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Toxicon ; 167: 76-81, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31170406

RESUMO

To understand phycotoxin contamination in shellfish in the sub-Arctic and Arctic areas, scanning for the presence of 13 hydrophilic and lipophilic toxin components each was by liquid chromatography tandem quadrupole mass spectrometry analysis in shellfish samples collected from the Northern Bering Sea and the Chukchi Sea in 2014. The results showed that shellfish collected in both areas werecontaminated to different extents. Saxitoxin (STX), decarbamoylsaxitoxin (dcSTX) and decarbamoylneosaxitoxin (dcNEO) were the most frequently detected hydrophilic components, with maximum concentrations of 90.1 µg/kg, 112.25 µg/kg and 23.09 µg/kg, respectively. Although gonyautoxins (GTXs) were only detected in 3 samples, they were the main contributors to overall toxicity of high-latitude samples, especially GTX1. For lipophilic toxins, spirolide-1 (SPX1) and yessotoxin (YTX) were present in all samples at low levels (< 7 µg/kg and < 50 µg/kg, respectively). Only 5 samples showed evidence of okadaic acid (OA) and dinophysistoxin-2 (DTX-2) at low concentrations, ranging from 0.42 µg/kg to 7.23 µg/kg and 3.03 µg/kg to 30.59 µg/kg, respectively. Notably, a high level of pectenotoxin-1 (PTX-1) at 467.40 µg/kg was found in the shellfish collected at the northernmost station, exceeding the safety regulation standard by nearly 3 times. For both lipophilic and hydrophilic toxins, contamination in shellfish in the sub-Arctic and the Arctic area may be much more widespread and severe than was previously thought. This study highlighted the need to monitor toxins in a wider variety of shellfish, especially economic or commercial species, and across a wider range of sub-Arctic and Arctic waters, as well as the potential sources of these toxins.


Assuntos
Contaminação de Alimentos/análise , Saxitoxina/análise , Frutos do Mar , Regiões Árticas , Cromatografia Líquida , Saxitoxina/análogos & derivados , Saxitoxina/química , Espectrometria de Massas em Tandem
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