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1.
iScience ; 27(5): 109616, 2024 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-38706845

RESUMO

Among various electrocatalysts, high-entropy alloys (HEAs) have gained significant attention for their unique properties and excellent catalytic activity in the hydrogen evolution reaction (HER). However, the precise synthesis of HEA catalysts in small sizes remains challenging, which limits further improvement in their catalytic performance. In this study, boron- and nitrogen-doped HEA porous carbon nanofibers (HE-BN/PCNF) with an in situ-grown dendritic structure were successfully prepared, inspired by the germination and growth of tree branches. Furthermore, the dendritic fibers constrained the growth of HEA particles, leading to the synthesis of quantum dot-sized (1.67 nm) HEA particles, which also provide a pathway for designing HEA quantum dots in the future. This work provides design ideas and guiding suggestions for the preparation of borated HEA fibers with different elemental combinations and for the application of dendritic nanofibers in various fields.

2.
Ultrastruct Pathol ; 48(3): 221-233, 2024 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-38619116

RESUMO

The endoplasmic reticulum(ER)is the largest membranous network serving as a region for protein, lipid and steroid synthesis, transport and storage. Detailed information about ER-cisternae, ER-tubules and rough endoplasmic reticulum (rER) is scarce in human blood cells. This study describes a series of giant inclusions and Auer bodies in promyeloblasts in six patients with acute promyelocytic leukemia (APL), by light microscopy, transmission electron microscopy (TEM) and cytochemical stains. TEM revealed that giant inclusions and pro-Auer bodies were associated with rER and surrounded by tubular structures composed of degenerated or redundant membrane in promyeloblasts, which corresponded with elements of the ER system. This paper reveals that in the promyeloblasts of APL, ER is the source of and transforms progressively into giant inclusions and Auer bodies.


Assuntos
Retículo Endoplasmático , Corpos de Inclusão , Leucemia Promielocítica Aguda , Microscopia Eletrônica de Transmissão , Humanos , Leucemia Promielocítica Aguda/patologia , Corpos de Inclusão/ultraestrutura , Masculino , Feminino , Retículo Endoplasmático/ultraestrutura , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Adolescente , Células Precursoras de Granulócitos/ultraestrutura , Células Precursoras de Granulócitos/patologia
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