RESUMO
Skin cancer is a major problem in the elderly. Squamous cell carcinoma (SCC), the second most common skin cancer, typically occurs in this age group. Despite a number of modalities readily available for treatment (depending on the tumor site, and depth of invasion) there remains the problem of individuals with multiple lesions who may be unsuitable for existing treatments for SCC, particularly surgery. Consequently, the search for novel treatments continues. To our knowledge, there are only 6 published reports of invasive SCC treated with 5-percent imiquimod cream.
Assuntos
Aminoquinolinas/administração & dosagem , Antineoplásicos/administração & dosagem , Carcinoma de Células Escamosas/tratamento farmacológico , Carcinoma de Células Escamosas/patologia , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/patologia , Idoso de 80 Anos ou mais , Aminoquinolinas/uso terapêutico , Antineoplásicos/uso terapêutico , Esquema de Medicação , Feminino , Humanos , Imiquimode , Invasividade Neoplásica , Pomadas , Resultado do TratamentoRESUMO
We report a case of secondary syphilis in a 54-year-old, bisexual, HIV positive man. Although syphilis is a well-known sexually-transmitted infection, it is not widely seen nowadays. However, a possible diagnosis of syphilis should not be overlooked in any individual, irrespective of HIV status.
Assuntos
Infecções por HIV/epidemiologia , Dermatopatias Papuloescamosas/diagnóstico , Sífilis/diagnóstico , Bissexualidade , Comorbidade , Humanos , Masculino , Pessoa de Meia-Idade , Dermatopatias Papuloescamosas/epidemiologia , Sífilis/epidemiologiaRESUMO
Five suture materials, chromic catgut, braided silk, Prolene, Teflon coated braided Dacron and Dexon have been examined morphologically for their effect on the submucosal collagen structure of the large intestine. The rougher surfaced materials, such as catgut, braided silk and Dexon, cause considerable damage to the submucosa on either side of an intestinal anastomosis. Because of this damage, it would appear that these sutures are more likely to jeopardize the integrity of an intestinal anastomosis.
Assuntos
Colo/ultraestrutura , Intestino Grosso/cirurgia , Técnicas de Sutura , Animais , Produtos Biológicos , Colágeno , Estudos de Avaliação como Assunto , Feminino , Mucosa Intestinal/ultraestrutura , Intestinos , Microscopia Eletrônica de Varredura , Poliésteres , Polietilenotereftalatos , Ácido Poliglicólico/uso terapêutico , Politetrafluoretileno , Ratos , Ovinos , TêxteisRESUMO
The morphologic structure of human, rat and mouse submucosa is similar. The strength, natural tension and extensibility of the submucosa can be readily interpreted form the physical properties of collagen and its structural arrangement as a pliable honeycomb. The perforations allow blood and lymph vessels to reach the mucosa.