Multicentric sinus histicytosis (Rosai-Dorfman Disease): Computed tomography, magnetic resonance imaging findings.

Sinus histicytosis (Rosai-Dorfman disease) is a rare, benign granulomatous disease that typically presents with massive cervical lymphadenopathy. Extranodal involvement along with concomitant nodal disease occurs in about 43% of cases. We present a unique case of a 30-year-old male with cervical, retroperitoneal lymphadenopathy, associated with renal and pituitary sellar masses.

Rheumatoid arthritis: spectrum of computed tomographic findings in pulmonary diseases.

Rheumatoid arthritis (RA) is a common systemic disease that manifests as inflammatory arthritis of multiple joints. Interstitial lung disease (ILD) is the most common manifestation of rheumatoid lung disease. The ILDs associated with RA are diverse and it is very important for the general radiologist to differentiate one from another. There are many other pulmonary diseases apart from ILD. These are associated with a wide spectrum of morphologic changes with substantially different prognoses. The diagnosis of most of these diseases is by clinicoradiological correlation and some of them need pathologic correlation. High-resolution computed tomography helps to characterize and determine the extent of ILD in RA. When interpreting the high-resolution computed tomography of the chest in RA, the radiologist should be familiar with the findings in each entity and comment on activity of the disease, which helps in assessing the prognosis and need for active intervention. This pictorial essay reviews the spectrum of pulmonary diseases in RA and their differential diagnosis.

Palliative treatment in advanced hepatocellular carcinoma: has it made any difference?

Hepatocellular carcinoma (HCC) is a global health problem, the fifth most common cancer in the world. HCC occurs in a histologically abnormal liver due to underlying chronic liver disease resulting as a sequele of the chronic viral infections, hepatitis B and C. Since these two viral infections are endemic in Asia and Africa, more than 80% of cases are encountered in these regions. In India, a large proportion of the population is "at risk" for developing chronic liver disease and, therefore, HCC. Due to the lack of screening programmes in the country, the majority of HCC patients are diagnosed at an advanced stage of the disease, thus treatment remains a challenge. Palliative therapy forms the mainstay of treatment for this group of patients. The current era provides a plethora of options for the palliative management of HCC. This review concisely summarises the historical perspective and the current status of palliative treatment in advanced HCC.