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J Dairy Sci ; 92(1): 369-74, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19109294

RESUMO

New platforms utilizing single nucleotide polymorphisms (SNP) offer operational advantages over the conventional microsatellite-based ones, making them a promising alternative for parentage exclusion. Through simulation and empirical data, a 40-SNP panel (where the minor allele frequency was 0.35 on average) was shown to be a comparable or better diagnostic tool than the current 14-microsatellite panel that is used to parentage test New Zealand dairy animals. The 40 SNP alone did not have sufficient power of exclusion to match more than 75% of the progeny to the correct sire and dam. Utilizing mating records and grouping progeny and dams by birth and calving dates, respectively, decreased the number of sire-dam combinations that each progeny was tested against and dramatically increased the utility of the SNP. These results highlight the importance of combining genotypes with on-farm data to maximize the ability to assign parentage in the New Zealand dairy herd.


Assuntos
Bovinos/genética , Indústria de Laticínios/métodos , Polimorfismo de Nucleotídeo Único/genética , Animais , Simulação por Computador , Feminino , Frequência do Gene , Genótipo , Masculino , Repetições de Microssatélites , Linhagem
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