1.
Chem Commun (Camb)
; 57(83): 10919-10922, 2021 Oct 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34591048
RESUMO
Herein we describe a native mass spectromery protein-peptide model as a competent surrogate for the HOP-HSP90 protein-protein interaction (PPI), application of which led to the qualititive identification of two new peptides capable of in vitro PPI disruption. This proof of concept study offers a viable alternative for PPI inhibitor screening.