Robotic partial nephrectomy for renal tumors larger than 4 cm.

BACKGROUND: Minimally invasive partial nephrectomy (PN) is most commonly performed for renal tumors < or =4 cm in size. Robotic PN (RPN) for tumors >4 cm has not been assessed. OBJECTIVE: To evaluate the safety and feasibility of RPN for tumors >4 cm in the context of patients undergoing RPN for tumors < or =4 cm. DESIGN, SETTING, AND PARTICIPANTS: We reviewed data for 71 consecutive patients who underwent transperitoneal RPN at a tertiary care center between August 2007 and September 2009 by a single surgeon. Patients were stratified into two groups: 15 with tumors >4 cm on preoperative imaging (group 1) and 56 patients with tumors < or =4 cm (group 2). INTERVENTION: All patients underwent transperitoneal RPN by a single surgeon. MEASUREMENTS: Preoperative, perioperative, pathologic, and functional outcomes data were analyzed and compared between groups. We used chi(2) and student t tests for categorical and continuous variables, respectively. A p value <0.05 was considered statistically significant. RESULTS AND LIMITATIONS: Mean radiographic tumor size was 5.0 cm (4.1-7.9) for group 1 and 2.1cm (0.7-3.8) for group 2. No significant differences were found between groups for estimated blood loss, total operative time, hospital stay, complication rates, and change in estimated glomerular filtration rate. Patients with larger tumors had longer median warm ischemia times (25 vs 20 min; p=0.011). Limitations of our study include the retrospective nature the analysis, small sample size, and single-surgeon experience. CONCLUSIONS: In our initial experience, RPN for tumors >4 cm is safe and feasible, showing comparable outcomes to RPN for smaller tumors, although with longer warm ischemia times. Future studies with extended follow-up are necessary to determine the viability of RPN for large tumors as an effective form of treatment.

Effect of laparoscopic gastric bypass surgery on urinary incontinence in morbidly obese women.

BACKGROUND: Morbid obesity is an independent risk factor for urinary incontinence (UI) that tends to be underreported. A validated, reliable, self-administered, easy-to-use questionnaire was used to determine the effect of laparoscopic gastric bypass (LGB) surgery on UI in morbidly obese women. METHODS: We prospectively evaluated 470 morbidly obese women seeking bariatric surgery with the International Consultation on Incontinence Questionnaire Short Form. The International Consultation on Incontinence Questionnaire Short Form was given to female patients at their initial consultation and at 3 and 12 months after LGB to assess both UI symptoms and quality of life. Data are expressed as the mean +/- standard deviation. RESULTS: The preoperative prevalence of UI was 66% (n = 309) and included 21% urge, 33% stress, and 46% mixed UI. For the 58 patients with UI who underwent LGB and completed a follow-up International Consultation on Incontinence Questionnaire Short Form, a reduction occurred in the total symptom score from 7.6 +/- 4 preoperatively to 3.0 +/- 4 and 1.8 +/- 4 (P < .001) at 3 and 12 months after LGB, respectively. The corresponding quality-of-life scores improved from 3.2 +/- 3 to 1.0 +/- 2 and 0.4 +/- 2 (P < .001). The UI had resolved in 64% and improved overall in 92% of patients at 1 year after LGB. An improvement in UI was found within 3 months after LGB with as little as 30 lb of weight loss. CONCLUSION: UI is a common co-morbidity in the morbidly obese and was prevalent in two thirds of female patients presenting for bariatric surgery evaluation. LGB with resultant weight loss significantly improved the UI symptoms and quality of life.

Impact of previous inguinal hernia repair on transperitoneal robotic prostatectomy.

OBJECTIVE: Several investigators have noted that previous inguinal hernia repair with or without the use of prosthetic mesh might be a relative contraindication for open or laparoscopic radical prostatectomy due to the presence of adhesions and the difficulty of tissue dissection. We aimed to evaluate the impact of previous hernia repair on the performance and feasibility of robotic prostatectomy. MATERIALS AND METHODS: We performed a retrospective analysis of 354 patients who underwent robotic prostatectomy at our institution. The three patient groups were: 292 patients who had no prior hernia repair (group 1), 50 patients who had prior inguinal herniorrhaphy without the use of prosthetic mesh (group 2), and 12 patients who had prior inguinal herniorrhaphy with the use of prosthetic mesh. We compared operative time (surgeon console time), estimated blood loss, and operative complications (bladder, bowel, and/or vascular injuries) in the three groups. RESULTS: Patients with no prior herniorrhaphy (group 1), prior herniorrhaphy without mesh (group 2), and prior herniorrhaphy with mesh (group 3), had similar mean operating times (126.9 minutes, 129.3 minutes and 145.6 minutes, respectively) and similar mean estimated blood loss (152.5 ml, 140.6 ml, and 141.6 ml, respectively) during radical prostatectomy. However, compared to the group of patients who had no prior hernia repair, the group who had prior herniorrhaphy with the use of mesh had a significantly longer mean console operating time (145.6 versus 126.9 minutes, p = .012). CONCLUSION: Previous hernia surgery, with or without the use of prosthetic mesh, did not represent a significant barrier to the performance of transperitoneal robotic prostatectomy.