Rhinocerebral Mucormycosis in a COVID-19 Patient from Nepal: A Case Report.

With the surge of cases during the second wave of COVID-19 in Nepal, a number of mucormycosis coinfection cases have also come to our attention. We present a case of a 65-year-old female who was admitted to our emergency department with complaints of pain, swelling, and tingling sensation of the left side of the face along with blood-tinged nasal discharge for 20 days. She had been tested positive for COVID-19 a month back and managed with oxygen support and corticosteroids. Magnetic Resonance Imaging showed invasive fungal sinusitis, with the positive black turbinate sign and mild extension along with the dura mater of the left temporal lobe, and left cavernous sinus. She was diagnosed with rhinocerebral mucormycosis and managed with systemic antifungal therapy and insulin. As per the treatment modality, surgical debridement could not be done because the patient did not give consent.

Techno-economic feasibility of algal aquaculture via fish and biodiesel production pathways: A commercial-scale application.

The industrialization of integrated algae-aquaculture systems entails appropriate information regarding environmental and economic assessments, field and laboratory analyses, and feasibility studies. Accordingly, Scenedesmus obliquus was cultivated in a raceway pond (300 m3), and the algal biomass was used as a protein source for the growth of Nile tilapia (Oreochromis niloticus). Nile tilapia fish was cultivated in five commercial-scale tanks for 44 weeks, having a productivity of 15-20 kg (live weight)·m-3. Among various algal-based fish meals, the diet containing 7.5% microalgae provided the largest body length (29 cm) and weight (402 g), as well as the optimum growth performance parameters. Scenedesmus obliquus was subjected to lipid extraction, and the defatted biomass was also used as a substitute for fishmeal in diets. Nile tilapia grown using the lipid-extracted algae had improved health status, and the biochemical composition was satisfactory. Further, two scenarios were economically investigated: Case 1, the direct use of algal biomass for fish production, and Case 2, the utilization of algae for biodiesel production followed by the application of residual biomass in fishmeal diets. Based on field experiments and financial information reported in the literature, the two options would offset their initial investment cost within payback periods of 7.5 and 6.8 yr, respectively.

Draft Genome Sequence of Hexachlorohexane (HCH)-Degrading Sphingobium lucknowense Strain F2T, Isolated from an HCH Dumpsite.

Sphingobium lucknowense F2(T), isolated from the hexachlorocylcohexane (HCH) dumpsite located in Ummari village, Lucknow, India, rapidly degrades HCH isomers. Here we report the draft genome of strain F2 (4.4 Mbp), consisting of 4,910 protein coding genes with an average G+C content of 64.3%.