SERS detection of toxic substances in real-world samples.

Hydrothermal synthesis of iron titanate hexagonal nanoplates for electrochemical detection of nitrofurazone.

An electrochemical sensor is established using an iron titanate (FeTiO3) modified glassy carbon electrode (GCE) to detect nitrofurazone. Various microscopic and spectroscopic analysis was performed to reveal the properties of the prepared FeTiO3 hexagonal nanoplates. The FeTiO3/GCE presents enhanced electrochemical response to nitrofurazone at the peak reduction potential of - 0.471 V with a larger peak current than the bare GCE due to high electrical conductivity, enhanced specific surface area, and abundant active sites. The superior nitrofurazone detection performance includes the low limit of detection of 0.002 µM and the sensitivity of 0.551 µA µM-1 cm-2 in the linear concentration range of 0.01-162.2 µM. The reproducibility and selectivity studies of the FeTiO3/GCE show excellent results with a relative standard deviation of < 5%. The practicability of FeTiO3/GCE is confirmed by monitoring nitrofurazone in actual samples. This work demonstrates that perovskite-type FeTiO3 has great potential in real-world sample analysis, and provides a new way to develop high-performance electrochemical sensors.

In-situ growth of MOF-derived Co3S4@MoS2 heterostructured electrocatalyst for the detection of furazolidone.

The over-exploitation of antibiotics in food and farming industries ruined the environmental and human health. Consequently, electrochemical sensors offer significant advantages in monitoring these compounds with high accuracy. Herein, MOF-derived hollow Co3S4@MoS2 (CS@MS) heterostructure has been prepared hydrothermally and applied to fabricate an electrochemical sensor to monitor nitrofuran class antibiotic drug. Various spectroscopic methodologies have been employed to elucidate the structural and morphological information. Our prepared electrocatalyst has better electrocatalytic performance than bare and other modified glassy carbon electrodes (GCE). Our CS@MS/GCE sensor exhibited a highly sensitive detection by offering a low limit of detection, good sensitivity, repeatability, reproducibility, and stability results. In addition, our sensor has shown a good selectivity towards the target analyte among other potential interferons. The practical reliability of the sensor was measured by analyzing various real-time environmental and biological samples and obtaining good recovery values. From the results, our fabricated CS@MS could be an active electrocatalyst material for an efficient electrochemical sensing application.

Synergism of Holmium Orthovanadate/Phosphorus-Doped Carbon Nitride Nanocomposite: Nonenzymatic Electrochemical Detection of Hydrogen Peroxide.

Developing efficient and robust electrode materials for electrochemical sensors is critical for real-time analysis. In this paper, a hierarchical holmium vanadate/phosphorus-doped graphitic carbon nitride (HoVO4/P-CN) nanocomposite is synthesized and used as an electrode material for electrochemical detection of hydrogen peroxide (H2O2). The HoVO4/P-CN nanocomposite exhibits superior electrocatalytic activity at a peak potential of -0.412 V toward H2O2 reduction in alkaline electrolytes while compared with other reported electrocatalysts. The HoVO4/P-CN electrochemical platform operated under the optimized conditions shows excellent analytical performance for H2O2 detection with a linear concentration range of 0.009-77.4 µM, a high sensitivity of 0.72 µA µM-1 cm-2, and a low detection limit of 3.0 nΜ. Furthermore, the HoVO4/P-CN-modified electrode exhibits high selectivity, remarkable stability, good repeatability, and satisfactory reproducibility in detecting H2O2. Its superior performance can be attributed to a large specific surface area, high conductivity, more active surface sites, unique structure, and synergistic action of HoVO4 and P-CN to benefit enhanced electrochemical activity. The proposed HoVO4/P-CN electrochemical platform is effectively applied to ascertain the quantity of H2O2 in food and biological samples. This work outlines a promising and effectual strategy for the sensitive electrochemical detection of H2O2 in real-world samples.

Efficient photocatalytic degradation of textile dye pollutants using thermally exfoliated graphitic carbon nitride (TE-g-C3N4).

Graphitic carbon nitride (g-C3N4), an organic photocatalyst was reported to have beneficial properties to be used in wastewater treatment applications. However, g-C3N4, in its bulk form was found to have poor photocatalytic degradation efficiency due to its inherent limitations such as poor specific surface area and fast electron-hole pair recombination rate. In this study, we have tuned the physiochemical properties of bulk g-C3N4 by direct thermal exfoliation (TE-g-C3N4) and examined their photocatalytic degradation efficiency against abundant textile dyes such as methylene blue (MB), methyl orange (MO), and rhodamine B (RhB). The degradation efficiencies for MB, MO, and RhB dyes are 92 ± 0.18%, 93 ± 0.31%, and 95 ± 0.4% respectively in 60 min of UV light irradiation. The degradation efficiency increased with an increase in the exfoliation temperature. The prepared catalysts were characterized using FTIR, XRD, FE-SEM, EDAX, BET, and UV-DRS. In BET analysis, TE-g-C3N4 samples showed improved surface area (48.20 m2/g) when compared to the bulk g-C3N4 (5.03 m2/g). Further, the TE-g-C3N4 had 2.98 times higher adsorption efficiency than the bulk ones. The free radicals scavenging studies revealed that the superoxide radicals played an important role in the photodegradation for dyes, when compared to the hydroxyl radical (.OH) and the photo-induced holes (h+), Photoluminescence (PL) emission and electrochemical impedance spectroscopy (EIS) spectra of TE-g-C3N4 indicated a lowered electron-hole pairs' recombination rate and an increased photo-induced charge transfer respectively. Further, the TE-g-C3N4 were found to have excellent stability for up to 5 cycles with only a minor decrease in the activity from 92% to 86.2%. These findings proved that TE-g-C3N4 was an excellent photocatalyst for the removal and degradation of textile dyes from wastewater.

Molecularly Imprinted Polymer-Based Biomimetic Systems for Sensing Environmental Contaminants, Biomarkers, and Bioimaging Applications.

Molecularly imprinted polymers (MIPs), a biomimetic artificial receptor system inspired by the human body's antibody-antigen reactions, have gained significant attraction in the area of sensor development applications, especially in the areas of medical, pharmaceutical, food quality control, and the environment. MIPs are found to enhance the sensitivity and specificity of typical optical and electrochemical sensors severalfold with their precise binding to the analytes of choice. In this review, different polymerization chemistries, strategies used in the synthesis of MIPs, and various factors influencing the imprinting parameters to achieve high-performing MIPs are explained in depth. This review also highlights the recent developments in the field, such as MIP-based nanocomposites through nanoscale imprinting, MIP-based thin layers through surface imprinting, and other latest advancements in the sensor field. Furthermore, the role of MIPs in enhancing the sensitivity and specificity of sensors, especially optical and electrochemical sensors, is elaborated. In the later part of the review, applications of MIP-based optical and electrochemical sensors for the detection of biomarkers, enzymes, bacteria, viruses, and various emerging micropollutants like pharmaceutical drugs, pesticides, and heavy metal ions are discussed in detail. Finally, MIP's role in bioimaging applications is elucidated with a critical assessment of the future research directions for MIP-based biomimetic systems.

Recent Advances in Two-Dimensional MXene-Based Electrochemical Biosensors for Sweat Analysis.

Sweat, a biofluid secreted naturally from the eccrine glands of the human body, is rich in several electrolytes, metabolites, biomolecules, and even xenobiotics that enter the body through other means. Recent studies indicate a high correlation between the analytes' concentrations in the sweat and the blood, opening up sweat as a medium for disease diagnosis and other general health monitoring applications. However, low concentration of analytes in sweat is a significant limitation, requiring high-performing sensors for this application. Electrochemical sensors, due to their high sensitivity, low cost, and miniaturization, play a crucial role in realizing the potential of sweat as a key sensing medium. MXenes, recently developed anisotropic two-dimensional atomic-layered nanomaterials composed of early transition metal carbides or nitrides, are currently being explored as a material of choice for electrochemical sensors. Their large surface area, tunable electrical properties, excellent mechanical strength, good dispersibility, and biocompatibility make them attractive for bio-electrochemical sensing platforms. This review presents the recent progress made in MXene-based bio-electrochemical sensors such as wearable, implantable, and microfluidic sensors and their applications in disease diagnosis and developing point-of-care sensing platforms. Finally, the paper discusses the challenges and limitations of MXenes as a material of choice in bio-electrochemical sensors and future perspectives on this exciting material for sweat-sensing applications.

Hierarchical 3D Snowflake-like Iron Diselenide: A Robust Electrocatalyst for Furaltadone Detection.

An electrocatalyst with a large active site is critical for the development of a high-performance electrochemical sensor. This work demonstrates the fabrication of an iron diselenide (FeSe2)-modified screen-printed carbon electrode (SPCE) for the electrochemical determination of furaltadone (FLD). It has been prepared by the facile method and systematically characterized with various microscopic/spectroscopic approaches. Due to advantageous physiochemical properties, the FeSe2/SPCE showed a low charge-transfer resistance value of 200 Ω in 5.0 mM [Fe(CN)6]3-/4- containing 0.1 M KCl. More importantly, the FeSe2/SPCE exhibited superior catalytic performance compared to the bare SPCE for FLD sensing based on the electrochemical response in terms of a peak potential of -0.44 V (vs Ag/AgCl (sat. KCl)) and cathodic response current of -22.8 µA. Operating at optimal conditions, the FeSe2-modified electrode showed wide linearity from 0.01 to 252.2 µM with a limit of detection of 0.002 µM and sensitivity of 1.15 µA µM-1 cm-2. The analytical performance of the FeSe2-based platform is significantly higher than many previously reported FLD electrochemical sensors. Furthermore, the FeSe2/SPCE also has a promising platform for FLD detection with high sensitivity, good selectivity, excellent stability, and robust reproducibility. Thus, the finding above shows that the FeSe2/SPCE is a highly suitable candidate for the electrochemical determination of glucose levels for real-time applications such as in human urine and river water samples.

Synthesis of perovskite-type potassium niobate using deep eutectic solvents: A promising electrode material for detection of bisphenol A.

This study demonstrates a hydrothermal method to prepare perovskite-type potassium niobate (KNbO3) through deep eutectic solvent (DES), which is further used as an electrode material for the determination of bisphenol A (BPA). The as-synthesized KNbO3 was systematically characterized by different microscopic and spectroscopic techniques. The KNbO3-modified electrode demonstrates excellent electrocatalytic activity for BPA compared to the pristine electrode. The enhanced performance of the proposed sensor is attributed to the numerous active sites, large electrochemical surface area, high electrical conductivity, and rapid electron transfer. The fabricated sensor shows a wide detection range (0.01-84.3 µM), a low limit of detection (0.003 µM), a high sensitivity (0.51 µA µM-1 cm-2), and good anti-interference abilities towards the BPA detection by linear sweep voltammetry method. Besides, it was successfully applied to determining BPA in food samples, demonstrating good practicability. This design paves a new way to fabricate efficient electrode material for various electrochemical applications using a DES medium.

Structural growth of zinc oxide nanograins on carbon cloth as flexible electrochemical platform for hydroxychloroquine detection.

Pharmaceutical pollution that imposes a health threat worldwide is making accurate and rapid detection crucial to prevent adverse effects. Herein, binder-free zinc oxide nanograins on carbon cloth (ZnO NGs@CC) have been synthesized hydrothermally and employed to fabricate a flexible electrochemical sensor for the quantification of hydroxychloroquine (HCQ) that is typical pharmaceutical pollution. The characteristics of ZnO NGs@CC were investigated by various in-depth electron microscopic, spectroscopic and electroanalytical approaches. Compared with the pristine CC platform, the ZnO NGs@CC platform exhibits superior electrochemical performance in detecting HCQ with a large oxidation current at a low over-potential of +0.92 V with respect to the Ag/AgCl (Sat. KCl) reference electrode. With the support of desirable characteristics, the fabricated ZnO NGs@CC-based electrochemical sensor for HCQ detection displays good performances in terms of wide sensing range (0.5-116 µM), low detection limit (0.09 µM), high sensitivity (0.279 µA µM-1 cm-2), and strong selectivity. By the resulting 3D hierarchical nanoarchitecture, ZnO NGs@CC has progressive structural advantages that led to its excellent electrochemical performance in sensing applications. Furthermore, the electrochemical sensor is employed to detect HCQ in biological and environmental samples and also achieves good recovery rates. Thus, the designed ZnO NGs@CC demonstrates admirable electrochemical activity toward HCQ real-time monitoring and would be an excellent electrochemical platform for HCQ sensing.

Zinc Oxide/Phosphorus-Doped Carbon Nitride Composite as Potential Scaffold for Electrochemical Detection of Nitrofurantoin.

Herein, we present an electrocatalyst constructed by zinc oxide hexagonal prisms/phosphorus-doped carbon nitride wrinkles (ZnO HPs/P-CN) prepared via a facile sonochemical method towards the detection of nitrofurantoin (NF). The ZnO HPs/P-CN-sensing platform showed amplified response and low-peak potential compared with other electrodes. The exceptional electrochemical performance could be credited to ideal architecture, rapid electron/charge transfer, good conductivity, and abundant active sites in the ZnO HPs/P-CN composite. Resulting from these merits, the ZnO HPs/P-CN-modified electrode delivered rapid response (2 s), a low detection limit (2 nM), good linear range (0.01-111 µM), high sensitivity (4.62 µA µM-1 cm2), better selectivity, decent stability (±97.6%), and reproducibility towards electrochemical detection of NF. We further demonstrated the feasibility of the proposed ZnO HPs/P-CN sensor for detecting NF in samples of water and human urine. All the above features make our proposed ZnO HPs/P-CN sensor a most promising probe for detecting NF in natural samples.

Three-dimensional manganese cobaltate: a highly conductive electrocatalyst for paraoxon-ethyl detection.

The synthesis of manganese cobaltate (MnCo2O4) with the hybrid three-dimensional architecture has been developed as an electrocatalyst for the electrochemical sensing of paraoxon-ethyl (PEL). The detailed physicochemical and structural characterization of MnCo2O4 is meticulously examined. The MnCo2O4-modified screen-printed carbon electrode (SPCE) exhibits good electrocatalytic activity for the reduction of PEL compared with the bare SPCE due to numerous unique properties. By profiting from these advantages, the proposed MnCo2O4/SPCE shows superior sensing performance toward the determination of PEL, including low cathodic peak potential (- 0.64 V), wide detection range (0.015-435 µM), low limit of detection (0.002 µM), high detection sensitivity (2.30 µA µM-1 cm-2), excellent selectivity, and good reproducibility. Notably, the electrochemical performance of the MnCo2O4-based electrocatalyst is superior to those previously reported in the literatures. The practical application of the MnCo2O4/SPCE is effectively assessed in the analysis of food and water samples with satisfied recoveries of 96.00-99.35%. The superior performance of the proposed MnCo2O4 electrocatalyst holds considerable potential for future development of electrochemical sensing platforms.

Construction of a Copper Bismuthate/Graphene Nanocomposite for Electrochemical Detection of Catechol.

Binary metal oxides with carbon nanocomposites have received extensive attention as research hotspots in the electrochemistry field owing to their tunable properties and superior stability. This work illustrates the development of a facile sonochemical strategy for the synthesis of a copper bismuthate/graphene (GR) nanocomposite-modified screen-printed carbon electrode (CBO/GR/SPCE) for the electrochemical detection of catechol (CT). The formation of an as-prepared CBO/GR nanocomposite was comprehensively characterized. The electrochemical behavior of the CBO/GR/SPCE toward CT was investigated by voltammetry and amperometry techniques. The fabricated CBO/GR/SPCE manifests an excellent electrocatalytic performance toward CT with a lower peak potential and a higher current value compared to those of CBO/SPCE, GR/SPCE, and bare SPCE. It is attributed to enhanced electro-catalytic activity, synergetic effects, and good active sites of the CBO/GR nanocomposite. Under the electrochemical condition, the CBO/GR/SPCE displayed a wide linear sensing range, trace-level detection limit, acceptable sensitivity, and excellent selectivity. Furthermore, our proposed CBO/GR electrode was employed successfully for CT detection in water samples.

Synergistic formation of samarium oxide/graphene nanocomposite: A functional electrocatalyst for carbendazim detection.

Herein, an electrochemical sensor based on samarium oxide anchored, reduced graphene oxide (Sm2O3/RGO) nanocomposite was developed for the rapid detection of carbendazim (CBZ). Different characterization methods were infused to deeply examine the morphology, composition, and elemental state of Sm2O3/RGO nanocomposite. The Sm2O3/RGO modified electrode exhibits an excellent electro-catalytic performance toward CBZ detection with a peak potential of +1.04 V in phosphate buffer solution (pH 3.0), which is superior to the RGO-, Sm2O3- and bare- electrodes. This remarkable activity can be credited to the synergetic effect generated by the robust interaction between Sm2O3 and RGO, resulting in a well-enhanced electrochemical sensing ability. Impressively, the fabricated sensor shows improved electrochemical performance in terms of the wide working range, detection limit, and strong sensitivity. On a peculiar note, the electrochemical sensing performances of CBZ detection based on Sm2O3/RGO nanocomposite demonstrate an extraordinary behavior compared to the prior documented electro-catalyst. In addition, the fabricated Sm2O3/RGO sensor also displays good operational stability, reproducibility, and repeatability towards the detection of CBZ. Furthermore, it was successfully applied to the CBZ detection in food and environmental water samples with satisfactory recovery. In accordance with our research findings, the Sm2O3/RGO nanocomposite could be used as an electro-active material for effectual electrochemical sensing of food and environmental pollutants.

Tailored construction of one-dimensional TiO2/Au nanofibers: Validation of an analytical assay for detection of diphenylamine in food samples.

We report a one-dimensional titanium dioxide encapsulated with gold heterojunction nanofibers (TiO2/Au NFs) as robust electrocatalysts for electrochemical detection of diphenylamine (DPA). A TiO2/Au NFs were successfully synthesized by a coaxial electrospinning method. The formation of TiO2/Au NFs was confirmed by various analytical and spectroscopic approaches. The fabricated TiO2/Au NFs modified screen-printed carbon electrodes (SPCE) exhibit a well-enhanced detection activity towards DPA sensing as compared to other electrodes. Under the experimental conditions, the proposed electrode leading to the sensing range from 0.05 to 60 µM with a detection limit of 0.009 µM was obtained for the DPA detection. Moreover, the TiO2/Au NFs/SPCE showed good selectivity towards the electrochemical oxidation of DPA. Interestingly, the TiO2/Au NFs modified electrode was then applied to detect the effect of DPA on spiked content in the food samples.

Electrochemical Behavior of Three-Dimensional Cobalt Manganate with Flowerlike Structures for Effective Roxarsone Sensing.

Rational design and construction of the finest electrocatalytic materials are important for improving the performance of electrochemical sensors. Spinel bioxides based on cobalt manganate (CoMn2O4) are of particular importance for electrochemical sensors due to their excellent catalytic performance. In this study, three-dimensional CoMn2O4 with the petal-free, flowerlike structure is synthesized by facile hydrothermal and calcination methods for the electrochemical sensing of roxarsone (RXS). The effect of calcination temperature on the characteristics of CoMn2O4 was thoroughly studied by in-depth electron microscopic, spectroscopic, and analytical methods. Compared to previous reports, CoMn2O4-modified screen-printed carbon electrodes display superior performance for the RXS detection, including a wide linear range (0.01-0.84 µM; 0.84-1130 µM), a low limit of detection (0.002 µM), and a high sensitivity (33.13 µA µM-1 cm-2). The remarkable electrocatalytic performance can be attributed to its excellent physical properties, such as good conductivity, hybrid architectures, high specific surface area, and rapid electron transportation. More significantly, the proposed electrochemical sensor presents excellent selectivity, good stability, and high reproducibility. Besides, the detection of RXS in river water samples using the CoMn2O4-based electrochemical sensor shows satisfactory recovery values in the range of 98.00-99.80%. This work opens a new strategy to design an electrocatalyst with the hybrid architecture for high-performance electrochemical sensing.

Zinc Manganate: Synthesis, Characterization, and Electrochemical Application toward Flufenamic Acid Detection.

The construction of novel electrocatalysts for efficient and economic electrochemical sensors is continuously a significant conceptual barrier for the point-of-care technology. Binary metal oxides with heterostructures have gained plenty of attention due to their promising physicochemical properties. Herein, we develop a rapid and sensitive electrochemical probe for the detection of flufenamic acid (FFA) by using a zinc manganate (ZnMnO)-modified electrode. The formation of ZnMnO was confirmed by various analytical techniques, such as X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy, and field-emission scanning electron microscopy with energy dispersive X-ray spectroscopy and elemental mapping. The ZnMnO-based electrocatalyst, which was used for the electrochemical detection of FFA, shows better performance than the previously reported electrode materials. The ZnMnO assay shows a linear quantitative range from 0.05 to 116 µM with a limit of detection of 0.003 µM and sensitivity of 0.385 µA µM-1 cm-2. Its good electrochemical performance can be ascribed to the large surface area, rapid charge mass transfer, copious active sites, and high carrier mobility. The electrochemical study displays that the fabricated ZnMnO-based sensor has the potential to be applied in the clinical analysis. This work constructs an advanced functional electrode material with a microscale architecture for the point-of-care technology.

Hierarchical nanoarchitecture of zirconium phosphate/graphene oxide: Robust electrochemical platform for detection of fenitrothion.

We report the rational design of nanocomposite with zirconium phosphate encapsulated on graphene oxide (ZrP/GO) for the highly sensitive and selective analysis of fenitrothion (FT). The characteristics of ZrP/GO nanocomposite are systematically analyzed by various in-depth electron microscopic, spectroscopic and analytical techniques. The ZrP/GO nanocomposite modified electrodes show better electrochemical response towards FT than other electrodes. The improved electrochemical activity of nanocomposite is attributed to large surface area, high conductivity, numerous active surface sites, GO nanosheets served as the conductivity matrix while preventing ZrP from agglomeration and the synergistic effect of ZrP and GO. Benefitting from the unique features, our fabricated sensor exhibits the superior performance in terms of wide working range (0.008-26 µM), appropriate peak potential (-0.61 V), low limit of detection (0.001 µM), high sensitivity (6 µA µM-1 cm-2) with the regression coefficient of 0.999. Additionally, the electrochemical sensor also displays good selectivity, excellent stability (99.6%), reproducibility (4.9%) and reusability (6.1%). The practical applicability of ZrP/GO sensor is shown by performing the detection of FT in water samples. These results clearly suggest that the ZrP/GO nanocomposite is an efficient electrode material for the future real-time environmental monitoring of FT.