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1.
Disaster Med Public Health Prep ; 16(1): 5-7, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-32867868

RESUMO

OBJECTIVE: Hurricane Sandy made landfall in New Jersey on October 29, 2012, resulting in widespread power outages and gasoline shortages. These events led to potentially toxic exposures and the need for information related to poisons/toxins in the environment. This report characterizes the New Jersey Poison Information and Education System (NJPIES) call patterns in the days immediately preceding, during, and after Hurricane Sandy to identify areas in need of public health education and prevention. METHODS: We examined NJPIES case data from October through December 2012. Most Sandy-related calls had been coded as such by NJPIES staff. Additional Sandy-related cases were identified by performing a case narrative review. Descriptive analyses were performed for timing, case frequencies, exposure substances, gender, caller site, type of information requests, and other data. RESULTS: The most frequent Sandy-related exposures were gasoline and carbon monoxide (CO). Gasoline exposure cases were predominantly males and CO exposure cases, females (P < 0.0001). Other leading reasons for Sandy-related calls were poison information, food poisoning/spoilage information, and water contamination. CONCLUSIONS: This analysis identified the need for enhanced public health education and intervention to improve the handling of gasoline and encourage the proper use of gasoline-powered generators and cleaning and cooking equipment, thus reducing toxic exposures.


Assuntos
Tempestades Ciclônicas , Venenos , Feminino , Gasolina , Humanos , Masculino , New Jersey/epidemiologia , Areia
2.
J Expo Sci Environ Epidemiol ; 29(2): 172-182, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30482936

RESUMO

INTRODUCTION: Per and polyfluoroalkyl substances (PFAS), including perfluorononanoic acid (PFNA) and perfluorooctanoic acid (PFOA), were detected in the community water supply of Paulsboro New Jersey in 2009. METHODS: A cross-sectional study enrolled 192 claimants from a class-action lawsuit, not affiliated with this study, who had been awarded a blood test for 13 PFAS. Study participants provided their blood test results and completed a survey about demographics; 105 participants also completed a health survey. Geometric means, 25th, 50th, 75th, and 95th percentiles of exposure of PFNA blood serum concentrations were compared to that of the 2013-2014 NHANES, adjusted for reporting level. Associations between PFNA, PFOA, PFOS, and PFHxS and self-reported health outcomes were assessed using logistic regression. RESULTS: PFNA serum levels were 285% higher in Paulsboro compared with U.S. residents. PFNA serum levels were higher among older compared with younger, and male compared to female, Paulsboro residents. After adjustment for potential confounding, there was a significant association between increased serum PFNA levels and self-reported high cholesterol (OR: 1.15, 95% CI: 1.02, 1.29). DISCUSSION/CONCLUSION: Further investigation into possible health effects of PFAS exposure in Paulsboro and other community settings is warranted. Since exposure has ceased, toxicokinetics of PFAS elimination should be explored.


Assuntos
Ácidos Alcanossulfônicos/sangue , Caprilatos/sangue , Poluentes Ambientais/sangue , Fluorocarbonos/sangue , Poluição Química da Água/análise , Abastecimento de Água/normas , Adulto , Biomarcadores/sangue , Caprilatos/economia , Estudos Transversais , Feminino , Fluorocarbonos/economia , Inquéritos Epidemiológicos , Humanos , Masculino , New Jersey , Inquéritos Nutricionais , Autorrelato , Poluição Química da Água/efeitos adversos
3.
Public Health Rep ; 133(3): 266-273, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29653060

RESUMO

OBJECTIVES: Extreme weather events require extensive tree removal and disposal, tasks associated with severe injury risks among workers and residents. To help understand the risks of such activities, we evaluated the impact of a large and destructive storm (Hurricane Sandy in 2012) on the incidence of tree-related injuries. METHODS: We searched chief-complaint text fields for patients aged 18-65 from 2011-2014 emergency department visit records submitted by New Jersey hospitals through the state-based syndromic surveillance system. Tree-related keywords (eg, saw, branch, wood chip, woodchip, tree) identified possible injuries that we then reviewed to exclude unrelated cases and classify mechanisms of tree-related injury. We used Poisson regression analysis to evaluate changes in the rates of probable tree-related injuries, adjusting for total emergency department visits and seasonal variation. RESULTS: We identified 698 probable tree-related injuries from 2011-2014 among patients aged 18-65, including 104 (14.9%) falls, 241 (34.5%) machine-related injuries, 311 (44.6%) struck-by injuries, and 42 (6.0%) other tree-related injuries. Tree-related injuries increased significantly in the quarter immediately after Hurricane Sandy (November 2012-January 2013) compared with the same quarter the year before (rate ratio [RR] = 1.67; 95% confidence interval [CI], 1.13-2.47) and the year after (RR = 2.47; 95% CI, 1.62-3.78) Hurricane Sandy, especially for struck-by injuries compared with the year before (RR = 2.74; 95% CI, 1.47-5.12) and the year after (RR = 4.17; 95% CI, 2.09-8.32) Hurricane Sandy. More than one-third of the injuries (33.4%) involved chainsaws. CONCLUSIONS: A major hurricane was associated with an increase in tree-related injuries in emergency departments, especially for mechanisms consistent with handling downed and damaged trees. Further research should confirm these findings and evaluate opportunities for preventing tree-related injuries.


Assuntos
Tempestades Ciclônicas/estatística & dados numéricos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Traumatismos Ocupacionais/epidemiologia , Árvores , Acidentes por Quedas/estatística & dados numéricos , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , New Jersey/epidemiologia
4.
Am J Ind Med ; 61(5): 361-371, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29516531

RESUMO

BACKGROUND: Given predictions that climate change will lead to an increase in severe storms, it is important to more fully understand the risks experienced by workers charged with the cleanup and removal of storm damaged trees. These hazards have received little attention in the occupational safety and health literature. METHODS: This paper is based on semi-structured interviews with 23 stakeholders involved in the Hurricane Sandy cleanup effort. RESULTS: Interview participants identified at risk sectors, gaps in training and preparedness, and raised particular concerns about storm downed trees, electrical hazards, and fatigue and suggested steps to reduce these hazards. CONCLUSIONS: Stakeholders' observations about storm response suggest directions for improving the health and safety of this critical workforce.


Assuntos
Acidentes de Trabalho/prevenção & controle , Tempestades Ciclônicas , Exposição Ocupacional/prevenção & controle , Gestão da Segurança/métodos , Árvores , Humanos , Entrevistas como Assunto , New England , Exposição Ocupacional/efeitos adversos , Saúde Ocupacional , Participação dos Interessados
5.
J Occup Environ Med ; 59(10): e164-e171, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28991808

RESUMO

INTRODUCTION: Psychosocial hazards in the workplace may adversely impact occupational and general health, including injury risk. METHODS: Among 16,417 adult workers in the 2010 National Health Interview Survey Occupational Health Supplement, weighted prevalence estimates were calculated for work-related injuries (WRI) and any injuries. The association between injury and psychosocial occupational hazards (job insecurity, work-family imbalance, hostile work environment) was assessed adjusting for sociodemographic and occupational factors. RESULTS: WRI prevalence was 0.65% (n = 99); any injury prevalence was 2.46% (n = 427). In multivariable models job insecurity, work-family imbalance, and hostile work environment were each positively associated with WRI prevalence (odds ratio [OR]: 1.60, 95% CI: 0.97-2.65; OR: 1.69, 95% CI 0.96-2.89; and 2.01, 95% CI 0.94-4.33, respectively). CONCLUSIONS: Stressful working conditions may contribute to injuries. There is need for ongoing surveillance of occupational psychosocial risk factors and further study of their relationship with injury.


Assuntos
Traumatismos Ocupacionais/etiologia , Local de Trabalho/psicologia , Adolescente , Adulto , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional/efeitos adversos , Exposição Ocupacional/estatística & dados numéricos , Traumatismos Ocupacionais/epidemiologia , Psicologia , Fatores de Risco , Estados Unidos/epidemiologia , Equilíbrio Trabalho-Vida/estatística & dados numéricos , Local de Trabalho/estatística & dados numéricos , Adulto Jovem
6.
Disaster Med Public Health Prep ; 10(3): 394-404, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-27080323

RESUMO

OBJECTIVE: We aimed to evaluate the occurrence of work-related injuries after Hurricane Sandy potentially related to response and recovery. METHODS: Emergency and hospital discharges (patients aged 18-65 years) with a diagnosis of unintentional injury were obtained from the New Jersey Department of Health. Work-related injuries were identified as those with a workers' compensation payer or other work-related codes. Counties were categorized as high-, medium-, or low-impact areas. Poisson regression analysis was used to compare the rate of work-related injury the year following Sandy landfall with the 3 previous years. RESULTS: Total work-related injuries declined the week immediately after Sandy (rate ratio [RR]: 0.85; 95% confidence interval [CI]: 0.69-1.05) and no overall increase was found in the year after Hurricane Sandy. However, high-impact counties showed an elevated risk of work-related injuries in the first and third quarters after Hurricane Sandy among men, especially for blacks and Hispanics. The greatest excesses occurred in the third quarter after the storm, May to July, for falls (RR: 1.30; 95% CI: 1.08-1.57), cut/pierce injuries (RR: 1.24; 95% CI: 1.09-1.40), struck-by injuries (RR: 1.17; 95% CI: 1.02-1.34), and overexertion (RR: 1.26; 95% CI: 1.10-1.44). CONCLUSIONS: Hospital data suggested an increase in injuries associated with rebuilding and recovery rather than with initial response. Future efforts aimed at prevention should evaluate the mechanisms and circumstances of injury in more detail. (Disaster Med Public Health Preparedness. 2016;10:394-404).


Assuntos
Tempestades Ciclônicas/estatística & dados numéricos , Traumatismos Ocupacionais/epidemiologia , Traumatismos Ocupacionais/etiologia , Acidentes/estatística & dados numéricos , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , New Jersey/epidemiologia
7.
Am J Med Genet A ; 167A(5): 1071-81, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25711982

RESUMO

A small number of population-based studies have examined sex differences among infants with birth defects. This study presents estimates of sex ratio for both isolated cases and those with multiple congenital anomalies, as well as by race/ethnicity. Male-female sex ratios and their 95% confidence intervals were calculated for 25,952 clinically reviewed case infants included in the National Birth Defects Prevention Study (1997-2009), a large population-based case-control study of birth defects. The highest elevations in sex ratios (i.e., male preponderance) among isolated non-cardiac defects were for craniosynostosis (2.12), cleft lip with cleft palate (2.01), and cleft lip without cleft palate (1.78); the lowest sex ratios (female preponderance) were for choanal atresia (0.45), cloacal exstrophy (0.46), and holoprosencephaly (0.64). Among isolated cardiac defects, the highest sex ratios were for aortic stenosis (2.88), coarctation of the aorta (2.51), and d-transposition of the great arteries (2.34); the lowest were multiple ventricular septal defects (0.52), truncus arteriosus (0.63), and heterotaxia with congenital heart defect (0.64). Differences were observed by race/ethnicity for some but not for most types of birth defects. The sex differences we observed for specific defects, between those with isolated versus multiple defects, as well as by race/ethnicity, demonstrate patterns that may suggest etiology and improve classification.


Assuntos
Anormalidades Múltiplas/genética , Anormalidades Congênitas/genética , Razão de Masculinidade , Anormalidades Múltiplas/epidemiologia , Anormalidades Múltiplas/fisiopatologia , Anormalidades Congênitas/epidemiologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino
8.
Occup Environ Med ; 70(11): 774-81, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23839661

RESUMO

OBJECTIVES: This study evaluated multiple blood lead measures collected over time and assessed differences arising from exposure and testing variability. METHODS: Blood lead data was used to compare individuals from manufacturing and construction occupational cohorts. Trends of blood lead levels (BLLs) over time were analysed using mixed model analysis. Random selection of BLL values was used to determine the improvement in the precision of mean BLL estimates as the number of tests increased. RESULTS: From 2003-2007, there were 619 manufacturing and 657 construction workers with more than one blood lead test reported. Construction workers had much more variability in their blood lead trends. They also tended to have less frequent follow-up blood tests compared with manufacturing workers. Both occupational cohorts had persistent BLLs that resulted in many workers with chronically high blood lead values (>25 µg/dL). Approximately 11.2% of construction workers and 34.8% of manufacturing workers with an initial blood lead test above 25 µg/dL remained above this blood level through the study period. The precision in the mean BLL estimates increased more substantially for construction workers when compared with manufacturing workers as the number of blood lead tests per worker increased. CONCLUSIONS: This study confirmed differences in the pattern of blood lead tests and the resulting trends for manufacturing compared with construction workers. It also suggested that the number of blood lead tests performed on a worker is an important consideration in the assessment of a worker's mean blood lead estimate, and this is particularly true for workers with highly variable exposures.


Assuntos
Indústria da Construção , Indústrias , Intoxicação por Chumbo/sangue , Chumbo/sangue , Doenças Profissionais/sangue , Exposição Ocupacional/análise , Humanos
9.
Workplace Health Saf ; 60(9): 401-9; quiz 410, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22938811

RESUMO

Investigations of young workers, including limited surveys in supervised school settings, suggested their elevated injury risk. This study identified factors contributing to cuts-lacerations among adolescents in New Jersey secondary school career, technical, and vocational education programs. Of 1,772 injuries reported between December 1, 1998, and September 1, 2010, 777 (44%) were cuts-lacerations; analyses focused on 224 reports (n = 182 post-exclusions) submitted after fall 2005 in three career groups-Food, Hospitality & Tourism (FH&T) (n = 71), Manufacturing & Construction (M&C) (n = 84), and Automotive & Transportation (A&T) (n = 27). Most students were "struck by" tools or hard surfaces (n = 93, 51%); 63 cuts were from knives in FH&T. In M&C, most cuts-lacerations were caused by hand-held tools (n = 18) and being "struck against/by" or "caught between hard surfaces" (n = 19). Males reported more cuts-lacerations (n = 145), most commonly among 11th graders (n = 54) and ages 16 to 17 years (n = 79). Fingers (n = 117) were most often injured, usually by cutting tools (n = 83). Training, supervision, and appropriate equipment, and further assessments of "struck by" and "pinch point" hazards, are needed.


Assuntos
Lacerações/epidemiologia , Instituições Acadêmicas/estatística & dados numéricos , Estudantes/estatística & dados numéricos , Educação Vocacional/estatística & dados numéricos , Adolescente , Causalidade , Feminino , Humanos , Masculino , New Jersey/epidemiologia , Adulto Jovem
10.
New Solut ; 22(3): 365-86, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22967368

RESUMO

Latino day laborers often work at dangerous construction sites with little power to change conditions. We describe the development, implementation, and early-stage results of a program to train immigrant day laborers as safety liaisons. These are construction workers prepared to recognize and respond to health and safety hazards. Based in Newark, NJ, the project involves collaboration between New Labor, a membership-based worker center, and university researchers and labor educators. Safety liaisons undergo training and receive ongoing support for their roles. Both qualitative and quantitative data are collected to monitor progress. Although lacking in formal authority, safety liaisons have prompted improvements at specific sites, filed OSHA complaints, and developed a local worker council. Participatory training methods, opportunities for leadership outside the classroom, and participation in project planning have strengthened liaisons' effectiveness, leadership skills, and commitment. The safety liaison approach could be adapted by worker centers and their partner organizations.


Assuntos
Indústria da Construção , Emigrantes e Imigrantes , Capacitação em Serviço/métodos , Saúde Ocupacional , Pesquisa Participativa Baseada na Comunidade , Emprego , Hispânico ou Latino , Humanos , New Jersey , Exposição Ocupacional/efeitos adversos , Estudos de Casos Organizacionais , Estados Unidos , United States Occupational Safety and Health Administration
11.
Birth Defects Res A Clin Mol Teratol ; 91(2): 93-101, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21254365

RESUMO

BACKGROUND: Caffeine intake is common during pregnancy, yet few epidemiologic studies have examined the association between maternal caffeine consumption and birth defects. Using data from the National Birth Defects Prevention Study (NBDPS), we examined the association between maternal caffeine consumption and anotia/microtia, esophageal atresia, small intestinal atresia, craniosynostosis, diaphragmatic hernia, omphalocele, and gastroschisis. METHODS: The NBDPS is a multi-site population-based case-control study. The present analysis included 3,346 case infants and 6,642 control infants born from October 1997 through December 2005. Maternal telephone interview reports of demographic characteristics and conditions and exposures before and during pregnancy were collected. Odds ratios and 95% confidence intervals, adjusted for relevant covariates, were calculated to estimate the associations between maternal dietary caffeine intake (coffee, tea, soda, and chocolate) and maternal use of caffeine-containing medications and each defect. RESULTS: We observed small, statistically significant elevations in adjusted odds ratios ranging from 1.3 to 1.8 for total maternal dietary caffeine intake or specific types of caffeinated beverages and anotia/microtia, esophageal atresia, small intestinal atresia, and craniosynostosis; however, dose-response patterns were absent. Periconceptional use of caffeine-containing medications was infrequent and estimates were imprecise. CONCLUSIONS: We did not find convincing evidence of an association between maternal caffeine intake and the birth defects included in this study. The increasing popularity of caffeine-containing energy drinks and other caffeinated products may result in higher caffeine intake among women of childbearing age. Future studies should consider more detailed evaluation of such products.


Assuntos
Cafeína/administração & dosagem , Craniossinostoses/epidemiologia , Dieta , Anormalidades do Sistema Digestório/epidemiologia , Adolescente , Adulto , Estudos de Casos e Controles , Anormalidades Congênitas/epidemiologia , Microtia Congênita , Demografia , Orelha/anormalidades , Atresia Esofágica/epidemiologia , Feminino , Humanos , Lactente , Recém-Nascido , Entrevistas como Assunto , Atresia Intestinal/epidemiologia , Masculino , Razão de Chances , Gravidez , Risco
12.
J Agromedicine ; 15(4): 357-62, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20954031

RESUMO

Commercial fishing has high rates of work-related injury and death and needs preventive strategies. Work-related fatal and nonfatal injury rates for New Jersey (NJ) commercial fishermen who suffered unintentional traumatic injuries from 2001 to 2007 are calculated using data from the United States Coast Guard (USCG) Marine Safety and Pollution Database and estimated denominator data. Fatalities were compared to those ascertained by the NJ Fatality Assessment Control and Evaluation (FACE) surveillance system. For the study years, 225 nonfatal injuries and 31 fatal injuries were reported. Among nonfatal injuries, the causes by frequency were fall onto surface, crushed between objects, struck by moving object, line handling/caught in lines, collision with fixed objects, fall into water, and other noncontact injuries. The distribution of fatal injuries differed, with the most frequent cause as crushed between objects. Falls into water and several noncontact injuries accounted for most of the other fatalities. The large majority (96%) of nonfatal injuries were contact injuries, whereas only 68% of fatalities were classified as contact. The overall incidence rate of nonfatal injuries was 1188 per 100,000 full-time equivalents (FTEs) per year. The rate varied considerably by year, from a low of 286 per 100,000 FTEs in 2001 and 2007 to 3806 per 100,000 FTEs in 2003. The overall occupational fatality rate over the period 2001-2007 was 164 per 100,000 FTEs per year. These results can aid in targeting the commercial fishing industry for injury prevention strategies and interventions, especially for falls, crushing injuries, and drownings.


Assuntos
Acidentes de Trabalho/estatística & dados numéricos , Pesqueiros/estatística & dados numéricos , Militares/estatística & dados numéricos , Saúde Ocupacional/estatística & dados numéricos , Ferimentos e Lesões/epidemiologia , Acidentes por Quedas/estatística & dados numéricos , Queimaduras/epidemiologia , Síndrome de Esmagamento/epidemiologia , Humanos , Incidência , New Jersey/epidemiologia , Fatores de Risco
13.
AAOHN J ; 58(9): 367-80, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20839728

RESUMO

Through school-sponsored career and technical education programs in New Jersey, students work part-time during or after school in paid and unpaid structured learning experiences regulated by the New Jersey Department of Education. Schools submit information on "reportable incidents," injury or illness resulting in physician treatment. Incidents including reported use of personal protective equipment (PPE) were assessed; 1,600 incident reports (1999 to 2008) were received. Attributes such as type and severity, body parts affected, and PPE use for incidents occurring at school among students grades 9 to 12 or labeled as "adults" during school hours (n = 285) were analyzed. Older teens incurred more injuries. PPE use was consistently low across age and gender. Students most frequently experienced knife injuries involving fingers and hands. Results identified potential injury determinants and training and intervention topics such as PPE, and support development of an enhanced reporting form.


Assuntos
Acidentes de Trabalho/estatística & dados numéricos , Equipamentos de Proteção/estatística & dados numéricos , Gestão de Riscos/organização & administração , Estudantes , Educação Vocacional , Ferimentos e Lesões/epidemiologia , Acidentes de Trabalho/legislação & jurisprudência , Acidentes de Trabalho/prevenção & controle , Adolescente , Distribuição por Idade , Causalidade , Emprego/legislação & jurisprudência , Emprego/estatística & dados numéricos , Feminino , Humanos , Incidência , Escala de Gravidade do Ferimento , Masculino , New Jersey/epidemiologia , Saúde Ocupacional/legislação & jurisprudência , Saúde Ocupacional/estatística & dados numéricos , Enfermagem do Trabalho , Vigilância da População , Distribuição por Sexo , Estudantes/estatística & dados numéricos , Educação Vocacional/organização & administração , Ferimentos e Lesões/etiologia , Ferimentos e Lesões/prevenção & controle
14.
Birth Defects Res A Clin Mol Teratol ; 88(4): 205-15, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20146378

RESUMO

BACKGROUND: Evidence links exposure to ambient air pollution during pregnancy, particularly gaseous pollutants and particulate matter, to an increased risk of adverse reproductive outcomes though the results for birth defects have been inconsistent. METHODS: We compared estimated exposure to ambient air pollutants during early pregnancy among mothers of children with oral cleft defects (cases) to that among mothers of controls, adjusting for available risk factors from birth certificates. We obtained ambient air pollutant data from air monitoring sites in New Jersey for carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O3), sulfur dioxide (SO(2)), particulate matter <10 microm in aerodynamic diameter (PM10) and particulate matter <2.5 microm in aerodynamic diameter (PM2.5). We used values from the nearest monitor (within 40 km of the residence at birth) for controls, cleft lip with or without cleft palate (CLP) and cleft palate only (CPO). RESULTS: Based on logistic regression analyses for each contaminant and all contaminants together, there were no consistent elevated associations between selected air pollutants and cleft malformations. Quartile of CO concentration showed a consistent protective association with CPO (p < 0.01). For other contaminants, confidence intervals (95%) of the odds ratios for some quartiles excluded one. CLP showed limited evidence of an association with increasing SO(2) exposure while CPO showed weak associations with increasing O3 exposure. CONCLUSION: There was little consistent evidence associating cleft malformations with maternal exposure to ambient air pollutants. Evaluating particular pollutants or disease subgroups would require more detailed measurement of exposure and classification of cleft defects.


Assuntos
Poluentes Atmosféricos/efeitos adversos , Fenda Labial/induzido quimicamente , Fissura Palatina/induzido quimicamente , Exposição Ambiental , Exposição Materna/efeitos adversos , Adolescente , Adulto , Consumo de Bebidas Alcoólicas/epidemiologia , Monóxido de Carbono/efeitos adversos , Estudos de Casos e Controles , Fenda Labial/epidemiologia , Fissura Palatina/epidemiologia , Monitoramento Ambiental , Monitoramento Epidemiológico , Feminino , Humanos , Recém-Nascido , Masculino , Pessoa de Meia-Idade , New Jersey/epidemiologia , Dióxido de Nitrogênio/efeitos adversos , Ozônio/efeitos adversos , Material Particulado/efeitos adversos , Gravidez , Fumar/epidemiologia , Dióxido de Enxofre/efeitos adversos , Adulto Jovem
15.
Paediatr Perinat Epidemiol ; 18(5): 352-60, 2004 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15367322

RESUMO

Congenital cardiovascular malformations (CCM) cause substantial neonatal morbidity and mortality. Known risk factors for CCM explain only 10-20% of all cases. Few studies have examined mothers' physical exposures during pregnancy and the risk of CCM in their offspring. This study examined the association between exposures to extreme temperatures, prolonged standing, and heavy lifting during early pregnancy and risk of CCM in offspring. Using a case-control study design, 502 cases and 1066 controls were drawn from the population of all liveborn infants born between January 1988 and June 1991 to mothers living in 14 counties in New York State. Cases were identified from a population-based registry of congenital malformations. Controls were randomly selected from birth certificate records. Interviews were conducted by telephone, using a structured questionnaire. Exposure estimates were based on women's self-reports of conditions in the residence and workplace. Eighty-three per cent of the mothers were white, and 66% were between 25 and 34 years old. After adjusting all results for known risk factors and confounding variables, we found no significant increased risk of CCM in subjects whose mothers reported being exposed during early pregnancy to extreme heat (OR = 1.13, 95% CI 0.59, 2.19), nor to extreme cold (OR = 1.19, 95% CI 0.66, 2.15). Mothers who reported ever using a hot tub, hot bath, or sauna during early pregnancy had no increased risk of CCM in their offspring (OR = 0.88, 95% CI 0.65, 1.18). Performing heavy lifting during early pregnancy did not increase the risk of CCM in offspring (OR = 0.80, 95% CI 0.57, 1.11). Prolonged standing during early pregnancy was not associated with an increased risk of CCM in children (OR = 1.03, 95% CI 0.82, 1.28). Thus if these maternal exposures have an adverse effect, it is unlikely to involve CCMs.


Assuntos
Anormalidades Cardiovasculares/embriologia , Efeitos Tardios da Exposição Pré-Natal , Adulto , Estudos de Casos e Controles , Temperatura Baixa/efeitos adversos , Feminino , Temperatura Alta/efeitos adversos , Humanos , Recém-Nascido , Remoção/efeitos adversos , Exposição Materna/efeitos adversos , Razão de Chances , Gravidez , Fatores de Risco
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