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1.
Phys Rev Lett ; 125(6): 062001, 2020 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-32845675

RESUMO

The double-polarization observable E and helicity-dependent cross sections σ_{1/2}, σ_{3/2} have been measured for the photoproduction of π^{0} pairs off quasifree protons and neutrons at the Mainz MAMI accelerator with the Crystal Ball/TAPS setup. A circularly polarized photon beam was produced by bremsstrahlung from longitudinally polarized electrons and impinged on a longitudinally polarized deuterated butanol target. The reaction products were detected with an almost 4π covering calorimeter. The results reveal for the first time the helicity- and isospin-dependent structure of the γN→Nπ^{0}π^{0} reaction. They are compared to predictions from reaction models in view of nucleon resonance contributions and also to a refit of one model that predicted results for the proton and for the neutron target. The comparison of the prediction and the refit demonstrates the large impact of the new data.

2.
Phys Rev Lett ; 118(21): 212001, 2017 May 26.
Artigo em Inglês | MEDLINE | ID: mdl-28598665

RESUMO

The reactions γp→ηp and γp→η^{'}p are measured from their thresholds up to the center-of-mass energy W=1.96 GeV with the tagged-photon facilities at the Mainz Microtron, MAMI. Differential cross sections are obtained with unprecedented statistical accuracy, providing fine energy binning and full production-angle coverage. A strong cusp is observed in the total cross section for η photoproduction at the energies in the vicinity of the η^{'} threshold, W=1896 MeV (E_{γ}=1447 MeV). Within the framework of a revised ηMAID isobar model, the cusp, in connection with a steep rise of the η^{'} total cross section from its threshold, can only be explained by a strong coupling of the poorly known N(1895)1/2^{-} state to both ηp and η^{'}p. Including the new high-accuracy results in the ηMAID fit to available η and η^{'} photoproduction data allows the determination of the N(1895)1/2^{-} properties.

3.
Phys Rev Lett ; 117(13): 132502, 2016 Sep 23.
Artigo em Inglês | MEDLINE | ID: mdl-27715117

RESUMO

The double polarization observable E and the helicity dependent cross sections σ_{1/2} and σ_{3/2} were measured for η photoproduction from quasifree protons and neutrons. The circularly polarized tagged photon beam of the A2 experiment at the Mainz MAMI accelerator was used in combination with a longitudinally polarized deuterated butanol target. The almost 4π detector setup of the Crystal Ball and TAPS is ideally suited to detect the recoil nucleons and the decay photons from η→2γ and η→3π^{0}. The results show that the narrow structure previously observed in η photoproduction from the neutron is only apparent in σ_{1/2} and hence, most likely related to a spin-1/2 amplitude. Nucleon resonances that contribute to this partial wave in η production are only N 1/2^{-} (S_{11}) and N 1/2^{+} (P_{11}). Furthermore, the extracted Legendre coefficients of the angular distributions for σ_{1/2} are in good agreement with recent reaction model predictions assuming a narrow resonance in the P_{11} wave as the origin of this structure.

4.
Vopr Onkol ; 61(4): 571-4, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26571824

RESUMO

The article discusses the problem of radiation complications from normal tissues in patients after therapy with fast neutrons of 6.3 MeV. The methods of treatment using ozone technologies in patients with radiation reactions and skin lesions on the areas of irradiation after neutron and neutron-photon therapy have been worked out. Ozone therapy showed its harmlessness and increased efficiency of complex treatment of these patients.


Assuntos
Neoplasias/radioterapia , Nêutrons/efeitos adversos , Ozônio/uso terapêutico , Fótons/efeitos adversos , Lesões por Radiação/terapia , Adulto , Idoso , Neoplasias da Mama/radioterapia , Nêutrons Rápidos/efeitos adversos , Feminino , Neoplasias de Cabeça e Pescoço/radioterapia , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/radioterapia , Nêutrons/uso terapêutico , Fótons/uso terapêutico , Lesões por Radiação/etiologia , Resultado do Tratamento
5.
Vopr Onkol ; 61(4): 583-5, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26571827

RESUMO

The article is devoted to the problem of treatment of patients with locally advanced breast cancer recurrences as well as a study of neutron therapy influence on normal tissues and various critical organs. The use of fast neutrons of 6.3 MeV in these patients is often the only treatment option. A 6-year survival rate of patients without repeated signs of recurrent breast cancer after neutron and neutron-photon therapy is 92.2 ± 5.7%.


Assuntos
Neoplasias da Mama/radioterapia , Nêutrons Rápidos/uso terapêutico , Recidiva Local de Neoplasia/radioterapia , Adulto , Idoso , Neoplasias da Mama/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Dosagem Radioterapêutica , Análise de Sobrevida , Resultado do Tratamento
6.
Vopr Onkol ; 61(1): 149-53, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26016163

RESUMO

The article presents issues of the application of neutron therapy in the combined and radiation therapy for head and neck tumors. There were developed methods of neutron and neutron-photon therapy in pre- and postoperative periods as well as in stand-alone option in unresectable tumors. The data obtained clearly demonstrate the superiority of new ways over standard methods of treatment. Neutron therapy is satisfactorily tolerated and allows improving the results of combined and radiation therapy patients with malignant tumors of the head and neck.


Assuntos
Nêutrons Rápidos/uso terapêutico , Neoplasias de Cabeça e Pescoço/radioterapia , Fótons/uso terapêutico , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Terapia Neoadjuvante/métodos , Período Pós-Operatório , Radioterapia Adjuvante , Neoplasias da Glândula Tireoide/radioterapia , Resultado do Tratamento
7.
Phys Rev Lett ; 114(11): 112501, 2015 Mar 20.
Artigo em Inglês | MEDLINE | ID: mdl-25839263

RESUMO

The spin polarizabilities of the nucleon describe how the spin of the nucleon responds to an incident polarized photon. The most model-independent way to extract the nucleon spin polarizabilities is through polarized Compton scattering. Double-polarized Compton scattering asymmetries on the proton were measured in the Δ(1232) region using circularly polarized incident photons and a transversely polarized proton target at the Mainz Microtron. Fits to asymmetry data were performed using a dispersion model calculation and a baryon chiral perturbation theory calculation, and a separation of all four proton spin polarizabilities in the multipole basis was achieved. The analysis based on a dispersion model calculation yields γ(E1E1)=-3.5±1.2, γ(M1M1)=3.16±0.85, γ(E1M2)=-0.7±1.2, and γ(M1E2)=1.99±0.29, in units of 10(-4) fm(4).

8.
Phys Rev Lett ; 113(10): 102001, 2014 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-25238349

RESUMO

We present new data for the transverse target asymmetry T and the very first data for the beam-target asymmetry F in the γ[over →]p[over →]→ηp reaction up to a center-of-mass energy of W=1.9 GeV. The data were obtained with the Crystal-Ball/TAPS detector setup at the Glasgow tagged photon facility of the Mainz Microtron MAMI. All existing model predictions fail to reproduce the new data indicating a significant impact on our understanding of the underlying dynamics of η meson photoproduction. The peculiar nodal structure observed in existing T data close to threshold is not confirmed.

9.
Phys Rev Lett ; 112(24): 242502, 2014 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-24996085

RESUMO

Information on the size and shape of the neutron skin on (208)Pb is extracted from coherent pion photoproduction cross sections measured using the Crystal Ball detector together with the Glasgow tagger at the MAMI electron beam facility. On exploitation of an interpolated fit of a theoretical model to the measured cross sections, the half-height radius and diffuseness of the neutron distribution are found to be c(n)=6.70±0.03(stat.) fm and a(n)=0.55±0.01(stat.)(-0.03)(+0.02)(sys.) fm, respectively, corresponding to a neutron skin thickness Δr(np)=0.15±0.03(stat.)(-0.03)(+0.01)(sys.) fm. The results give the first successful extraction of a neutron skin thickness with an electromagnetic probe and indicate that the skin of (208)Pb has a halo character. The measurement provides valuable new constraints on both the structure of nuclei and the equation of state for neutron-rich matter.

10.
Phys Rev Lett ; 112(14): 142001, 2014 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-24765945

RESUMO

Precise angular distributions have been measured for the first time for the photoproduction of π0 mesons off neutrons bound in the deuteron. The effects from nuclear Fermi motion have been eliminated by a complete kinematic reconstruction of the final state. The influence of final-state-interaction effects has been estimated by a comparison of the reaction cross section for quasifree protons bound in the deuteron to the results for free protons and then applied as a correction to the quasifree neutron data. The experiment was performed at the tagged photon facility of the Mainz Microtron MAMI with the Crystal Ball and TAPS detector setup for incident photon energies between 0.45 and 1.4 GeV. The results are compared to the predictions from reaction models and partial-wave analyses based on data from other isospin channels. The model predictions show large discrepancies among each other and the present data will provide much tighter constraints. This is demonstrated by the results of a new analysis in the framework of the Bonn-Gatchina coupled-channel analysis which included the present data.

11.
Rev Sci Instrum ; 85(2): 02C314, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24593651

RESUMO

In this paper we present our cyclotron based neutron source with average energy 6.3 MeV generated during the 13.6 MeV deuterons interactions with beryllium target, neutron field dosimetry, and dosimetry of attendant gamma fields. We also present application of our neutron source for cancer treatment.


Assuntos
Ciclotrons/instrumentação , Neoplasias/radioterapia , Nêutrons/uso terapêutico , Universidades , Humanos , Radiometria , Fatores de Tempo
12.
Phys Rev Lett ; 112(2): 022501, 2014 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-24484003

RESUMO

We report the first large-acceptance measurement of polarization transfer from a polarized photon beam to a recoiling nucleon. The measurement pioneers a novel polarimetry technique, which can be applied to many other nuclear and hadron physics experiments. The commissioning reaction of 1H(γ, p)π0 in the range 0.4

13.
Radiats Biol Radioecol ; 54(5): 474-8, 2014.
Artigo em Russo | MEDLINE | ID: mdl-25775838

RESUMO

The present study is aimed to evaluate the frequency and severity of radiation-induced reactions in patients with stage T1-2N0-1M0 breast cancer, who received intraopeartive radiation therapy (IORT) in combination with external beam radiotherapy (EBRT). A small-size betatron producing 6 MeV electron beam was used for IORT. External beam radiotherapy was performed using Rokus and Theratron machines. Radiotherapy treatment was planned using a specially devised method to ensure acceptable levels of severity and frequency of radiation reactions. The patients were divided into 3 groups: the study (40 patients), control (88) and comparison (50) ones. Radiation-induced skin reactions in the study group ranged from erythema to moist desquamation and edema. Magnetic laser therapy was used to treat radiation-induced injuries. The applied method of estimating the total dose of IORT and EBRT was shown to provide the acceptable levels of severity and frequency of radiation reactions.


Assuntos
Neoplasias da Mama/radioterapia , Neoplasias Induzidas por Radiação/patologia , Lesões por Radiação/patologia , Dosagem Radioterapêutica , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Feminino , Humanos , Mastectomia Segmentar , Neoplasias Induzidas por Radiação/terapia
14.
Phys Rev Lett ; 111(6): 062004, 2013 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-23971564

RESUMO

A precision measurement of the differential cross sections dσ/dΩ and the linearly polarized photon asymmetry Σ≡(dσ⊥-dσ∥)/(dσ⊥+dσ∥) for the γp→π0p reaction in the near-threshold region has been performed with a tagged photon beam and almost 4π detector at the Mainz Microtron. The Glasgow-Mainz photon tagging facility along with the Crystal Ball/TAPS multiphoton detector system and a cryogenic liquid hydrogen target were used. These data allowed for a precise determination of the energy dependence of the real parts of the S- and all three P-wave amplitudes for the first time and provide the most stringent test to date of the predictions of chiral perturbation theory and its energy region of agreement with experiment.

15.
Phys Rev Lett ; 111(23): 232001, 2013 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-24476257

RESUMO

The photoproduction of η mesons off nucleons bound in 2H and 3He has been measured in coincidence with recoil protons and recoil neutrons for incident photon energies from threshold up to 1.4 GeV. The experiments were performed at the Mainz MAMI accelerator, using the Glasgow tagged photon facility. Decay photons from the η→2γ and η→3π0 decays and the recoil nucleons were detected with an almost 4π electromagnetic calorimeter combining the Crystal Ball and TAPS detectors. The data from both targets are of excellent statistical quality and show a narrow structure in the excitation function of γn→nη. The results from the two measurements are consistent, taking into account the expected effects from nuclear Fermi motion. The best estimates for position and intrinsic width of the structure are W=(1670±5) MeV and Γ=(30±15) MeV. For the first time precise results for the angular dependence of this structure have been extracted.

16.
Phys Rev Lett ; 103(5): 052002, 2009 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-19792489

RESUMO

Beam-helicity asymmetries have been measured at the MAMI accelerator in Mainz in the three isospin channels gamma[over -->]p-->pi(+)pi(0)n, gamma[over -->]p-->pi(0)pi(0)p, and gamma[over -->]p-->pi(+)pi(-)p. The circularly polarized photons, produced from bremsstrahlung of longitudinally polarized electrons, were tagged with the Glasgow magnetic spectrometer. Charged pions and the decay photons of pi(0) mesons were detected in a 4pi electromagnetic calorimeter which combined the Crystal Ball detector with the TAPS detector. The precisely measured asymmetries are very sensitive to details of the production processes and are thus key observables in the modeling of the reaction dynamics.

17.
Phys Rev Lett ; 100(13): 132301, 2008 Apr 04.
Artigo em Inglês | MEDLINE | ID: mdl-18517938

RESUMO

We present the first detailed measurement of incoherent photoproduction of neutral pions to a discrete state of a residual nucleus. The 12C(gamma,pi(0))(12)C*(4.4 MeV) reaction has been studied with the Glasgow photon tagger at MAMI employing a new technique which uses the large solid angle Crystal Ball detector both as a pi(0) spectrometer and to detect decay photons from the excited residual nucleus. The technique has potential applications to a broad range of future nuclear measurements with the Crystal Ball and similar detector systems elsewhere. Such data are sensitive to the propagation of the Delta in the nuclear medium and will give the first information on matter transition form factors from measurements with an electromagnetic probe. The incoherent cross sections are compared to two theoretical predictions including a Delta-hole model.

19.
Phys Rev Lett ; 94(16): 162001, 2005 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-15904214

RESUMO

Helicity-dependent total photoabsorption cross sections on the deuteron have been measured for the first time at ELSA (Bonn) in the photon energy range from 815 to 1825 MeV. Circularly polarized tagged photons impinging on a longitudinally polarized LiD target have been used together with a highly efficient 4pi detector system. The data around 1 GeV are not compatible with predictions from existing multipole analyses. From the measured energy range an experimental contribution to the GDH integral on the neutron of [33.9 +/- 5.5(stat) +/- 4.5(syst)] microb is extracted.

20.
Phys Rev Lett ; 93(3): 032003, 2004 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-15323817

RESUMO

For the first time we checked the fundamental Gerasimov-Drell-Hearn (GDH) sum rule for the proton experimentally in the photon energy range from 0.2-2.9 GeV with the tagged photon facilities at MAMI (Mainz) and ELSA (Bonn). New data of the doubly polarized total cross section difference are presented in the energy range from 1.6 to 2.9 GeV. The contribution to the GDH integral from 0.2-2.9 GeV yields [254+/-5(stat)+/-12(syst)] microb with negative contributions in the Regge regime at photon energies above 2.1 GeV. This trend supports the validity of the GDH sum rule.

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