Routine laboratory parameters in estimating mortality and morbidity in COVID-19 diagnosed cases followed in the intensive care unit.

OBJECTIVE: In this study, our goal was to assess the neutrophil/lymphocyte, platelet/lymphocyte ratios, urea/albumin, lactate, C-reactive protein/albumin procalcitonin/albumin, dehydrogenase/albumin, and protein/albumin rates in 368 critical COVID-19 cases following the entrance to the intensive care unit (ICU) to investigate the effects of biomarkers on prognosis and mortality. PATIENTS AND METHODS: The Ethics Committee approved this study carried out in our hospital's intensive care units between March 2020 and April 2022. 368 patients, 220 (59.8%) male, and 148 (40.2%) female, diagnosed with COVID-19 and aged between 18 and 99 years were included in this research. RESULTS: The average age of non-survivors was statistically considerably higher than survivors (p<0.05). There was no numerical significance in terms of gender concerning mortality (p>0.05). The duration of ICU stay was statistically considerably prolonged in survivors than in those who did not survive (p<0.05). The leukocytes, neutrophils, urea, creatinine, ferritin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), creatine kinase (CK), C-reactive protein (CRP), procalcitonin (PCT), and pro-brain natriuretic peptide (pro-BNP) levels were numerically considerably higher in the non-survivors (p<0.05). The platelet, lymphocyte, protein, and albumin levels statistically considerably declined in non-survivors in comparison with survivors (p<0.05). CONCLUSIONS: Acute renal failure (ARF) increased mortality by 31.815-fold, ferritin by 0.998-fold, pro-BNP by 1-fold, procalcitonin by 574.353-fold, neutrophil/lymphocyte by 1.119-fold, CRP/albumin by 2.141-fold, and protein/albumin by 0.003-fold. It was found that the number of days in the ICU increased mortality by 1.098-fold, creatinine by 0.325-fold, CK by 1.007-fold, urea/albumin by 1.079-fold, and LDH/albumin by 1.008-fold.

Reliability of low-flow anesthesia procedures in patients undergoing laparoscopic cholecystectomy: Their effects on our costs and ecological balance.

Background and Aim: The many advantages of low-flow anesthesia are now recognized. Apart from its positive effects on the patient, it is clear that it is a method that all anesthetists should prefer with its positive effects on the ecological balance. Patients and Methods: This prospective, observational, cross-sectional study included 80 patients aged 18-65 years with an American Society of Anesthesiologists score of 1-2 (ASA I-II) who were scheduled for laparoscopic cholecystectomy. Results: Although the operation time and anesthesia duration were higher in the low anesthesia group group, sevoflurane consumption was lower. Considering the operation times, up to 60% savings were achieved. Conclusion: In our study, we safely applied low-flow anesthesia to our patients with advanced monitoring. We believe that low-flow anesthesia is advantageous in terms of both patients' health, ecological balance, and cost.