Papillary thyroid carcinoma metastasis to the pituitary: A case report.

Pituitary metastases (PM) from differentiated thyroid carcinoma (DTC) are rare. Various case series and case reports in the past suggest that symptoms of PM from DTC correspond to parasellar lesions that affect adjacent nerves, rather than intrasellar lesions that cause endocrinologic disorders such as diabetes insipidus. This case report describes the occurrence of PM in a patient with a history of papillary thyroid carcinoma that had previously recurred in cervical lymph nodes. The relevant literature is reviewed, and a discussion of the salient points of the case is provided.

Subperiosteal Hematoma of the Orbit: A Variety of Presentations.

Subperiosteal hematoma of the orbit is an uncommon radiologic finding. Most typically, the hemorrhage is in the superior aspect of the orbit, however, location within the orbit may vary. Subperiosteal hematoma of the orbit may be associated with trauma. Nontraumatic etiology has also been well documented. We present a series of three cases, to illustrate typical and atypical radiologic findings of subperiosteal hematoma of the orbit, both traumatic and nontraumatic. Review of the pertinent radiologic literature and its relation to the cases presented here is also provided.

Laryngeal examination in thyroid and parathyroid surgery: An American Head and Neck Society consensus statement: AHNS Consensus Statement.

This American Head and Neck Society (AHNS) consensus statement discusses the techniques of laryngeal examination for patients undergoing thyroidectomy and parathyroidectomy. It is intended to help guide all clinicians who diagnose or manage adult patients with thyroid disease for whom surgery is indicated, contemplated, or has been performed. This consensus statement concludes that flexible transnasal laryngoscopy is the optimal laryngeal examination technique, with other techniques including laryngeal ultrasound and stroboscopy being useful in selected scenarios. © 2016 Wiley Periodicals, Inc. Head Neck 38: 811-819, 2016.

Epithelioid Hemangioendothelioma of the Maxillary Sinus.

The clinical course and pathologic features of a 72 year old female who presented with epistaxis are presented. Radiographic findings were notable for a large, soft tissue lesion filling the maxillary sinus with significant bony erosion and expansion. The patient was ultimately diagnosed with epithelioid hemangioendothelioma (EHE) and underwent endoscopic resection. She has no evidence of local, regional or distant recurrence 14 months post-surgery. The rarity of this neoplasm, the unusual anatomic location and non-specific symptoms present diagnostic and management challenges. Epithelioid vascular tumors encompass a spectrum of benign and malignant tumors. EHE itself is thought to have an intermediate malignant behavior pattern, though cases with indolent behavior have been reported. Differentiation of EHE from other lesions has historically based on histopathology. Additionally, recent studies have described a recurrent genetic fusion WWTR1-CAMTA1 in EHE, involving t(1;3) (p36;q25). This represents the second reported case of EHE arising in a paranasal sinus. The histopathologic findings of this lesion are reviewed.

Orbital imaging: a pattern-based approach.

Providing a concise and relevant differential diagnosis for clinicians who order imaging studies can be difficult for the interpreting radiologist. In evaluation of cross-sectional imaging studies of the orbit, the myriad disease processes that occur in the orbit have overlapping features both clinically and at imaging. Disease entities can be categorized into a small set of relatively distinct patterns. In conjunction with careful consideration of the clinical history, a pattern-based approach to the interpretation of cross-sectional imaging studies of the orbit can help the radiologist provide a list of possible causes for the computed tomography and magnetic resonance imaging findings.

Case 206: persistent hypertrophic primary vitreous.

History This patient was a 20-month-old full-term girl who had not received any routine pediatric care. During a physical examination, left-sided leukocoria was detected. Subsequently, a left-sided cataract was diagnosed. The patient was sent for magnetic resonance (MR) imaging of the brain and orbits.

Masticator space: imaging anatomy for diagnosis.

Masticator space anatomy and pathologic conditions are illustrated examples from computed tomography and magnetic resonance imaging. Characteristic imaging features of various disease processes are presented to aid the otolaryngologist (head and neck surgeon) in diagnosis. The article describes infection, primary neoplasm, metastatic disease, Osteonecrosis, and vascular anomalies.

Baseline, one and three month changes in the peripapillary retinal nerve fiber layer in acute optic neuritis: relation to baseline vision and MRI.

OBJECTIVE: Retinal nerve fiber layer (RNFL) loss occurs with MS or after optic neuritis. Acute RNFL alterations at presentation and changes over time have not been well documented. We analyzed regional RNFL changes using 2 methods, ocular coherence tomography (OCT) and scanning laser polarimetry (SLP), to study initial edema and early RNFL loss. METHODS: 40 subjects with unilateral acute optic neuritis, had prospective OCT and SLP RNFL thickness values organized into 4 quadrants. We compared affected with normal fellow and control eyes to determine RNFL thickening (≥ 10% of 95th percentile of controls) and thinning (≥ 10µ less than fellow eye) at presentation, 1 and 3 months. RESULTS: RNFL thickening occurred in 27/33 eyes (82%) by OCT and in 21/34 eyes (62%) by SLP at baseline. At 1 month, RNFL thickening was common even as thinning developed in 15/23 (65%) of eyes by OCT and in 15/28 eyes (54%) by SLP. At 3 months, RNL was thinned by OCT in 14/24 (58%) and by SLP in 15/25 (60%) affected eyes (58%). Neither MRI optic nerve lesion nor vision at baseline correlated with optical image findings or vision outcome. CONCLUSIONS: RNFL swelling, most likely due to axoplasmic stasis from blockade at the lesion site in optic neuritis, is seen with OCT better than SLP. RNFL swelling in some quadrants and loss in others occur at 1 month and is well seen with interocular comparison by both methods. Optical imaging provides pathophysiologic as well as quantitative information regarding axonal changes.

Kikuchi-fujimoto disease with bilateral uveitis.

Kikuchi-Fujimoto disease (KFD), also called histiocytic necrotizing lymphadenitis, is rare condition that usually presents with lymphadenitis and fever. KFD has been associated with many infectious disease processes, predominantly viral. Association with systemic inflammatory processes has been described. Here we present a case of KFD with the rare ocular manifestation of bilateral anterior uveitis, and corresponding findings on magnetic resonance imaging (MRI).

Extraspinal findings on lumbar spine MR imaging.

Interpretation of radiologic studies requires vigilance on the part of the radiologist to identify findings and abnormalities outside the region of interest. In the case of routine lumbar spine MRI for low back pain, many extraspinal abnormalities can often be identified. Some of these findings may account for low back pain. Other findings are incidental, but may have significant clinical implications, and are important to recognize. We present twenty-four examples of incidental findings from lumbar spine MRI examinations. The findings involve various organ systems, covering a broad range of clinical urgency.

Sclerosis of the pterygoid process in untreated patients with nasopharyngeal carcinoma.

PURPOSE: To retrospectively evaluate the prevalence of pterygoid process sclerosis in patients with untreated nasopharyngeal carcinoma. MATERIALS AND METHODS: This retrospective HIPAA-compliant study was performed after the institutional review board deemed it to be exempt from review and patient informed consent. Contrast material-enhanced computed tomographic (CT) scans of the neck obtained in 31 patients (22 men, nine women; mean age, 42 years; age range, 27-68 years) with untreated nasopharyngeal carcinoma and in 31 control subjects (17 men, 14 women; mean age, 43 years; age range, 19-62 years) were evaluated independently by two neuroradiologists. The presence of sclerosis of the pterygoid process-defined as increased attenuation in the medullary cavity and/or thickening of the cortical bone-was assessed. Other findings noted included pterygoid process erosion, enhancing tumor adjacent to the pterygoid process, and CT evidence of parapharyngeal extension of the tumor. The data were evaluated by using generalized estimating equations based on a binary logistic regression model. RESULTS: The prevalence of pterygoid process sclerosis averaged for the two readers was 60% (37 of 62 subjects) among the patients with nasopharyngeal carcinoma but only 3% (two of 62 subjects) among the control subjects, indicating a highly significantly increased prevalence (P < .001) of this finding in the patients with nasopharyngeal carcinoma. The overall prevalences of pterygoid process erosion, parapharyngeal extension of tumor, and enhancing tumor adjacent to the pterygoid process were 27% (17 of 62 subjects), 47% (29 of 62 subjects), and 77% (48 of 62 subjects), respectively. Pterygoid process sclerosis was the sole skull base abnormality in 36% (11 of 31) of the patients with nasopharyngeal carcinoma. CONCLUSION: Sclerosis of the pterygoid process, which was present in about half of the patients with untreated nasopharyngeal carcinoma, may reflect tumor proximity to or tumor invasion of the pterygoid process.

Conventional MR imaging with simultaneous measurements of cerebral blood volume and vascular permeability in ganglioglioma.

The conventional MR imaging appearance of gangliogliomas is often variable and nonspecific. Conventional MR images, relative cerebral blood volume (rCBV) and vascular permeability (K(trans)) measurements were reviewed in 20 patients with pathologically proven grade 1 and 2 gangliogliomas (n = 20) and compared to a group of grade 2 low-grade gliomas (n = 30). The conventional MRI findings demonstrated an average lesion size of 4.1 cm, contrast enhancement (n = 19), variable degree of edema, variable mass effect, necrosis/cystic areas (n = 8), well defined (n = 12), signal heterogeneity (n = 9), calcification (n = 4). The mean rCBV was 3.66 +/- 2.20 (mean +/- std) for grade 1 and 2 gangliogliomas. The mean rCBV in a comparative group of low-grade gliomas (n = 30), was 2.14 +/- 1.67. p Value < 0.05 compared with grade 1 and 2 ganglioglioma. The mean K(trans) was 0.0018 +/- 0.0035. The mean K(trans) in a comparative group of low-grade gliomas (n = 30), was 0.0005 +/- 0.001. p Value = 0.14 compared with grade 1 and 2 ganglioglioma. The rCBV measurements of grade 1 and 2 gangliogliomas are elevated compared with other low-grade gliomas. The K(trans), however, did not demonstrate a significant difference. Gangliogliomas demonstrate higher cerebral blood volume compared with other low-grade gliomas, but the degree of vascular permeability in gangliogliomas is similar to other low-grade gliomas. Higher cerebral blood volume measurements can help differentiate gangliogliomas from other low-grade gliomas.