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Colloids Surf B Biointerfaces ; 158: 182-189, 2017 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-28692873

RESUMO

The indiscriminate use of antibiotics and the emergence of resistant microorganisms have become a major challenge for the food industry. The purpose of this work was to microencapsulate the bacteriophage UFV-AREG1 in a calcium alginate matrix using microfluidic devices and to study the viability and efficiency of retention. The microcapsules were added to gel of propylene glycol for use as an antimicrobial in the food industry. The technique showed the number of the phage encapsulation, yielding drops with an average 100-250µm of diameter, 82.1±2% retention efficiency and stability in the gel matrix for 21days. The gel added to the microencapsulated phage showed efficiency (not detectable on the surface) in reducing bacterial contamination on the surface at a similar level to antimicrobial chemicals (alcohol 70%). Therefore, it was possible to microencapsulate bacteriophages in alginate-Ca and apply the microcapsules in gels for use as sanitizers in the food industry.


Assuntos
Dispositivos Lab-On-A-Chip , Alginatos/química , Bacteriófagos/química , Cápsulas/química , Ácido Glucurônico/química , Ácidos Hexurônicos/química , Tamanho da Partícula
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