Can serum tumor necrosis factor-alpha predict peritoneal adhesions prior to secondary laparoscopic procedures?

AIM OF THE STUDY: This study aimed to investigate the incidence and degree of postoperative intra-abdominal adhesions(POAs) in secondary laparoscopic procedures and assess the power of the preoperative levels of tumor necrosis factor-alpha(TNF-α) and interleukin-1 beta(IL-1ß) and selected peripheral inflammatory biomarkers(PIBs) in the prediction of the development and extent of POA. PATIENTS AND METHODS: This prospective study enrolled 103 patients who had previously undergone at least one or more laparoscopic abdominal or gynecological operations. We examined TNF-α, IL-1ß, and PIBs, namely C-reactive protein, white blood cell count, neutrophil-to-lymphocyte ratio(NLR), platelet-to-lymphocyte ratio, and systemic immune-inflammation index(SII) according to the presence, location, and score of adhesions determined during secondary laparoscopic procedures. RESULTS: Only age, postoperative adhesion index(PAI) score, NLR, SII, TNF-α, and IL-1ß resulted in a significant difference in the existence of adhesion(P<0.05). The correlation analysis of TNF-α with variables showed that the PAI score and IL 1ß levels had a significantly positive correlation. CONCLUSION: The presence and extent of POA could be predicted by examining the preoperative TNF-α level in patients who had laparoscopic abdominal surgery previously. We could overcome adverse events during secondary laparoscopic procedures by assessing high-risk patients and integrating a personalized surgical approach to managing selected patients.

Effects of attachment type and palatal coverage on oral perception and patient satisfaction in maxillary implant-supported complete denture patients.

AIM: The effect of oral rehabilitation on the oral perception of implant-supported overdenture patients is a concern. This study evaluated the effects of the attachment type and palatal coverage on oral perception and patient satisfaction in maxillary implant-supported complete denture patients. SUBJECTS AND METHODS: The correlation between oral perceptual ability (OPA) and patient satisfaction in three groups was investigated. Group I consisted of dentate individuals (n = 40), Group II consisted of maxillary implant-supported complete denture patients with bar attachments and palatal coverage (n = 12), and Group III of maxillary implant-supported complete denture patients with magnetic attachments and palatal coverage (n = 14). In addition, implant-supported maxillary overdentures with bar attachments, with (Group II; n = 12) and without (Group IV; n = 18) palatal coverage, were examined in terms of patient satisfaction and OPA. The relationship between OPA and patient satisfaction was assessed with the Turkish version of the Oral Health Impact Profile-14 (OHIP-TR-14) satisfaction survey. To compare oral sensory function among the groups, tactile awareness and pressure awareness were assessed. RESULTS: There was no significant difference in OHIP-TR-14 scores between Groups II and III. In addition, there was no correlation between oral tactile function and patient satisfaction in Groups II and III. For patients with maxillary bar-retained implant-supported overdentures, palatal coverage did not affect the correlation between OPA and patient satisfaction, lateral pressure threshold, or tactile thickness threshold. CONCLUSION: According to the results of the study, whether maxillary implant-supported overdentures were made with a bar- or magnetic-type retainer, and whether bar-retained implant-supported overdentures had an open or closed palate did not affect the correlation between patient satisfaction and oral perception.

Evaluation and comparison of the film thicknesses of six temporary cements before and after thermal cycling.

AIM: Temporary cement can be applied for both permanent and temporary cementation of implant-supported fixed restorations. These cements must have certain physical and mechanical properties. Specifically, the film thickness directly affects the cement's clinical success. The aim of this study was to evaluate and compare the film thicknesses of six temporary cements before and after thermal cycling. MATERIALS AND METHODS: Eighty-four metal copings with uniform holding loops were fabricated and divided into 12 groups of seven samples each. Six of these groups were subjected to a thermal cycling process. The copings were cemented to solid implant abutments (Implance Solid Abutment, 3.5-mm cervical diameter, 2 mm high, 6° taper, Implance Dental Implant System; AGS Medical, Trabzon, Turkey), using six different types of cement. The fitting surfaces were coated with the luting cements. After steeping in artificial saliva for 24 hours, the specimens were subjected to pull-out testing using an Instron machine. Specimens in the thermal cycling groups were subjected to 700 thermal cycles (36-55°C) prior to pull-out testing. RESULTS: The Mann-Whitney U test revealed significant differences between the retention values of the thermal cycling (+) and thermal cycling (-) groups (U = 153.0, P < 0.01). The retention values of the groups subjected to thermal cycling were significantly lower than those of the cements that were not subjected to thermal cycling. Thermal cycling also affected the film thickness significantly (Wilcoxon signed rank test, Z = -5.533, P < 0.001). CONCLUSIONS: Thermal cycling affects the film thickness and retention of temporary cements significantly. The retention value was significantly higher for glass ionomer cement than for the other cements tested, and this cement also exhibited greatest film thickness.

The In Vitro comparison of the retention of an implant-supported stud attachment locator and straumann ball attachment at different angulations.

AIM: In this study, we investigated the retention of two attachment types, Straumann ball (SB) and Straumann Locator® (SL) attachments, on different implant angulations and identified the most appropriate treatment type or attachment system for each angulation. MATERIALS AND METHODS: The attachments placed on angulation of 0°-, 10°-, and 20° implants were subjected to 1440 vertical insertion-separation cycles. The retention values of the attachments after 0, 720, and 1440 cycles were measured using the Instron machine. In addition, scanning electron microscopy images of the attachments and abutments were obtained before and after the insertion-separation process. RESULTS: There was a significant difference between the SB and SL attachments that were placed on 0° after 1440 cycles (P < 0.05) and between 20° SB and 20° SL attachments after 720 and 1440 cycles (P < 0.05) in terms of retention. No significant difference was observed between 20° SB and 20° SL attachments at 0 cycles (P > 0.05). CONCLUSIONS: In implants with a 20° angle, retention of stud attachments decreased more than ball attachments after use. Thus, the total angle between the implants should not be <20° if long-term retention is desired when using stud attachments. For implants with angles >20°, 6-month patient controls are required to control retention of attachments by considering factors in the mouth with the two tested attachment systems.

Use of platelet-rich plasma in periodontal surgery--a prospective randomised double blind clinical trial.

The aim of this prospective controlled randomized clinical trial was to evaluate the additional effect of platelet-rich plasma (PRP) in attachment gain. Twenty-two patients showing contralateral intrabony defects were included. Defects were randomized to beta-TCP (Cerasorb) in combination with PRP (test) or alone (control). Probing pocket depth (PPD), clinical attachment level (CAL), and relative AL (RAL) were assessed at the first, initial, re-evaluation (or basis examinations) and 6 months after surgery. Defect dimensions were recorded at baseline surgery (day 0) and during re-entry surgery (after 6 months), with vertical depth of the defect as primary outcome variable. An early healing index (EHI) was assessed 3 days, 1, 2 and 4 weeks after surgery. Both treatments led to clinical improvements. The median reduction of open vertical depth was 1.9 mm (interquartile intervals, 0.75 and 2.5 mm) at test sites, compared with 2.6 mm (1.8 and 3.5 mm) at control sites (p = 0.19, Wilcoxon). The median reductions of PPD and CAL at the four sites in close proximity to the defect in the interproximal area at test sites were 0.8 and 0.28 mm, and at control sites 0.4 and 0.13 mm, respectively. The EHI showed a reduction from grade 3 after 3 days to grade 1 after 4 weeks. PRP did not improve the results achieved with beta-TCP in the treatment of intrabony defects.

Evaluation of periodontal parameters in patients undergoing peritoneal dialysis or hemodialysis.

OBJECTIVE: To analyze and compare periodontal parameters in chronic renal failure (CRF) patients undergoing peritoneal dialysis (PD) therapy with a group of patients on hemodialysis (HD) treatment and healthy controls (C). PARTICIPANTS: Seventy-five PD patients (mean age: 44 +/- 12 years) were matched with 41 HD patients (mean age: 46 +/- 15 years) and 61 C (mean age: 46 +/- 18 years). METHODS: Plaque (PI) and calculus (CSI) accumulation and gingival bleeding (GI) were recorded with the appropriate indices. Periodontal condition was assessed using the probing pocket depth (PPD). One-way anova test, Pearson chi-squared test, Mann-Whitney U-test and Kruskal-Wallis test were performed to compare PD patients with HD patients and healthy C. RESULTS: Plaque Index values were significantly higher (P < 0.001) in the PD and HD groups than the C group. GI values were significantly higher (P < 0.01) in the HD group than the PD group. Finally, CSI values in the PD and HD groups were also significantly higher (P < 0.001) than the C group. CONCLUSIONS: Chronic renal failure patients on PD treatment are more susceptible to periodontal diseases like HD patients. Thus, it is very important to maintain an optimal oral hygiene level. Further studies on periodontal parameters of only PD patients are needed to get more information on the oral health status of this patient group.

Hypoplasminogenaemia, gingival swelling and ulceration.

This article reviews the evolution of the history related to an unusual type of generalized gingival swelling we first described in a single adult British patient; then recognized by us and others in small cohorts in Turkey; later found in several countries worldwide. We finally recognized it to represent the oral manifestations of plasminogen deficiency (hypoplasminogenaemia).

Dental and periodontal findings in hemodialysis patients.

OBJECTIVE: Oral health problems of chronic renal failure patients can compromise systemic health. This study compared the periodontal and dental health status of patients on hemodialysis (HD) with healthy controls (C). STUDY DESIGN: Seventy-six HD patients and 61 controls were examined for plaque deposits, gingivitis, periodontitis, calculus accumulation and oral health status. RESULTS: There was no statistically significant difference in the measurement of probing pocket depths (PPD) in HD and C groups, but a highly significant difference was found for plaque index (P < 0.001), gingival index (GI) (P = 0.007) and calculus surface index (P < 0.001). There was a highly significant difference for GI (P = 0.001) and PPD scores (P < 0.001) between subgroups receiving HD for <3 years or more. A positive correlation between time on dialysis and parameter of missing teeth (r = 0.259; P = 0.024), GI scores (r = 0.474; P < 0.001) and measurement of PPD (r = 0.481; P < 0.001) was found in the HD group. Decayed, missing and filled teeth index scores were higher in the controls than the HD group, with no statistical significance. CONCLUSIONS: The dental and periodontal health status of HD patients is comparable with healthy controls, but becomes worse with time on dialysis. Thus, oral health maintenance is of utmost importance in this patient group.