Effect of Nb-Ti Microalloyed Steel Precipitation Behavior on Hot Rolling Strip Shape and FEM Simulation.

Strip shape control is a hotspot and challenge in strip rolling, where the development trend of rolling technology is towards high strength, high toughness, and a large width-to-thickness ratio. The influence of material microstructure evolution on strip shape control is being increasingly emphasized. In this paper, a Nb-Ti microalloyed steel is taken as the research object. Thermodynamic and kinetic models focusing on the precipitation of the austenite phase are established to quantify the precipitation process. A coupled model of rolls and strips is built using ABAQUS 2022 software, where the precipitation strengthening model and high-temperature constitutive model are embedded into the finite element model (FEM) through subroutines. A two-dimensional alternating differential model is employed to acquire real-time temperature differences in the width direction of the strip. The effects of precipitation inclusion and exclusion on the strip crown under different operating conditions are compared and analyzed. The results indicate that as the temperature decreases, the strengthening effect increases, reaching around 40 MPa at temperatures above 1000 °C and 96.6 MPa at 800 °C. Furthermore, the inclusion of crown in the precipitation consideration is more sensitive to overall temperature changes, but as the strip width decreases, the sensitivity of crown to temperature decreases. The research findings of this paper provide guidance for improving strip shape control and reducing abnormalities during the rolling process.

RECK Gene Polymorphism is Associated with Susceptibility and Prognosis of Wilms' Tumor in Chinese Children.

BACKGROUND: Wilms' tumor (WT) is the most common malignant renal tumor in children. Previous studies suggested the reversion-inducing, cysteine-rich protein with Kazal motifs (RECK) down-regulation might have a role in numerous human cancers. The current study was done to investigate the associations of RECK single-nucleotide polymorphisms (SNPs) with the WT susceptibility in Chinese children. MATERIAL AND METHODS: We analyzed 2 SNPs (rs10972727 and rs11788747) in a total of 97 WT children and 194 healthy matched controls (1:2 ratio) by real-time PCR and PCR-RFLP genotyping analysis. RESULTS: We found that the G allele of rs11788747 in the RECK gene was significantly associated with WT in Chinese children (OR=0.7, 95% CI: 0.45-0.99; P=0.042); as with another SNP rs10972727, however, no statistically significant difference was detected. Further analysis showed there was also a statistically significant difference in genotype frequencies between terminal tumor stage (P=0.026) and metastatic groups (P=0.002). CONCLUSIONS: The present data indicate that there is a significant association between mutant G of rs11788747 in RECK and WT risk. G carriers with advanced tumor stage or with metastasis might have an increased risk of WT.

Prevalence of obesity among primary students between 2009 to 2014 in China: a meta-analysis.

BACKGROUND: In recent years, obesity has become the major public health problems worldwide. The detection rate of obesity is alarmingly rising among children and adolescents in China, whose population of 120 million are in range of obesity. It was estimated that 8% of her children are obese. METHODS: Publications between 2009 and 2014 on the obesity prevalence among primary school students in China were retrieved from PubMed, online Chinese periodical full-text databases of VIP, CNKI and Wanfang. Meta Analyst software was used to sum up and analyze the detection rates included in the previously retrieved literatures. RESULTS: After evaluation of the quality of the articles, 18 papers were finally included in our study, and the total sample sizes on the obesity investigation were 247547, in which 26466 were obesity. Meta-analysis findings showed that the pooled prevalence of obesity in primary school students is 10.0 %( 95% CI: 7.2%-13.5%). CONCLUSION: Our results indicated that the obesity prevalence status in China was still troublesome, for the situation will go worse if we currently fail to take effective and practical measures.

Introducción: En los últimos años, la obesidad se ha convertido en el principal problema de salud pública a nivel mundial. La tasa de detección de obesidad infantil está creciendo alarmantemente entre los niños y los adolescentes en China, cuya población de 120 millones se sitúa en el rango de obesidad. Se calculó que el 8% de los niños son obesos. Métodos: Se recopilaron publicaciones entre 2009 y 2014 sobre la prevalencia de obesidad entre los alumnos de primaria en China de PubMed, textos completos de bases de datos de periódicos chinos online de VIP, CNKI y Wanfang. Se empleó software de meta-análisis para resumir y analizar las tasas de detección incluidas en la bibliografía previamente obtenida. Resultados: Después de la evaluación de la calidad de los artículos, finalmente incluimos 18 artículos en nuestro estudio, y los tamaños de la muestra total en la investigación sobre obesidad fueron 247547, donde 26466 presentaron obesidad. Los resultados de los meta-análisis mostraron que la prevalencia de la obesidad en los alumnos de primaria es del 10,0% (IC del 95%: 7,2% - 13,5%). Conclusión: Nuestros resultados indican que la prevalencia de obesidad en China todavía supone un problema preocupante, dado que la situación será peor si no se toman medidas eficaces y prácticas.