Medicinal Plant Using Ground State Stabilization of Natural Antioxidant Curcumin by Keto-Enol Tautomerisation.

Curcumin is a medicinal agent that exhibits anti-cancer properties and bioactive pigment in Turmeric has a huge therapeutic value. It has a keto-enol moiety that gives rise to many of its chemical properties. A recent study has shown that keto-enol tautomerisation at this moiety is implicated the effect of curcumin. The tautomerisation of curcumin in methanol, acetone and acetonitrile are used in nuclear magnetic resonance (1H, 13C) spectroscopy. It was characterized using UV, IR and Raman spectral values. The molecular electrostatic potential surface of the Curcumin has been visualized in electropositive potential in the region of the CH3+ group and most electronegative potential in the two oxygen atom has very strong binding group. In the following, the modality of structural and thermo dynamical parameters, electrophilicity (ω), chemical potential (µ), chemical hardness (η) and electronic charge transfer confirms the local reactivity. The rate constant of tautomerisation of curcumin shows strong temperature dependence. Molecular electrostatic potential and Temperature dependence of various thermodynamic properties like [Formula: see text] is increase with increase in temperature for monomer and dimer of various electrical fields.

Electro therapy facial and laser skin whitening: Clients' perspective.

There are so many beauty salons in Metropolis who provide services to women exclusively [1]. These beauty salons depend mostly on electricity for their services to customers, without it there is no effective means of operation [2]. These beauty salons are definitely leading to women empowerment. The beauty salons are run by the women for women. Since they fall under the category of micro and small enterprises, these salons may avail so many financial and non- financial advantages from the Government of India. They also provide employment opportunities to the women employees. The development of such beauty salons rests on the clients' satisfaction on the provision of their services. Hence it is essential to measure the clients attitude towards the services offered by the beauty salons, especially electro therapy facial, laser skin whitening and laser hair removal treatments, which are coming under micro current treatment as a cosmetic tool.

An education management information system with simultaneous monitoring of stress stimulators for students Mental Health management.

Education Management Information System (EMIS) is a widely acceptable and developing technology within the Information Technology field. The advancement in technology in this century is being collaborated with scientific invention or explorer and information strengthening or development. This paper presents the results and experiences gained from applying students oriented EMIS for monitoring and managing mental health. The Mental Health of students depends on the acquiring adequate knowledge on basic concepts within a time period or academic schedule. It's obviously significance to evaluate and appraise the stress stimulators as a challenge or threat. The theoretical framework for the study was designed for analyzing the stress stimulators, academic performance and EMIS accessibility. The sample examined in this study was stratified random sample from 75 students specifically all engineering college in Dindigul District of Tamilnadu. The primary factor is the academic stress stimulators that form one module of EMIS for each of the key variable such as curriculum & instruction related stressors, placement related, teamwork related and assessment related. The Mental Health related stress stimulators namely curriculum & syllabus, placement related, assessment related and team work related have a significant influence on academic performance by students in various institution. The important factor leading to the EMIS application in monitoring stress stimulators is curriculum & syllabus related and assessment related.

A model of Occupational Safety and Health Management System (OSHMS) for promoting and controlling health and safety in textile industry.

BACKGROUND: The development of Occupational Safety and Health Management System in textile industry will rejuvenate the workers and energize the economy as a whole. In India, especially in Tamil Nadu, approximately 1371 textile business is running with the help of 38,461 workers under Ginning, Spinning, Weaving, Garment and Dyeing sectors. Textile industry of contributes to the growth of Indian economy but it fails to foster education and health as key components of human development and help new democracies. PURPOSE: The present work attempts to measure and develop OSHMS which reduce the hazards and risk involved in textile industry. Among all other industries textile industry is affected by enormous hazards and risk because of negligence by management and Government. It is evident that managements are not abiding by law when an accident has occurred. Managements are easily deceiving workers and least bothered about the Quality of Work Life (QWL). METHODOLOGY: A detailed analysis of factors promoting safety and health to the workers has been done by performing confirmatory factor analysis, evaluating Risk Priority Number and the framework of OHMS has been conceptualized using Structural Equation Model. The data have been collected using questionnaire and interview method. RESULT: The study finds occupation health for worker in Textile industry is affected not only by safety measure but also by technology and management. CONCLUSION: The work shows that difficulty in identifying the cause and effect of hazards, the influence of management in controlling and promoting OSHMS under various dimensions. One startling fact is existence of very low and insignificance correlation between health factors and outcome.

Development of model for assessing the acceptance level of users in rural healthcare system of Tamilnadu, India.

BACKGROUND: HMIS will incorporate a paradigm shift in health such as removing manual records and transformation of data through the complex structure of health departments in Tamilnadu. Thus developing a model of technology acceptance in HMIS contest is important and necessary in order to promote usage of the HMIS in rural health care system. OBJECTIVE: The papers purpose is to formulate a model of technology acceptance of Health Management Information System (HMIS) by generating and validating a research model that best describes rural health care workers usage behavior and behavior intention. METHODS: This research proposes a theoretical framework which is comprised of key determinants that influence usage behavior of HMIS together with moderator. It has been tested through different parametric test and confirmatory factor analysis. RESULTS: Data analysis shows that health workers innovativeness and voluntariness have a direct and positive influence on Technology Acceptance level and that the basic TAM hypotheses are fulfilled. HMIS usage behavior and behavior intention can be increased with factors that are effecting the successful implementation of HMIS when it remains high. CONCLUSIONS: This research enables health departments to know which aspects of their HMIS components and variables to improve. This shows that HMIS usage and health workers/staffs acceptance level are key tools in the success of HMIS. This research has seemed to be done at the right time and in the right place to the best of its kind.

Hepatoprotective activity of petroleum ether, diethyl ether, and methanol extract of Scoparia dulcis L. against CCl4-induced acute liver injury in mice.

OBJECTIVES: The present study was aimed at assessing the hepatoprotective activity of 1:1:1 petroleum ether, diethyl ether, and methanol (PDM) extract of Scoparia dulcis L. against carbon tetrachloride-induced acute liver injury in mice. MATERIALS AND METHODS: The PDM extract (50, 200, and 800 mg/kg, p.o.) and standard, silymarin (100 mg/kg, p.o) were tested for their antihepatotoxic activity against CCl4-induced acute liver injury in mice. The hepatoprotective activity was evaluated by measuring aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total proteins in serum, glycogen, lipid peroxides, superoxide dismutase, and glutathione reductase levels in liver homogenate and by histopathological analysis of the liver tissue. In addition, the extract was also evaluated for its in vitro antioxidant activity using 1, 1-Diphenyl-2-picrylhydrazyl scavenging assay. RESULTS: The extract at the dose of 800 mg/kg, p.o., significantly prevented CCl4-induced changes in the serum and liver biochemistry (P < 0.05) and changes in liver histopathology. The above results are comparable to standard, silymarin (100 mg/kg, p.o.). In the in vitro 1, 1-diphenyl-2-picrylhydrazyl scavenging assay, the extract showed good free radical scavenging potential (IC 50 38.9 +/- 1.0 mug/ml). CONCLUSIONS: The results of the study indicate that the PDM extract of Scoparia dulcis L. possesses potential hepatoprotective activity, which may be attributed to its free radical scavenging potential, due to the terpenoid constituents.

Radiobiological equivalent of low/high dose rate brachytherapy and evaluation of tumor and normal responses to the dose.

PURPOSE: The aim of this study was to compare the biological equivalent of low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy in terms of the more recent linear quadratic (LQ) model, which leads to theoretical estimation of biological equivalence. MATERIALS AND METHODS: One of the key features of the LQ model is that it allows a more systematic radiobiological comparison between different types of treatment because the main parameters alpha/beta and micro are tissue-specific. Such comparisons also allow assessment of the likely change in the therapeutic ratio when switching between LDR and HDR treatments. The main application of LQ methodology, which focuses on by increasing the availability of remote afterloading units, has been to design fractionated HDR treatments that can replace existing LDR techniques. RESULTS: In this study, with LDR treatments (39 Gy in 48 h) equivalent to 11 fractions of HDR irradiation at the experimental level, there are increasing reports of reproducible animal models that may be used to investigate the biological basis of brachytherapy and to help confirm theoretical predictions. This is a timely development owing to the nonavailability of sufficient retrospective patient data analysis. CONCLUSIONS: It appears that HDR brachytherapy is likely to be a viable alternative to LDR only if it is delivered without a prohibitively large number of fractions (e.g., fewer than 11). With increased scientific understanding and technological capability, the prospect of a dose equivalent to HDR brachytherapy will allow greater utilization of the concepts discussed in this article.

Pharmacognostical studies on leaves of ataiantia monophyia correa.

Leaves of Atalantia monophylla are used in chronic rheumatism and paralysis. The Pharmacognostical studies like histological characters, leaf constants, ash values and extractive values of leaves of Atalantia monophylla Corr were carried out. The preliminary phytochemical analysis were also carried out.

Some less known central nervous system depressant.

The present communication reports some medicinal plants which are used as Central Nervous System sedative agent in the traditional system of medicine.

Antibacterial activity of root extract of trianthema decandra.

Methanolic extract of Trianthema decandra was investigated for its antibacterial activity against staphylococcus aureus (NCIM 2079), Escherichia coli (NCIM 2065), Bacillus subtilis (NCIM 2063), Pseudomonas aeruginosa (NICIM 2036) and Proteus vulgaris (NICIM 2027) at 100 µg/disc using disc diffusion method. The extract showed significant antibacterial activity and were comparable to Chloramphenicol (30/ µg/disc). Our findings confirm the traditional therapeutic claims for this herb.