Assuntos
Perfilação da Expressão Gênica/métodos , Células Germinativas/metabolismo , Células-Tronco Pluripotentes/metabolismo , Animais , Diferenciação Celular/genética , Linhagem Celular , Proteínas Cromossômicas não Histona , Proteínas de Ligação a DNA/genética , Embrião de Mamíferos/citologia , Proteínas de Homeodomínio/genética , Humanos , Camundongos , Proteína Homeobox Nanog , Fator 3 de Transcrição de Octâmero/genética , Proteínas/genética , Proteínas de Ligação a RNA/genética , Proteínas Repressoras/genética , Células-Tronco/citologia , Fatores de TempoRESUMO
A computerized system for precise stimulation and analysis of electroencephalographic (EEG) reactions to two simultaneously presented frequencies of sine-wave light (one constant, 13 Hz, and the other varying from 1 to 6 Hz and vice versa) was used to study the mechanisms of human brain reactivity to complex rhythmical stimulation. The frequencies were generated by computer and presented to the subjects by three different ways: as a result of their simple summation (additively), as a product of their multiplication (multiplicatively, amplitude modulation of constant frequency by the varying frequency), or by separate presentation to different eyes. The dynamics of electroencephalograms for different types of stimulation were compared. Under all three experimental conditions, the dynamics of EEG spectra has demonstrated the same general pattern of resonance activation, which was similar to that observed for the presented signals in the case of their amplitude modulation. Significant positive shifts in the functional state of subjects were observed as a result of stimulation. The results obtained show the leading role of the processes of amplitude modulation in the interaction of integrative, adaptive, and trace mechanisms of the brain functioning during human perception of complex rhythmical stimuli.