Household carbon footprints of age groups in China and socioeconomic influencing factors.

China has a large fastest-aging population, which would reshape household consumption patterns and influence global CO2 emissions. This study examines global CO2 emissions driven by household consumption (i.e., household carbon footprints, HCFs) of 34 age groups in China's 30 provinces and uncovers relevant socioeconomic influencing factors. Results show that China's population aging (i.e., the proportion of the elderly population) is conducive to global CO2 emission reduction during 2011-2014. This trend is mainly due to the relatively lower per capita HCFs of the elderly (1.7 t in 2014). In contrast, the per capita HCFs of the youth group are higher (3.3 t in 2014), mainly affected by the large expenditure on residence and transportation & communication. In addition, the HCFs of all age groups have increased during 2011-2014. Per capita expenditure is the most significant driver of this increase. The decline in CO2 emission intensity makes the largest contribution to reducing the HCFs of the youth group. For the aged group, expenditure structure change is the largest contributor to HCFs reduction. These findings reveal the differentiated impacts of China's household consumption by age on global CO2 emissions. This study lays the scientific foundation for deriving amelioration policies and achieving emission reduction targets in the process of population aging.

Feasibility of Augmented Reality for Pediatric Giant Supratentorial Tumors: A Report of Three Cases.

Giant supratentorial brain tumors (GSBTs) in children are uncommon and extremely challenging entities unique to pediatric neurosurgery. Factors such as young patient age, need for urgent intervention, intraoperative blood loss, and ongoing raised intracranial pressure symptoms are examples of difficulties faced. Recently, there has been a growing body of literature on augmented reality (AR) in adult neurosurgery. In contrast, the use of AR in pediatric neurosurgery is comparatively less. Nonetheless, we postulate that AR systems will be helpful for understanding spatial relationships of complex GSBT anatomy for preoperative planning in a timely fashion. This study describes our experience in trialing AR as a potential tool for three cases of pediatric GSBTs. Overall, the AR platform offers our neurosurgical team excellent visuospatial insights for preoperative decision-making. However, we observe that substantial time is required to set up the AR system prior to each clinical case discussion by the neurosurgical team. In congruency with existing literature, our preliminary results report that there are still obstacles that need to be addressed before the technology can be seamlessly implemented into the clinical workflow for these time-sensitive childhood brain tumors. To our knowledge, this is the first study to report the potential use of AR for complex pediatric GSBT cases.

Construction of a methodology framework to characterize dynamic full-sector land-use carbon emissions embodied in trade.

The globally massive land-use changes associated with unprecedented urbanization rate are leading to prodigious quantities of carbon emissions. Nonetheless, the dynamics of land-use carbon emissions, particularly driven by supply-chain activities across all relevant industrial sectors, remain largely unexplored, especially in non-agricultural sectors. Here, we constructed a novel methodological framework to quantify full-sector land-use carbon emissions in Shenzhen, China, an international megacity grappling with acute land resource scarcity. Then, we integrated this framework with multiregional input-output analysis to uncover the multi-scale embodied land-use emissions propelled by Shenzhen's supply-chain activities. Our results indicate a marked increase in Shenzhen's embodied carbon emissions, approximately two orders of magnitude greater than its physical emissions, tripling during 2005-2018. Remarkably, non-agriculture sectors contributed 81.3-90.5 % of physical and 46.6-58.4 % of embodied land-use emissions. The land-use changes occurred outside Shenzhen accounted for 6.5-13.3 % of Shenzhen's total embodied land-use emissions. The sectoral analysis revealed a transition from traditional manufacturing (e.g., metallurgy, chemical products, textiles, wood products) in 2010-2015 to high-tech sectors (e.g., electronic equipment and other manufacture) in 2015-2018. This shift was primarily attributed to concurrent industry transfer actions, leading to aggressive changes in land-use emission intensity discrepancies within and outside Shenzhen. This study provides a scientific basis for designing effective strategies to mitigate land-use carbon emissions associated with supply-chain activities.

Decreasing resilience of China's coupled nitrogen-phosphorus cycling network requires urgent action.

The coupled nature of the nitrogen (N) and phosphorus (P) cycling networks is of critical importance for sustainable food systems. Here we use material flow and ecological network analysis methods to map the N-P-coupled cycling network in China and evaluate its resilience. Results show a drop in resilience between 1980 and 2020, with further decreases expected by 2060 across different socio-economic pathways. Under a clean energy scenario with additional N and P demand, the resilience of the N-P-coupled cycling network would suffer considerably, especially in the N layer. China's socio-economic system may also see greater N emissions to the environment, thus disturbing the N cycle and amplifying the conflict between energy and food systems given the scarcity of P. Our findings on scenario-specific synergies and trade-offs can aid the management of N- and P-cycling networks in China by reducing chemical fertilizer use and food waste, for example.

Spatial and Cross-Sectoral Transfer of Air Pollutant Emissions from the Fleet Electrification in China by 2030.

Fleet electrification shifts emission sources from the tailpipe to electricity generation and automotive supply chains subsequently, with emission transfer among regions. Such a spatial and cross-sectoral transfer of air pollutant emissions might embody uncertain environmental benefits spatially, which has not been comprehensively quantified, mainly due to the complexity of manufacturing processes of electric vehicle (EV) components (e.g., battery). We developed a hybrid life cycle assessment by combining inventory data of major processes and cross-sectoral input-output information and identified how China's EV deployment would influence the spatial redistribution of air pollutant emissions currently (2017) and in the future (2030). The results indicate that fleet electrification could readily reduce life cycle nitrogen oxides (NOx) and nonmethane volatile organic compound (NMVOC) emissions by 12-93%, and the reductions are estimated to be concentrated in major cities and urban agglomerations. However, increased demand for electricity and power battery production could increase PM2.5 and SO2 emissions in 17-55% of grids under all the scenarios, which emerge in coal-rich (e.g., Inner Mongolia, Shanxi) and industrial (e.g., Shandong, Henan, Jiangsu) provinces. By tracing the upstream, 31-55% of vehicle-cycle emissions are from deep supply chains but exhibit diverse sources. It suggests the necessity to relieve emissions leakage of fleet electrification by synchronizing effective environmental management across multiple sectors through EV supply chains.

Macrophages in head and neck squamous cell carcinoma: A bibliometric analysis.

INTRODUCTION: The tumor microenvironment in head and neck squamous cell carcinoma (HNSCC) is densely infiltrated by macrophages. Utilizing bibliometric analysis, the characteristics, hotspots for research, and research frontiers related to macrophages in HNSCC were reviewed. METHODS: The Web of Science Core Collection database was queried for relevant articles published from 2000 to 2022. VOSviewer and CiteSpace software were utilized to evaluate and visualize macrophage-related HNSCC research trends and hotspots. RESULTS: Assessment of original articles revealed that the annual number of publications regarding the role of macrophages in HNSCC has increased steadily over the past 23 years. China produced the most articles, whereas the United States had the highest number of citations and highest H-index. Wuhan University and Oral Oncology were the most productive affiliation and journal, respectively. The paper published by Bray et al in the CA-A Cancer Journal for Clinicians in 2018 had the greatest number of citations. The keywords "expression," "cancer," and "tumor-associated macrophages (TAMs)" occurred most frequently. CONCLUSIONS: This bibliometric investigation discovered that publications about macrophages in HNSCC are steadily increasing. The majority of studies focused on macrophage polarization, macrophage markers, and inflammation in the tumor microenvironment. Furthermore, our bibliometric analysis revealed that the immunosuppressive role of tumor-associated macrophages in the tumor microenvironment and resistance to therapy in HNSCC have recently received attention.

Multiperspective Decoupling Analyses between Global Embodied Carbon Chains and Global Value Chains.

Decoupling global economic growth from carbon emissions is essential for mitigating global climate change while maintaining continuous economic growth. Traditional production-side decoupling analysis alone is insufficient to capture the decoupling status between carbon emissions and the value added throughout global supply chains. This study investigates the decoupling status between value added and greenhouse gas (GHG) emissions during 1995-2019 from consumption and income perspectives. We find that the decoupling statuses of 17 regions (especially Russia, Australia, and Malta) show significant differences across multiple perspectives. For example, Malta's direct GHG emissions decreased with its GDP growth from a production perspective (i.e., achieved strong decoupling). However, its consumption-based GHG emissions increased with the growth of consumption-based value added (i.e., expansive negative decoupling). Moreover, most international pairs have not yet achieved strong decoupling from consumption and income perspectives. International multilateral cooperation is crucial for decoupling global GHG emissions from economic growth across global supply chains. This study provides insights into the decoupling between embodied GHG emissions and value added from consumption and income perspectives. The findings of this study can complement existing policies on global GHG emission mitigation and sustainable development.

Idiopathic subglottic stenosis with an inguinal hernia in children: A case report.

RATIONALE: Idiopathic subglottic stenosis is a fibrotic condition of unknown origin that results in blockage of the central airway in the subglottic region. It is widely acknowledged that subglottic stenosis is a relatively uncommon structural anomaly that is difficult to operate on and cure due to its anatomical location. Inguinal hernias are well-established to be prevalent in infants and youngsters. We present a case of subglottic stenosis in a child complicated with an inguinal hernia (IH). PATIENT CONCERNS: A 7-year-old female was admitted to our hospital with a 1-month history of progressive bulging in the left lower quadrant of the abdomen. She complained of no stomach discomfort, distension, or dyspnea, but her family reports that the patient usually wheezes during moderate exertion and has no family history of asthma or lung illness. However, for unclear reasons, the infant experienced shortness of breath following training. A chest CT scan was unremarkable. Below the glottis, a membranous stenosis was discovered. The stenosis beneath the glottis was discovered using dynamic laryngoscopy. DIAGNOSES: Idiopathic subglottic stenosis with an IH. INTERVENTIONS: An otorhinolaryngologist employed a carbon dioxide laser to eliminate the subglottic stenosis. Following successful intubation by the anesthesiologist, pediatric surgeons performed laparoscopic high ligation of the hernial sac. OUTCOMES: After 1 month, a repeat laryngoscopy revealed significant expansion of the subglottic stenosis, accounting for the improvement in respiratory symptoms. LESSONS: The present case raises awareness that surgeons should be more vigilant about respiratory complications in patients with an IH. Early diagnosis and treatment of respiratory illnesses are critical for patients undergoing endotracheal intubation.

A high spatial resolution dataset for methylmercury exposure in Guangdong-Hong Kong-Macao Greater Bay Area.

Dietary methylmercury (MeHg) exposure increases the risk of many human diseases. The Guangdong-Hong Kong-Macao Greater Bay Area (GBA) is the world's most populous bay area and people there might suffer a high risk of dietary MeHg exposure. However, there lacks a time-series high spatial resolution dataset for dietary MeHg exposure in the GBA. This study constructs a high spatial resolution (1 km × 1 km) dataset for dietary MeHg exposure in the GBA during 2009-2019. It first constructs the dietary MeHg exposure inventory for each county/district of the GBA, based on MeHg concentrations of foods (i.e., rice and fish in this study) and per capita rice and fish intake. Subsequently, this study spatializes the dietary MeHg exposure inventory at 1 km × 1 km scale, using gridded data for food consumption expenditure as the proxy. This dataset can describe the spatially explicit hotspots, distribution patterns, and variation trend of dietary MeHg exposure in the GBA. This dataset can support spatially explicit evaluation of MeHg-related health risks in the GBA.

Double-edged sword of technological progress to climate change depends on positioning in global value chains.

Technological progress (TP) is a double-edged sword to global climate change. This study for the first time reveals rebound and mitigation effects of efficiency-related TP in global value chains (GVCs) on greenhouse gas (GHG) emissions. The integrated effects of TP depend on the positioning of sectors in GVCs. The cost-saving TP in upstream sectors would stimulate downstream demand. This produces stronger rebound effects than mitigation potentials and leads to global GHG emission increments (e.g. TP in the gas sector of China and petroleum and coal products sector of South Korea). In contrast, sectors located in the trailing end of GVCs have greater potentials for GHG emission mitigation through TP, mainly due to the reduction of upstream inputs. (e.g. the construction sector of China and dwelling sector of the United States). Global GHG emissions and production outputs can be either a trade-off or a win-win relationship on account of TP than rebound effects, because TP in different sectors could possibly increase or decrease the emission intensity of GVCs. This study could recognize the most productive spots for GHG emission mitigation through efficiency-related TP. It provides a new perspective for international cooperation to promote global GHG emission mitigation.

Consumption in Non-Pastoral Regions Drove Three-Quarters of Forage-Livestock Conflicts in China.

Forage-livestock conflict (FLC) is a major anthropogenic cause of rangeland degradation. It poses tremendous threats to the environment owing to its adverse impacts on carbon sequestration, water supply and regulation, and biodiversity conservation. Existing policy interventions focus on the in situ FLCs induced by local production activities but overlook the role of consumption activities in driving FLCs. Here, we investigate the spatiotemporal variations in China's FLCs and the domestic final consumers at the county level by combining remote sensing data and multi-regional input-output model. Results show that during 2005-2015, China's pastoralism induced an average of 82 million tons of FLCs per year. Domestic final demand was responsible for 85-93% of the FLCs in China. There was spatiotemporal heterogeneity in domestic consumption driving China's FLCs. In particular, the final demand of non-pastoral regions was responsible for around three-quarters (74-79%) of the total FLCs throughout the decade. The rangeland-based livestock raising, agricultural and sideline product processing, and catering sectors are important demand-side drivers. These findings can support targeted demand-side strategies and interregional cooperation to reduce China's FLCs, thus mitigating rangeland degradation.

Impacts of Trans-Provincial Thermal Power Transmission on Air-Quality Recovery and Related Health Outcomes in China.

Trans-provincial thermal power transmission has become an important measure for optimizing power allocation and alleviating the mismatch between regional power production and consumption in China, however, leading to inter-regional redistribution of air pollution. Here, we investigated the impacts of thermal power transmission on air-quality recovery and related health outcomes in China. The results showed that the redistribution of air pollutant emissions contributed to air-quality improvements and health benefits in the eastern regions but to the opposite side in the western regions. On a national scale, trans-provincial thermal power transmission contributed to a change in air quality from slightly polluted to good conditions for a period of 9 days under the standard of 75 µg m-3, accounting for 1.8% of the total number of polluted days in 4 months of 2017 and promoting air-quality recovery in China. Furthermore, the recovery totally reduced the number of premature deaths (exposed to fine particulate matter, PM2.5) by 2392 persons (95% confidence interval: 1495-3124) in 2017. Owing to thermal power retrofits and stable power transmission structure, transmission network expansion during the last decade has not brought significant changes in its impacts on air pollution. However, the environmental inequity caused by thermal power transmission stimulates further attention on coordinating regional interests in air pollution control through various production-side and consumption-side measures.

Cascading impacts of global metal mining on climate change and human health caused by COVID-19 pandemic.

The coronavirus disease 2019 (COVID-19) pandemic has significantly disrupted global metal mining and associated supply chains. Here we analyse the cascading effects of the metal mining disruption associated with the COVID-19 pandemic on the economy, climate change, and human health. We find that the pandemic reduced global metal mining by 10-20% in 2020. This reduction subsequently led to losses in global economic output of approximately 117 billion US dollars, reduced CO2 emissions by approximately 33 million tonnes (exceeding Hungary's emissions in 2015), and reduced human health damage by 78,192 disability-adjusted life years. In particular, copper and iron mining made the most significant contribution to these effects. China and rest-of-the-world America were the most affected. The cascading effects of the metal mining disruption associated with the pandemic on the economy, climate change, and human health should be simultaneously considered in designing green economic stimulus policies.

A high spatial resolution dataset for anthropogenic atmospheric mercury emissions in China during 1998-2014.

China is the largest atmospheric mercury (Hg) emitter globally, which has been substantially investigated. However, the estimation of national or regional Hg emissions in China is insufficient in supporting emission control, as the location of the sources may have significant impacts on the effects of Hg emissions. In this concern, high-spatial-resolution datasets of China's Hg emissions are necessary for in-depth and accurate Hg-related studies and policymaking. Existing gridded datasets are constructed using population distribution as the proxy, which is limited as Hg emissions are closely related to energy consumption and economic processes. This study constructs a dataset of anthropogenic atmospheric Hg emissions in China gridded to a 1 km resolution during 1998-2014. This dataset is produced based on data of land uses, individual enterprises, roadmaps, and population, uncovering Hg emissions in agriculture, industries, services, and residents. This dataset can promote the reliability of Hg-related studies at a high spatial resolution. Moreover, this dataset can support spatially explicit Hg reduction of economic sectors.

COVID-19 from the perspective of otorhinolaryngology: An analysis of bibliometrics.

Background: Since it began in December 2019, the coronavirus disease 2019 (COVID-19) outbreak has not been completely contained. COVID-19 has attracted the interest of nations throughout the globe. The global coronavirus outbreak has had an especially devastating effect on otolaryngology. The virus is commonly associated with otorhinolaryngological symptoms. COVID-19 research is becoming more common in otorhinolaryngology. Although various studies on covid-19-related Otorhinolaryngology manifestations have been published, there has been no bibliometric analysis of these articles concentrating on COVID-19-related Otorhinolaryngology research. Methods: Original publications on Otolaryngological symptoms on COVID-19 were extracted from the Social Sciences Citation Index (SSCI) and the Science Citation Index-Expanded (SCI-E) databases in Clarivate Analytics' Web of Science Core Collection (WoSCC) between January 2020 and May 2022. CiteSpace and VOSviewer were utilized to detect and assess the research focus and trends in this field by extracting the country/region, institution, author, journal, references, and keywords related to this topic. Results: A total of 631 journals from 97 countries were included in the total of 1,528 articles. Most of the articles on this topic were published in the United States, which had the most citations and the highest H-index. Huazhong University of Science and Technology is the institution with the largest number of articles in the research of COVID-19-related Otorhinolaryngology diseases. Claire Hopkins was the most prolific author belonging to Guy's and St. Thomas' NHS Foundation Trust. Huang CL from Jin Yin-tan Hospital received the most citations among all authors. The most cited article was Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, which was created by Huang CL. Most of the studies relating to COVID-19 and Otorhinolaryngology diseases were published in the European Archives of Oto-Rhino-Laryngology. Conclusion: COVID-related research in the field of otorhinolaryngology has been studied in terms of descriptive quantitative metrics, which show that academics from around the world are working together to combat this pandemic.

Pollution exacerbates interregional flows of virtual scarce water driven by energy demand in China.

Existing studies on the virtual scarce water flows within the water-energy context focus on water quantity while largely ignoring water quality. This study improves the quantification method of scarce water uses by considering both blue water (representing water quantity) and grey water (indicating water quality). Based on a scarce-water extended multi-regional input-output model, we investigate the virtual scarce water flows driven by energy demand across 31 Chinese regions in 2012 and 2017. The results show that considering water quality provides new insights into the patterns of interregional flows of virtual scarce water driven by energy demand. The virtual integrated scarce water (VISW) flows, which consider both water quantity and quality, are 5 times the volume of virtual quantity-based scarce water (VQSW) flows. Moreover, certain regions (e.g., Hebei) are recognized as net VISW exporters, but are net importers in terms of VQSW. There are significant differences in the critical interregional pairs identified based on net VISW flows (e.g., Shandong-Zhejiang, and Shandong-Guangdong) and net VQSW flows (e.g., Heilongjiang-Guangdong, and Liaoning-Shaanxi). To reduce water scarcity based on the combined effect of both quantity and quality, the critical VISW interregional pairs should enhance cooperation through compensation payments and interregional technology transfer. This study highlights the importance of water quality in the assessment of virtual scarce water uses. Employing virtual scarce water as a policy tool to mitigate water scarcity might fail without the consideration of water quality.

The carbon emissions related to the land-use changes from 2000 to 2015 in Shenzhen, China: Implication for exploring low-carbon development in megacities.

Megacities exploit enormous amounts of lands from outside of the city boundary. However, there is a large knowledge gap in the impact of socioeconomic activities associated land-use changes on carbon emissions of megacities during the urbanization. In the current work, we combined the material-flow analysis, environmental extended input-output model, and land matrix data to construct a hybrid network framework. Such a framework was used to estimate the carbon emissions driving from trade between sectors and associated land use changes during 2000-2015 in Shenzhen, China. Results indicated that the total carbon emissions of Shenzhen had a growth rate of 262.7% from 2000 to 2010 and a declining rate of 17.6% from 2010 to 2015. This pattern is associated with large declining rates in the overall energy and carbon intensities by 53.8% and 63.2% during the period of 2000-2015. Meanwhile, embodied carbon emissions of Shenzhen kept rising by approximately twofold, accompanied by the increasing trends in the land-use related carbon emissions both inside and outside of city boundary. The land uses per unit GDP showed a dramatical decline by 85.7% and with a large contribution of the transportation and industrial land, and this caused a gradual increase in overall land-use related emissions with average growth rate of 7.1%. In addition, the land-use change related carbon emissions of the transportation and industrial land had a cumulative growth of 85%. As for the embodied land-use related carbon emissions, the dominated contributor was the Agriculture sector which drove an average of 0.13 MtC yr-1 emissions via importing agricultural products from outside of Shenzhen. This study provides a scientific foundation for corporately mitigate carbon emissions between megacities and their surrounding regions.

Human health and ecosystem impacts of China's resource extraction.

The throughput of materials fuels the economic process and underpins social well-being. These materials eventually return to the environment as waste or emissions. They can have significant environmental impacts throughout life cycle stages, such as biodiversity loss, adverse health effects, water stress, and climate change. China is the largest resource extractor globally, but the endpoint environmental impacts and the role of possible socioeconomic drivers associated with its resource extraction remain unclear. Here, we account for and analyze the two endpoint environmental impacts associated with China's resource extraction from 2000 to 2017 and quantify the relative contributions of various socioeconomic factors using structural decomposition analysis. The results show that the environmental impacts of China's resource extraction peaked in 2010. There was a significant decline from 2010 to 2017, in which human health damage decreased by 32.8 % and ecosystem quality damage decreased by 55.8 %. On the consumer side, the advancement in China's urbanization process led to an increase in the environmental impacts of urban residents' consumption, and the effect of investment on the environmental impacts decreased significantly after 2010. Decreases in the intensity of the environmental impacts in most sectors and improvements in production structure could reduce the impacts of resource extraction on human health and ecosystems.