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1.
J Pers Assess ; 106(2): 145-155, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-37417686

RESUMO

We re-oriented the HEXACO personality dimensions to approximate the Big Five, using two measures of the Big Five as targets in a derivation sample and then in cross-validation samples. The HEXACO approximations of Big Five Agreeableness represented blends of HEXACO Agreeableness, Emotionality, and Honesty-Humility. The HEXACO approximations of Big Five Neuroticism represented blends of Emotionality with low Agreeableness and low Extraversion. The residual sixth dimension, unrelated to the Big Five, contrasted Honesty-Humility with HEXACO Agreeableness. We then examined, in additional samples, some correlates of the original and re-rotated HEXACO dimensions. In the original HEXACO factor space, Honesty-Humility was the strongest correlate of unethical behaviors (selfishness and cheating), participant age, and "assumed similarity" to a friend or partner. Upon re-rotation of the HEXACO factors, associations involving these variables were divided between Big Five Agreeableness and the residual sixth dimension. Sex differences were mainly associated with Emotionality but after re-rotation of the HEXACO factors were divided between Big Five Agreeableness and Neuroticism. We discuss the relative merits of the original and Big Five-targeted HEXACO dimensions with reference to the practical utility of Big Five Agreeableness and Neuroticism and the simplicity and theoretical interpretability of the original HEXACO factors.


Assuntos
Transtornos da Personalidade , Personalidade , Feminino , Humanos , Masculino , Neuroticismo , Inventário de Personalidade
2.
Sensors (Basel) ; 22(12)2022 Jun 09.
Artigo em Inglês | MEDLINE | ID: mdl-35746159

RESUMO

It is necessary to convert to automation in a tomato hydroponic greenhouse because of the aging of farmers, the reduction in agricultural workers as a proportion of the population, COVID-19, and so on. In particular, agricultural robots are attractive as one of the ways for automation conversion in a hydroponic greenhouse. However, to develop agricultural robots, crop monitoring techniques will be necessary. In this study, therefore, we aimed to develop a maturity classification model for tomatoes using both support vector classifier (SVC) and snapshot-type hyperspectral imaging (VIS: 460-600 nm (16 bands) and Red-NIR: 600-860 nm (15 bands)). The spectral data, a total of 258 tomatoes harvested in January and February 2022, was obtained from the tomatoes' surfaces. Spectral data that has a relationship with the maturity stages of tomatoes was selected by correlation analysis. In addition, the four different spectral data were prepared, such as VIS data (16 bands), Red-NIR data (15 bands), combination data of VIS and Red-NIR (31 bands), and selected spectral data (6 bands). These data were trained by SVC, respectively, and we evaluated the performance of trained classification models. As a result, the SVC based on VIS data achieved a classification accuracy of 79% and an F1-score of 88% to classify the tomato maturity into six stages (Green, Breaker, Turning, Pink, Light-red, and Red). In addition, the developed model was tested in a hydroponic greenhouse and was able to classify the maturity stages with a classification accuracy of 75% and an F1-score of 86%.


Assuntos
COVID-19 , Solanum lycopersicum , Humanos , Imagens, Psicoterapia
3.
Scand J Psychol ; 62(6): 887-894, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34562027

RESUMO

The HEXACO personality factors of Agreeableness-versus-Anger (A) and Honesty-Humility (H) are interpreted as two complementary aspects of reciprocal altruistic tendency. Here we consider several ways of representing the positive associations between the defining traits of A and of H, through common factor analysis of self-report HEXACO Personality Inventory-Revised (HEXACO-PI-R) facet scale scores (N ≈ 111,000). We describe orthogonal solutions that differ in the extent to which H facets show secondary loadings on A (and vice versa), as well as an oblique solution compatible with a higher-order "cooperativeness" factor. We discuss the psychological plausibility of these solutions, and we review research showing differential associations of several phenomena or outcomes with A and H. We conclude that the optimal representation of A/H trait associations is not yet known but that the value of separate A and H factor scales is well established.


Assuntos
Ira , Personalidade , Altruísmo , Análise Fatorial , Humanos , Inventário de Personalidade
4.
Front Psychiatry ; 12: 637029, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34122172

RESUMO

Background: In the clinical field, anger has generally been studied in terms of aggressive behavior. However, in Asians, anger suppression is more common than anger expression. Hwabyung is a culture-related anger syndrome in Korea and is known to occur due to the continued repression of anger. Investigating Hwabyung should lead to a better understanding of the multiple dimensions of anger. To explore Hwabyung patients' experiences and perspectives, a meta-aggregation approach was used to conduct a systematic review and a qualitative synthesis. Methods: A systematic search was conducted in MEDLINE/PubMed, EMBASE, Allied and Complementary Medicine Database (AMED), Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycARTICLES, and four Korean databases [Korean Medical Database (KMbase), Korean Studies Information Service System (KISS), National Digital Science Library (NDSL), and Oriental Medicine Advanced Searching Integrated System (OASIS)] in September 2020. Studies were included if they collected and analyzed qualitative data from Hwabyung patients. Qualitative research findings on the experiences and perspectives of Hwabyung patients in Korea were critically appraised and synthesized using the Joanna Briggs Institute methodology. Results: Seven eligible studies were included. The findings from those studies (i.e., theme or subtheme of qualitative research) were aggregated into categories (a group of similar findings) and synthesized findings (a group of categorized findings). Ultimately, 116 findings were aggregated into 15 categories. Finally, four synthesized findings were derived from the 15 categories: (i) anger arousal, (ii) blame, (iii) uncontrollable physical and emotional symptoms, and (iv) compromise and temporary coping. Conclusions: Patients with Hwabyung experience chronic anger through the complex cognitive processes involved in blame. Hwabyung negatively affects patients' physical, psychological, and social functions. Because Hwabyung patients feel as if they are losing control, due to emotional dysregulation and physical symptoms, professional support should be provided to facilitate their coping strategies. Further studies on Hwabyung can serve as a new model of pathological anger.

5.
Curr Opin Psychol ; 40: 51-55, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33011676

RESUMO

We review research on personality/religiousness associations, integrating earlier meta-analyses with recent large-sample online studies. We find that general religiousness shows small positive associations with broad personality factors (e.g. HEXACO Honesty-Humility, Big Five Agreeableness, Conscientiousness) and somewhat stronger positive associations with narrower personality traits involving prosocial tendencies (e.g. altruism, fairness, forgivingness). The link between religiousness and prosociality appears not to be an artifact of self-report method variance. Religious fundamentalism and spirituality show negative and positive associations, respectively, with the Openness factor of personality. Religiousness/personality associations tend to be weak in relatively non-religious countries but moderately strong in highly religious countries. The direction of causal influence between personality and religiousness is not yet clear. Religiousness shows modest negative associations with IQ and appears to be somewhat negatively related to scientific thinking.


Assuntos
Personalidade , Espiritualidade , Altruísmo , Humanos , Transtornos da Personalidade , Religião
6.
J Pers ; 88(6): 1075-1090, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32394462

RESUMO

OBJECTIVE: We examined sex differences in the HEXACO Personality Inventory-Revised (HEXACO-PI-R) factor- and facet-level scales and the associations of national sex differences in those scales with national characteristics such as wealth and gender equality. METHOD: HEXACO-PI-R self-reports were collected online from persons in 48 countries (N = 347,192). RESULTS: (1) Women averaged substantially higher than men in Emotionality and in Honesty-Humility, with (sample-unweighted) mean differences across countries of d = 0.84 and d = 0.37, respectively; (2) the HEXACO-PI-R factor scales showed a rather large multivariate sex difference (D > 1 in most countries), about 19% larger than found in similar samples with the Big Five personality factors, (3) some facet scales belonging to the same factor showed widely varying sex differences, (4) national-level sex differences in Emotionality were larger in wealthy and gender-egalitarian countries, replicating previous counterintuitive findings, but such a tendency was not clearly observed for Honesty-Humility, and (5) within several English-speaking countries, sex differences in Emotionality showed comparatively little ethnic variation, suggesting that societal characteristics may influence the size of sex differences in Emotionality. CONCLUSION: The HEXACO model of personality structure provides some new insights in understanding sex differences in personality at the individual and national levels.


Assuntos
Transtornos da Personalidade , Caracteres Sexuais , Feminino , Humanos , Masculino , Personalidade , Inventário de Personalidade , Autorrelato
7.
Artigo em Inglês | MEDLINE | ID: mdl-32256657

RESUMO

This study aimed to assess the costs, health status, and medical service satisfaction with Korean and conventional medicine use before and after surgery of patients visiting Korean medicine hospitals for postsurgical musculoskeletal pain. The study population comprised patients who visited KM hospitals for the first time between June and November 2017 for persistent or recurrent pain and discomfort after low back, neck, shoulder, or knee surgery. Various validated questionnaires were used to collect data. A total of 100 participants were enrolled, and the majority had undergone low back surgery (n = 82). The participants had received 1.3 ± 0.7 magnetic resonance imaging (MRI) examinations and 2.4 ± 2.8 X-rays before surgery. Conventional interventions used before surgery were physical therapy (43%), medications (34%), and injections (28%), in descending order, while 48% of patients reported having received acupuncture 51.3 ± 81.1 times. The mean satisfaction score for surgery was 5.5 ± 2.8 points based on a 9-point Likert scale, while that for KM-based interventions was 6.3 ± 1.7 points. With respect to health-related information, the mean scores were 6.0 ± 2.2 points on the Numeric Rating Scale (NRS), 0.6 ± 0.2 points on the 5-Level EuroQol-5 Dimension (EQ-5D-5L), and 15.3 ± 10.2 on Beck's Depression Index II (BDI-II). The mean score on the Oswestry Disability Index (ODI) in patients with low back pain was 40.1 ± 19.2 points. Work impairment, as measured using the Work Productivity and Activity Impairment Questionnaire: General Health (WPAI-GH), was 62.5 ± 47.8%, while activity impairment was 5.9 ± 2.6%. Participants tended to show low satisfaction regarding surgery and high preference for KM-based interventions. In particular, low back surgery patients reported high ODI scores, indicating high dysfunctional levels and poor prognosis after surgery. It can be inferred that it is therefore important to provide appropriate presurgical and postsurgical care for patients with musculoskeletal pain to improve pain, function, and quality of life.

8.
J Pers Assess ; 102(5): 714-726, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31184949

RESUMO

The HEXACO Personality Inventory-Revised (HEXACO-PI-R) has become one of the most heavily applied measurement tools for the assessment of basic personality traits. Correspondingly, the inventory has been translated to many languages for use in cross-cultural research. However, formal tests examining whether the different language versions of the HEXACO-PI-R provide equivalent measures of the 6 personality dimensions are missing. We provide a large-scale test of measurement invariance of the 100-item version of the HEXACO-PI-R across 16 languages spoken in European and Asian countries (N = 30,484). Multigroup exploratory structural equation modeling and confirmatory factor analyses revealed consistent support for configural and metric invariance, thus implying that the factor structure of the HEXACO dimensions as well as the meaning of the latent HEXACO factors is comparable across languages. However, analyses did not show overall support for scalar invariance; that is, equivalence of facet intercepts. A complementary alignment analysis supported this pattern, but also revealed substantial heterogeneity in the level of (non)invariance across facets and factors. Overall, results imply that the HEXACO-PI-R provides largely comparable measurement of the HEXACO dimensions, although the lack of scalar invariance highlights the necessity for future research clarifying the interpretation of mean-level trait differences across countries.


Assuntos
Inventário de Personalidade/normas , Psicometria/normas , Adulto , Comparação Transcultural , Feminino , Humanos , Masculino
9.
J Pers ; 87(6): 1103-1118, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30693514

RESUMO

OBJECTIVE: To examine the associations of religiousness with personality characteristics. METHOD: We obtained self-ratings of religiousness along with self-reports on the HEXACO Personality Inventory-Revised in a sample of nearly 200,000 online respondents. Respondents also indicated their religious affiliation, religiousness of upbringing, and political orientation; a subset of the respondents also indicated attitudes about immigration and foreign aid. RESULTS: Religiousness showed weak associations (|r|s < 0.15) with several HEXACO factors but somewhat stronger associations with the Fairness and Altruism facets (both rs > 0.20). On those facets, participants with the highest religiousness self-rating (7 on a 1-to-7 scale) averaged about 1 SD higher than did participants with the lowest religiousness self-rating. In addition, religiousness was negatively related to the Unconventionality facet among persons whose upbringing was very religious, but not among persons whose upbringing was very nonreligious. Religiousness/personality associations were generally quite similar within different religious affiliations (Hinduism, Islam, Judaism, Buddhism, and several branches of Christianity) but were stronger within relatively religious countries than within nonreligious countries. Despite the positive association of religiousness with the Altruism facet, religiousness was uncorrelated with pro-out-group attitudes (i.e., favoring multicultural immigration and foreign aid). CONCLUSION: The findings advance our understanding of religiousness/personality associations.


Assuntos
Inventário de Personalidade , Personalidade , Religião e Psicologia , Adulto , Altruísmo , Atitude , Feminino , Humanos , Masculino
10.
J Pers Assess ; 101(6): 567-573, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-29630400

RESUMO

We examined the ability of several Big Five measures to account for variance in HEXACO Personality Inventory-Revised (HEXACO-PI-R) scales and vice versa. Some Big Five measures accounted for more variance in HEXACO Honesty-Humility than did others, but these differences were largely offset by opposing differences in accounting for variance in HEXACO Agreeableness and Emotionality. As a consequence, the various Big Five measures showed similarly large overall deficiencies in accounting for HEXACO scale variance, relative to variance accounted for in Big Five scales by HEXACO-PI-R scales. The results imply that the use of Big Five instead of HEXACO scales entails a large loss of information, about equal to the amount that would be lost by discarding one of the Big Five scales.


Assuntos
Modelos Psicológicos , Inventário de Personalidade/normas , Personalidade , Adulto , Análise Fatorial , Feminino , Humanos , Masculino , Transtornos da Personalidade/diagnóstico , Psicometria , Reprodutibilidade dos Testes
11.
Soc Psychol Personal Sci ; 9(5): 516-520, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30220959

RESUMO

This article shows that the conclusion of Feldman et al.'s (2017) Study 1 that profane individuals tend to be honest is most likely incorrect. We argue that Feldman et al.'s conclusion is based on a commonly held but erroneous assumption that higher scores on Impression Management Scales, such as the Lie Scale, are associated with trait dishonesty. Based on evidence from studies that have investigated (1) self-other agreement on Impression Management Scales, (2) the relation of Impression Management Scales with personality variables, and (3) the relation of Impression Management Scales with objective measures of cheating, we show that high scores on Impression Management Scales are associated with high-instead of low-trait honesty when measured in low-stakes conditions. Furthermore, using two data sets that included an "I never swear" item, we show that profanity use is negatively related to other reports of HEXACO honesty-humility and positively related to actual cheating.

12.
J Behav Addict ; 7(2): 392-400, 2018 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-29846096

RESUMO

Background and aims Substantial research has examined the role of personality in disordered gambling. The predominant model in this work has been the five-factor model (FFM) of personality. In this study, we examined the personality correlates of gambling engagement and gambling severity using a six-dimensional framework known as the HEXACO model of personality, which incorporates FFM characteristics with the addition of honesty-humility. In addition, the potential mediating role of gambling motives in the personality and gambling severity relationship was explored. Methods A sample of undergraduate gamblers (n = 183) and non-gamblers (n = 143) completed self-report measures of the Problem Gambling Severity Index (PGSI) and the Gambling Motives Questionnaire-Financial, as well as self- and observer report forms of the HEXACO-100. Results Logistic regression results revealed that scores on honesty-humility were positively associated with non-gambling over gambling status. Furthermore, it was also found that honesty-humility, agreeableness, and conscientiousness were each uniquely associated with PGSI severity scores. The results of the mediational analyses suggest that each personality factor has different gambling motivational paths leading to PGSI gambling severity. Discussion and conclusions The findings of this study contribute to the literature on behavioral addictions by providing an increased understanding of individual personality factors associated with likelihood of gambling, overall gambling severity, and gambling motives. Ultimately, these findings suggest that the honesty-humility dimension may be a target for the prevention efforts against problematic gambling outcomes.


Assuntos
Jogo de Azar/psicologia , Motivação , Personalidade , Feminino , Humanos , Modelos Logísticos , Masculino , Modelos Psicológicos , Escalas de Graduação Psiquiátrica , Autorrelato , Índice de Gravidade de Doença , Adulto Jovem
13.
PLoS One ; 13(1): e0190472, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29293614

RESUMO

This study aimed to determine the factors influencing patients' choice of physician at the first visit through database analysis of a tertiary hospital in South Korea. We collected data on the first treatments performed by physicians who had treated patients for at least 3 consecutive years over 10 years (from 2003 to 2012) from the database of Seoul National University's affiliated tertiary hospital. Ultimately, we obtained data on 524,012 first treatments of 319,004 patients performed by 115 physicians. Variables including physicians' age and medical school and patients' age were evaluated as influencing factors for the number of first treatments performed by each physician in each year using a Poisson regression through generalized estimating equations with a log link. The number of first treatments decreased over the study period. Notably, the relative risk for first treatments was lower among older physicians than among younger physicians (relative risk 0.96; 95% confidence interval 0.95 to 0.98). Physicians graduating from Seoul National University (SNU) also had a higher risk for performing first treatments than did those not from SNU (relative risk 1.58; 95% confidence interval 1.18 to 2.10). Finally, relative risk was also higher among older patients than among younger patients (relative risk 1.03; 95% confidence interval 1.01 to 1.04). This study systematically demonstrated that physicians' age, whether the physician graduated from the highest-quality university, and patients' age all related to patients' choice of physician at the first visit in a tertiary university hospital. These findings might be due to Korean cultural factors.


Assuntos
Comportamento de Escolha , Sistemas de Informação Hospitalar , Centros de Atenção Terciária/organização & administração , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição de Poisson , República da Coreia
14.
Assessment ; 25(5): 543-556, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-27411678

RESUMO

Psychometric properties of the 100-item English-language HEXACO Personality Inventory-Revised (HEXACO-PI-R) were examined using samples of online respondents ( N = 100,318 self-reports) and of undergraduate students ( N = 2,868 self- and observer reports). The results were as follows: First, the hierarchical structure of the HEXACO-100 was clearly supported in two principal components analyses: each of the six factors was defined by its constituent facets and each of the 25 facets was defined by its constituent items. Second, the HEXACO-100 factor scales showed fairly low intercorrelations, with only one pair of scales (Honesty-Humility and Agreeableness) having an absolute correlation above .20 in self-report data. Third, the factor and facet scales showed strong self/observer convergent correlations, which far exceeded the self/observer discriminant correlations.


Assuntos
Inventário de Personalidade , Psicometria , Análise Fatorial , Humanos , Estudantes/psicologia
15.
J Sex Res ; 55(8): 951-961, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28276935

RESUMO

Previous research has examined self-identified sexual orientation in relation to self-reports on the Big Five personality factors. Here we extend this research by including asexuality as a fourth sexual orientation and by assessing the HEXACO personality factors, using self-report data from a large anonymous online sample (N ≈ 100,000). A large overlap was observed among all sexual orientation groups on all six HEXACO dimensions, but notable group differences also emerged. All nonheterosexual groups, particularly bisexual people, averaged higher in openness to experience than did heterosexuals. Heterosexual men averaged much lower in emotionality than heterosexual women, but only a small difference was observed between gay men and lesbians on this dimension. Asexual men and women averaged lower in extraversion and in some facets of emotionality (specifically, dependence and sentimentality) than did the other sexual orientation groups of the same sex. Results are discussed in relation to the different social realities that each sexual orientation group often experiences, along with the (gender-related) developmental influences hypothesized to underlie in part the origins of sexual orientation.


Assuntos
Bissexualidade/fisiologia , Heterossexualidade/fisiologia , Homossexualidade Feminina , Homossexualidade Masculina , Personalidade/fisiologia , Comportamento Sexual/fisiologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inventário de Personalidade , Adulto Jovem
16.
Am J Chin Med ; 45(8): 1573-1595, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29121797

RESUMO

The aim of this systematic review was to assess evidence from randomized controlled trials (RCTs) on the effectiveness and safety of acupuncture and electroacupuncture in patients with chronic neck pain. We searched nine databases including Chinese, Japanese and Korean databases through 30 July 2016. The participants were adults with chronic neck pain and were treated with acupuncture or electroacupuncture. Eligible trials were those with intervention groups receiving acupuncture and electroacupuncture with or without active control, and control groups receiving other conventional treatments such as physical therapy or medication. Outcomes included pain intensity, disability, quality of life (QoL) and adverse effects. For statistical pooling, the standardized mean difference (SMD) and its 95% confidence interval (CI) were calculated using a fixed-effects model. Sixteen RCTs were selected. The comparison of the sole acupuncture group and the active control group did not come out with a significant difference in pain (SMD 0.24, 95% CI [Formula: see text]0.27-0.75), disability (SMD 0.51, 95% CI [Formula: see text]0.01-1.02), or QoL (SMD [Formula: see text]0.37, 95% CI [Formula: see text]1.09-0.35), showing a similar effectiveness of acupuncture with active control. When acupuncture was added into the control group, the acupuncture add-on group showed significantly higher relief of pain in studies with unclear allocation concealment (SMD [Formula: see text]1.78, 95% CI [Formula: see text]2.08-[Formula: see text]1.48), but did not show significant relief of pain in studies with good allocation concealment (SMD [Formula: see text]0.07, 95% CI [Formula: see text]0.26-0.12). Significant relief of pain was observed when the sole electroacupuncture group was compared to the control group or electroacupuncture was added onto the active control group, but a lot of the results were evaluated to have low level of evidence, making it difficult to draw clear conclusions. In the result reporting adverse effects, no serious outcome of adverse event was confirmed. Acupuncture and conventional medicine for chronic neck pain have similar effectiveness on pain and disability when compared solely between the two of them. When acupuncture was added onto conventional treatment it relieved pain better, and electroacupuncture relieved pain even more. It is difficult to draw conclusion because the included studies have a high risk of bias and imprecision. Therefore better designed large-scale studies are needed in the future.


Assuntos
Terapia por Acupuntura , Eletroacupuntura , Cervicalgia/terapia , Doença Crônica , Bases de Dados Bibliográficas , Humanos , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento
17.
Biosci Biotechnol Biochem ; 81(10): 1883-1890, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28831862

RESUMO

In the current study, we examined the antioxidant and skin-whitening properties of Prunus mume extract (PME). The ability of PME to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals was investigated in vitro. At a concentration of 1000 µg/mL, PME neutralized >45% free radical activity. Cell viability assessment with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay revealed that at concentrations <1500 µg/mL, PME does not exert cytotoxic effects on murine B16 melanoma (B16) cells. Morphological analysis disclosed that melanin production is inhibited in B16 cells treated with 250 nM α-melanocyte-stimulating hormone (α-MSH) and PME. We conclude that fruit extracts of P. mume exert a skin-whitening effect by inhibiting melanin production via regulation of melanogenesis-associated protein expression in melanocytes.


Assuntos
Sequestradores de Radicais Livres/farmacologia , Melaninas/biossíntese , Melanoma Experimental/patologia , Extratos Vegetais/farmacologia , Prunus/química , alfa-MSH/farmacologia , Animais , Compostos de Bifenilo/química , Linhagem Celular Tumoral , Sobrevivência Celular/efeitos dos fármacos , Relação Dose-Resposta a Droga , Sequestradores de Radicais Livres/química , Sequestradores de Radicais Livres/isolamento & purificação , Melanossomas/efeitos dos fármacos , Melanossomas/metabolismo , Camundongos , Estresse Oxidativo/efeitos dos fármacos , Picratos/química , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificação
18.
J Pers Assess ; 99(2): 192-203, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27494804

RESUMO

Using self- and observer reports on the Personality Inventory for DSM-5 (PID-5) and the HEXACO Personality Inventory-Revised (HEXACO-PI-R), we identified for each inventory several trait dimensions (each defined by both self- and observer reports on the facet-level scales belonging to the same domain) and 2 source dimensions (each defined by self-reports or by observer reports, respectively, on all facet-level scales). Results (N = 217) showed that the source dimensions of the PID-5 were very large (much larger than those of the HEXACO-PI-R), and suggest that self-report (or observer report) response styles substantially inflate the intercorrelations and the alpha reliabilities of the PID-5 scales. We discuss the meaning and the implications of the large PID-5 source components, and we suggest some methods of controlling their influence.


Assuntos
Manual Diagnóstico e Estatístico de Transtornos Mentais , Transtornos da Personalidade/diagnóstico , Inventário de Personalidade , Personalidade , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Autorrelato
19.
Front Psychol ; 6: 1003, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26257669

RESUMO

People differ in the extent to which they identify with humans beyond their ingroup and with non-human living things. We refer to the former as the Connectedness to Humanity (CH) and to the latter as the Connectedness to Nature (CN). In a sample of 324 undergraduate students, CH and CN were operationalized using the Identification with All Humanity Scale (McFarland et al., 2012) and the CN Scale (Mayer and Frantz, 2004), respectively. These variables correlated moderately with each other (r = 0.44) and shared Openness to Experience and Honesty-Humility as their primary personality correlates. CN was found to play an important role in mediating the relationships between the two personality variables and some specific pro-environmental/pro-animal attitudes and ecological behaviors.

20.
J Ethnopharmacol ; 172: 219-26, 2015 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-26129938

RESUMO

ETHNOPHARMACOLOGICAL RELEVANCE: Gentiana scabra root extract (GS) is frequently prescribed as an internal remedy in traditional Korean medicine for treatment of diabetes mellitus. GS contains bitter iridoid glycosides including loganic acid, gentiopicrin, trifloroside, and rindoside. We previously reported that the intestinal bitter taste sensation stimulates GLP-1 secretion, and thereupon hypothesized that the blood glucose regulatory effect of GS is due to its GLP-1 secreting effect in enteroendocrine L cells. MATERIALS AND METHOD: We studied GLP-1 secreting effect of GS treatment and its cellular downstream mechanism in human enteroendocrine NCI-H716 cells using the G protein-coupled receptor (GPCR) pathway inhibitors. Intracellular calcium assay also demonstrated the signal transduction pathway stimulated by the GS treatment. Using db/db mice, we performed oral glucose tolerance test (OGTT) to examine the blood glucose lowering effect of GS administration. We also collected the mouse plasma during the OGTT to measure the GLP-1 and insulin levels. RESULT: We demonstrated dose-dependent GLP-1 secreting effect of GS on the NCI-H716 cells. The GLP-1 secreting effect of GS is mediated by the G protein ßγ-subunit and inositol triphosphate. Using db/db mice, we found that the effect of GS on lowering blood glucose is due to its GLP-1 secretion, and consequential insulinotropic effect. The chemical fingerprint of GS was obtained through a direct analysis in realtime mass spectrometry (DART-MS) and high-performance liquid chromatography (HPLC)/MS. Through the GLP-1 secretion study, we found that loganic acid, an iridoid glycoside, contributes to the GLP-1 secreting effect of GS. CONCLUSION: The findings of this study highlight the potential of exploiting the antidiabetic effect of GS on type 2 diabetes mellitus patients.


Assuntos
Glicemia/efeitos dos fármacos , Gentiana/química , Peptídeo 1 Semelhante ao Glucagon/metabolismo , Extratos Vegetais/farmacologia , Animais , Linhagem Celular , Cromatografia Líquida de Alta Pressão , Diabetes Mellitus Experimental/tratamento farmacológico , Diabetes Mellitus Tipo 2/tratamento farmacológico , Células Enteroendócrinas/efeitos dos fármacos , Células Enteroendócrinas/metabolismo , Teste de Tolerância a Glucose , Humanos , Hipoglicemiantes/isolamento & purificação , Hipoglicemiantes/farmacologia , Masculino , Espectrometria de Massas , Camundongos , Raízes de Plantas , Receptores Acoplados a Proteínas G/metabolismo , Transdução de Sinais/efeitos dos fármacos
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