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1.
J Fr Ophtalmol ; 47(9): 104297, 2024 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-39341041

RESUMO

INTRODUCTION: Solitary fibrous tumor (SFT) is a rare borderline mesenchymal tumor typically arising in the pleura and involving the orbit as its most common extra-pleural location. CASE DESCRIPTION: We herein describe two cases of orbital SFT arising in both a 69-year-old woman presenting with progressive proptosis of the left eye and a 49-year-old woman presenting with binocular diplopia. The diagnoses relied on histopathological analysis of biopsy samples. Because of the poor local prognosis, we decided to perform an orbital exenteration in the first case. In the second case, a complete resection surgery was performed. CONCLUSION: SFT presents classics histological features and immunohistochemical markers that are essential to the diagnosis. SFT is classified as a benign tumor, but in some cases, it can show aggressive behavior with the potential for local tissue invasion and, more scarcely, distant metastasis. This is why complete resection remains the treatment of choice for SFT.

3.
J Fr Ophtalmol ; 41(9): 830-835, 2018 Nov.
Artigo em Francês | MEDLINE | ID: mdl-30343989

RESUMO

PURPOSE: To report cases of patients with severe bilateral corneal blindness and recurrent refractory perforation to keratoplasty and conventional treatment, for whom Boston keratoprosthesis (KP) was a satisfactory alternative when combined with a temporalis aponeurosis graft. DESCRIPTION OF CASES: The first patient had progressive Lyell syndrome with spontaneous corneal perforation. The second had a severe graft vs. host reaction with a persistent Seidel-positive descemetocele. Despite repeated penetrating keratoplasties, amniotic membrane (AM) transplantations, and buccal mucosal (BM) grafts, they both experienced recurrent corneal perforation. The only solution thus appeared to be Boston Type I KP surgery. One month postoperatively, the first patient had to receive a temporalis aponeurosis (TA) graft, due to thinning of the recipient graft. Six months postoperatively, his visual acuity (VA) was 1/10 without correction, and the corneal status had been stabilized. The second patient underwent KP and TA graft concurrently. Six months after surgery, VA was 2/10 uncorrected, and the local inflammation had been stabilized. OBSERVATION: Boston type I keratoprostheses constitute an alternative in cases of severe bilateral corneal blindness with perforation refractory to conventional treatment and surgery, with satisfactory visual results. DISCUSSION: Patients with preoperative severe ocular surface disease are at greater risk of postoperative keratolysis. For our patients with a higher risk, TA graft prevented corneal melt. TA seems to be more effective than AM or BM in preventing corneal thinning or melt. CONCLUSION: We would recommend performing a TA graft in combination with Boston KP surgery concurrently as first line treatment in eyes with severe ocular surface inflammation.


Assuntos
Aponeurose/cirurgia , Aponeurose/transplante , Perfuração da Córnea/cirurgia , Ceratoplastia Penetrante/métodos , Próteses e Implantes , Implantação de Prótese/métodos , Cegueira/etiologia , Cegueira/cirurgia , Perfuração da Córnea/etiologia , Neoplasias Oculares/secundário , Neoplasias Oculares/cirurgia , Humanos , Ceratoplastia Penetrante/efeitos adversos , Leucemia Mieloide Aguda/patologia , Leucemia Mieloide Aguda/cirurgia , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Implantação de Prótese/efeitos adversos , Síndrome de Stevens-Johnson/complicações , Síndrome de Stevens-Johnson/cirurgia
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