RESUMO
Nonsteroidal anti-inflammatory drugs are widely used and relatively safe medications. We report here an uncommon case of fluid retention simulating acute congestive heart failure, secondary to aspirin consumption, promptly reversible after discontinuation of therapy, and triggered again by pharmacological challenge test.
Assuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Aspirina/efeitos adversos , Insuficiência Cardíaca/induzido quimicamente , Desequilíbrio Hidroeletrolítico/induzido quimicamente , Adulto , Feminino , HumanosRESUMO
Research has identified circadian and seasonal patterns for several acute cardiovascular diseases. In order to investigate the possible existence of a seasonal variation in the onset of acute nontraumatic ruptures of thoracic aorta, this study considered all patients referred to the emergency department of St Anna Hospital of Ferrara, Italy, from January 1985 to December 1996. In the considered period, 85 patients (52 males, 33 females) of nontraumatic ruptures of thoracic aorta were observed. Cosinor analysis and partial Fourier series with up to 4 harmonics were applied to monthly data, and the best-fitting curves for circannual rhythmicity were calculated. A higher winter occurrence with a significant peak in January was found for the total population and the male subgroup. Although the underlying factors are not fully known, such patterns strictly resemble that of arterial blood pressure. Emergency doctors can put to practical use the recognition of a clearly identified chronorisk for aortic rupture, increasing alertness, and providing the most effective antihypertensive protection at the specific vulnerable periods.
Assuntos
Aneurisma da Aorta Torácica/epidemiologia , Aneurisma da Aorta Torácica/etiologia , Ruptura Aórtica/epidemiologia , Ruptura Aórtica/etiologia , Estações do Ano , Distribuição por Idade , Idoso , Serviço Hospitalar de Emergência/tendências , Feminino , Análise de Fourier , Hospitais de Ensino/tendências , Humanos , Hipertensão/complicações , Itália/epidemiologia , Masculino , Encaminhamento e Consulta/tendências , Fatores de Risco , Ruptura Espontânea , Distribuição por Sexo , Fatores de TempoRESUMO
The aim of the study was to verify whether there is a seasonal pattern in the occurrence of cranial nerve paralysis. All patients admitted to the Emergency Department of St Anna Hospital, Ferrara, Italy, from 1 January 1991 to 31 December 1997, were reviewed. Cranial nerve paralysis was diagnosed in 126 cases: the oculomotor nerve accounted for 46 cases, the trochlear nerve for 14, and the abducens nerve for 66. The frequencies of cases involving the oculomotor nerve and of all cases were significantly higher in winter than in the other seasons. Compared with other 2-month periods, the highest number of total cases occurred in November to December. Chronobiological analysis of the data for individual months showed a rhythmic 12-month pattern for the total population, with a weakly significant peak in January.
