Assuntos
Mitologia , Escultura , Anoftalmia , Grécia Antiga , História Antiga , Fotografação , Escultura/históriaRESUMO
A retinal pigment epithelial (RPE) tear is a well-known complication of retinal pigment epithelial detachments (PED) and may cause a significant visual impairment. The most common cause is a vascularized PED in patients with exudative age-related macular degeneration (AMD). The development of diagnostic imaging techniques brings us closer to the etiology and pathophysiological mechanisms of this entity, offering us new strategies for treatment and follow-up. The advent of intravitreal antiangiogenic treatment (anti-VEGF) has led to an increase in the number of reported cases of RPE tears, which are an important vision-limiting factor during treatment. However, RPE tears may occur spontaneously or as a consequence of thermal laser treatment, photodynamic therapy or anti-VEGF therapy. It is accepted that the mechanism of RPE tears is multifactorial. The optimization of the functional outcome of this complication has been described with continuous treatment with antiangiogenic drugs. The goal of the present review is to evaluate the incidence, risk factors and treatment of RPE tears.
Assuntos
Perfurações Retinianas , Epitélio Pigmentado da Retina/lesões , Diagnóstico por Imagem/métodos , Humanos , Descolamento Retiniano/complicações , Descolamento Retiniano/diagnóstico , Descolamento Retiniano/epidemiologia , Descolamento Retiniano/terapia , Perfurações Retinianas/diagnóstico , Perfurações Retinianas/epidemiologia , Perfurações Retinianas/etiologia , Perfurações Retinianas/terapia , Epitélio Pigmentado da Retina/diagnóstico por imagem , Epitélio Pigmentado da Retina/cirurgia , Fatores de Risco , Ruptura Espontânea/diagnóstico , Ruptura Espontânea/epidemiologia , Ruptura Espontânea/etiologia , Ruptura Espontânea/terapiaRESUMO
PURPOSE: To describe the anatomical and functional results of intravitreal antiangiogenic treatment in optic nerve head drusen associated with choroidal neovascularisation. CASE REPORT: An 8 year-old male patient with a diagnosis of neovascular membrane in the right eye associated with bilateral optic nerve head drusen. Best-corrected visual acuity (BCVA) was by counting fingers in the right eye and improved to 0.4 after antiangiogenic treatment. A complete consolidation of the lesion was observed with no associated complications arising from the treatment. DISCUSSION/CONCLUSIONS: Antiangiogenic treatment is an effective option, and no side-effects have been observed in treatment of neovascular tissue associated with optic disc drusen in children.
Assuntos
Inibidores da Angiogênese/uso terapêutico , Bevacizumab/uso terapêutico , Neovascularização de Coroide/tratamento farmacológico , Drusas do Disco Óptico/complicações , Criança , Neovascularização de Coroide/etiologia , Fibrose , Humanos , Injeções Intravítreas , Masculino , Papiledema/etiologia , Indução de Remissão , Hemorragia Retiniana/etiologia , Líquido Sub-Retiniano , Tomografia de Coerência ÓpticaAssuntos
Segmento Anterior do Olho/diagnóstico por imagem , Glaucoma de Ângulo Fechado/cirurgia , Iris/cirurgia , Lasers de Gás/uso terapêutico , Fotocoagulação/métodos , Tomografia de Coerência Óptica , Feminino , Glaucoma de Ângulo Fechado/diagnóstico por imagem , Humanos , Iris/diagnóstico por imagemRESUMO
Dysthyroid optic neuropathy (DON) is one of the complications that can affect Graves' orbitopathy (GO) patients. Its prevalence is estimated at less than 5%. It is usually treated with intravenous steroids, radiotherapy or orbital decompression. Tocilizumab has been proposed as a treatment option in cases of GO refractory to steroid treatment, with good clinical results. Our aim is to report the case of a patient with optic neuropathy secondary to GO treated with tocilizumab as primary treatment option.