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Eye Contact Lens ; 44 Suppl 2: S24-S28, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29064838

RESUMO

OBJECTIVES: To assess the antimicrobial effectiveness of multipurpose solutions in regard to the disinfection of silicone hydrogel contact lenses (CL) using a study of clinical bacterial isolates from ocular material. METHODS: Three multipurpose solutions (solution A: polyhexamethylene biguanide 0.00025 g/100 mL; solution B: polyquaternary-1 0.001% and myristamidopropyl dimethylamine 0.0006%; and solution C: polyaminopropyl biguanide 0.00013% and polyquaternary 0.0001%) were used as a 3-phase disinfection on silicone hydrogel CL contaminated with bacteria from clinical isolates that were divided into five groups (group 1: Pseudomonas aeruginosa; group 2: Staphylococcus aureus; group 3: Staphylococcus epidermidis; group 4: Streptococcus spp; and group 5: enterobacteria). RESULTS: No differences were observed between the 24- and 48-hr measurements in any of the samples, and the positivity of microorganisms in T0 was 100% for all solutions; it was 0% in T3. Therefore, only steps T1 (rubbing followed by rinsing) and T2 (rubbing followed by rinsing and immersion of CL into solution) were considered for analysis at the 24-hr measurement time. Throughout the phases, a decrease in the number of bacteria was observed, culminating in the elimination (no recovery) of all microorganisms in the three solutions. CONCLUSIONS: At the end of the proposed process, the tested solutions were effective.


Assuntos
Anti-Infecciosos/farmacologia , Soluções para Lentes de Contato/farmacologia , Lentes de Contato Hidrofílicas/microbiologia , Desinfecção/métodos , Infecções Oculares Bacterianas/prevenção & controle , Biguanidas/farmacologia , Humanos , Hidrogéis , Propilaminas/farmacologia , Pseudomonas aeruginosa/efeitos dos fármacos , Elastômeros de Silicone , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus epidermidis/efeitos dos fármacos
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