A Calibrated Force-Based Model for Mixed Traffic Simulation.

Virtual traffic benefits a variety of applications, including video games, traffic engineering, autonomous driving, and virtual reality. To date, traffic visualization via different simulation models can reconstruct detailed traffic flows. However, each specific behavior of vehicles is always described by establishing an independent control model. Moreover, mutual interactions between vehicles and other road users are rarely modeled in existing simulators. An all-in-one simulator that considers the complex behaviors of all potential road users in a realistic urban environment is urgently needed. In this work, we propose a novel, extensible, and microscopic method to build heterogeneous traffic simulation using the force-based concept. This force-based approach can accurately replicate the sophisticated behaviors of various road users and their interactions in a simple and unified manner. We calibrate the model parameters using real-world traffic trajectory data. The effectiveness of this approach is demonstrated through many simulation experiments, as well as comparisons to real-world traffic data and popular microscopic simulators for traffic animation.

ME-ACP: Multi-view neural networks with ensemble model for identification of anticancer peptides.

Cancer remains one of the most threatening diseases, which kills millions of lives every year. As a promising perspective for cancer treatments, anticancer peptides (ACPs) overcome a lot of disadvantages of traditional treatments. However, it is time-consuming and expensive to identify ACPs through conventional experiments. Hence, it is urgent and necessary to develop highly effective approaches to accurately identify ACPs in large amounts of protein sequences. In this work, we proposed a novel and effective method named ME-ACP which employed multi-view neural networks with ensemble model to identify ACPs. Firstly, we employed residue level and peptide level features preliminarily with ensemble models based on lightGBMs. Then, the outputs of lightGBM classifiers were fed into a hybrid deep neural network (HDNN) to identify ACPs. The experiments on independent test datasets demonstrated that ME-ACP achieved competitive performance on common evaluation metrics.