1.
Genetics
; 172(2): 1369-72, 2006 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16322523
RESUMO
We show that mutants lacking either the phosphatase activator Rrd1 or the phosphatase Pph3 are resistant to rapamycin and that double mutants exhibit a synergistic response. This phenotype could be related to an inability of the mutants to degrade RNA polymerase II, leading to transcription of critical genes that sustain growth.