1.
Chem Commun (Camb)
; 60(45): 5844-5847, 2024 May 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38752317
RESUMO
Native mass spectrometric analysis of TPR2A and GrpE with unpurified peptides derived from limited proteolysis of their respective PPI partners (HSP90 C-terminus and DnaK) facilitated efficient, qualitative identification of interfacial epitopes involved in transient PPI formation. Application of this approach can assist in elucidating interfaces of currently uncharacterised transient PPIs.