1.
Ann Hematol
; 100(12): 3049-3050, 2021 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32978674
Assuntos
Antineoplásicos Alquilantes/uso terapêutico , Neoplasias do Sistema Nervoso Central/tratamento farmacológico , Linfoma de Células T/tratamento farmacológico , Temozolomida/uso terapêutico , Idoso , Encéfalo/efeitos dos fármacos , Encéfalo/patologia , Neoplasias do Sistema Nervoso Central/patologia , Neoplasias do Sistema Nervoso Central/secundário , Feminino , Humanos , Linfoma de Células T/patologia
2.
J Med Cases
; 11(10): 303-305, 2020 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34434334
RESUMO
Disseminated intravascular coagulation (DIC) is characterized by systemic activation of coagulation pathway which can lead to thrombosis and bleeding. Chronic DIC associated with aortic aneurysm or dissection commonly presents with bleeding symptoms with variable severity due to enhanced fibrinolysis. Patients with unexplained bleeding diathesis with DIC should include aortic disease as one of the differential diagnoses. This paper reports two patients with severe hemorrhagic complications due to aortic disease. Long-term prophylactic treatment is recommended if the underlying aortic disease cannot be surgically managed. Tranexamic acid is a potentially safe option to relieve bleeding tendency.