RESUMO
A study was made of magnesium content in the blood serum and the urine of 62 patients with thyrotoxicosis before and after the parenteral administration of magnesium sulfate (load dose). Blood serum magnesium content was diminished; as to its renal excretion--it failed to differ from that in the control group. The mentioned disturbances in magnesium content were more pronounced in patients with thyrotoxicosis for a long time.
Assuntos
Hipertireoidismo/metabolismo , Rim/metabolismo , Magnésio/metabolismo , Adolescente , Adulto , Ritmo Circadiano , Eletrocardiografia , Feminino , Bócio Nodular/metabolismo , Doença de Graves/metabolismo , Humanos , Sulfato de Magnésio , Masculino , Pessoa de Meia-IdadeRESUMO
A decreased content of the organospecific antigen (thyroglobulin) was found in the tissues of 70% of thyroid gland cancers and in about 50% of thyroid benign tumours and thyrotoxic goiters studied. These data testify to the fact that the antigenic simplification is not an obligatory and specific process for the malignant transformation of thyroid tissue. Among the neoplasms with decreased thyroglobulin content there were found tumours built up both of "A" and "C" cellular types, thus indicating the dual nature of the antigenic simplification of the thyroid tumours.