[Toxoplasma gondii antibodies in pregnant women in the Ceské Budejovice District]. / Protilátky proti Toxoplasma gondii u gravidních zen v okrese Ceské Budejovice.

In 1984-1986 in the district of Ceské Budejovice in the southern part of the Czech Republic pregnant women were subjected to serological examinations for antibodies against Toxoplasma gondii. A total of 3,392 women were examined within the age bracket 16-54 years. For the serological examination parallel examinations were made using Sabin-Feldman test (SFT) and the complement fixation test (CFT). In SFT the basic serum dilution was 1:4, in CFT 1:10. Pregnant women were examined once or repeatedly. During the first examination which was usually made between the second and third month of pregnancy the total (SFT and CFT) prevalence was 37%. In the SFT antibodies were detected in 35%, in CFT in 25%. The second blood sample was taken during the 4th-5th month of pregnancy and subsequent samples during the 8th-9th month of pregnancy. In women who were examined twice or repeatedly (a total of 1,409 women), the dynamics of prevalence of antibodies were recorded. 64% women were permanently negative, 33% women were permanently positive with the same or a slightly varying titre and in 3% women during pregnancy, seroconversion was observed or a significant rise of antibodies. In 20 women where seroconversion or a significant rise of antibodies was found data were collected to find out whether in their children from birth to the age of 12-13 years toxoplasmosis was diagnosed. The toxoplasmosis was not diagnosed in these children.

[Acute ischemia of the extremities in the puerperal period]. / Akutní ischémie koncetin v poporodním období.

The development of pharmacotherapy implies great advantages for patients, at the same time it is, however, also the source of more frequent side-effects of drugs, which may result also from mutual interactions of commonly used drugs. The authors describe a case of ergotism which developed as a result of drug interaction between the ergot uterotonic Cornutamine and the marcolid antibiotic Erythromycin. This interaction could have seriously damaged the health of the young woman. At the same time the authors remind of the clinical picture of ergotism and the possible way of its treatment. In the Czechoslovak literature no report on this interaction was published during the past three years.

[Actinomycoses of the female genitalia in connection with IUD insertion]. / Antinomykóza zenských rodidel v souvislosti se zavedením IUD.

PIP: Abdominal actinomycoses with genital localization are relatively rare, but their occurrence has been increasing recently due to more extensive use of IUDs. After a brief review of the etiology, diagnosis, and treatment of this disease, 3 cases of IUD-induced genital actinomycosis are described. All 3 women were in their 40s. In 2 cases, the disease developed within a week after the IUD had been extracted. The patients were hospitalized with a diagnosis of adnexitis, which was confirmed by histological tests, anaerobic cultures, and microscopic examination. In all 3 cases, surgery was followed by antibiotic therapy with megadoses of crystalline PNC, Entisol, and subsequent long-term treatment with ampicillin. The treatment was successful; the women recovered to an almost normal gynecological condition.^ieng