[Combined effect of laser radiation and alternating magnetic fields on Staphylococci]. / Kombinirovannoe vliianie lazernykh izluchenii i peremennykh magnitnykh polei na stafilokokki.

The influence of infrared and helio-neon lasers, alternate magnetic fields and their combination on the growth phases of staphylococci was studied. The study revealed that in most cases the inhibition of the growth phases of staphylococci was caused by the treatment of staphylococcal cultures with alternate magnetic fields in combination with infrared laser irradiation. The most effective treatment conditions were found.

[Action of benzohydrothiochromylium salts on bacterial membranes]. / Deistvie solei benzogidrotiokhromiliia na membrannyi apparat bakterii.

Cultivation of Staphylococcus 209-P and Micrococcus lysodeikticus cells on media containing new antibacterial preparations--iodide and trifluoroacetate derivatives of benzohydrothiochromylium resulted in a remarkable lesion of the membrane respiratory apparatus, i.e. the amounts of membrane polypeptides, the specific concentration of cytochromes, the activities of reductases and oxidases--NADH, malate and lactate decreased. Profound changes in the cell cytology were observed.

[The effect of nitrofurans on the membrane apparatus of coccal bacteria]. / Deistvie nitrofuranov na membrannyi apparat bakterii kokkovoi gruppy.

Secondary membrane effects on the membrane apparatus of coccus bacteria were being studied. Cultivation of Micrococcus lysodeikticus and Staphylococcus aureus cells on subbacteriostatic concentrations of nitrofurans results in a lower biosynthesis of many membrane proteins, as well as in inhibiting the activity of respiratory enzymes, i. e. the specific concentration of cytochromes and specific activity of NADH-, malate-, lactate oxidases and some reductases drop. Some cytological changes were revealed, when cells were grown on solafur, furazolidone, and furacriline.

[Comparative study of the action of different antibiotics on the membrane dehydrogenase activity in Micrococcus lysodeikticus]. / Sravnitel'noe izuchenie deistviia razlichnykh antibiotikov na aktivnost' degidrogenaz membran u Micrococcus lysodeikticus.

The object of this work was to study the effect of antibiotics belonging to the groups of penicillin, tetracycline and aminoglycosides on the activity of lactate dehydrogenase, alcohol dehydrogenase and malate dehydrogenase in the membranes of Micrococcus lysodeikticus. Streptomycin, benzylpenicillin, carbenicillin and phenoxymethylpenicillin decreased the activity of the above dehydrogenases. Tetracycline and oxytetracycline activated lactate dehydrogenase and alcohol dehydrogenase in the membranes, but decreased their activity in the supernatant fraction of disintegrated membranes. The enzyme activity in the membranes was particularly inhibited by neomycin.

[The combined effect of supraoptimal temperature and chemotherapeutic preparations on the metabolism of adenylic nucleotides by Staphylococcus aureus]. / Kombinirovannoe vliianie supraoptimal'noi temperatury i khimioterapevticheskikh preparatov na obmen adenilovykh nukleotidov u Staphylococcus aureus

Comparative investigation of the effect of nitrofurans on the metabolism of adenylic nucleotides of Staphylococcus aureus at 36 degrees and 40 degrees C was made. It was shown that increasing of the cultivation temperature intensified the bacteristatic effect of nitrofurans. The use of nitrofurans at supraoptimal temperature intensified the activity of ATP-ase and considerably decreased the ATP, ADP and increased the AMP of Staphylococcus aureus.