1.
BMJ Open Gastroenterol
; 4(1): e000127, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28243458
RESUMO
Inflammatory bowel disease is frequently associated with spondylarthritis (SpA). It has been discussed that α4/ß7 expressing lymphocytes are involved in the aetiology of SpA. We report a case of a successful combination therapy of vedolizumab (VDZ) and etanercept (ETA) in a patient with ulcerative colitis with pouchitis and SpA. In our case VDZ was effective for pouchitis and ineffective for SpA. The combination with ETA might be a useful treatment strategy to control both diseases and first indications suggest that it is safe. α4/ß7 Expressing lymphocytes are most likely not associated in the aetiology of SpA.