Advances in power driven pocket/root instrumentation.

OBJECTIVES: The primary aim was: "Does power-driven pocket/root instrumentation offer a clinical advantage over hand instrumentation"? Secondary aim was to update knowledge base of power-driven instrumentation post Tunkel et al. (2002). MATERIAL AND METHODS: A literature search of power-driven instruments (in vitro, in vivo and controlled clinical trials) was performed from April 2001 using similar criteria to Tunkel et al. (2002). Primary outcome was whether power-driven instruments offered an advantage over hand instrumentation; secondary outcomes were effect on root surface, effectiveness of new instrument designs, and role of biophysical effects such as cavitation. RESULTS: From a total of 41 studies, 14 studies involved comparison of power-driven devices with hand instrumentation for non-surgical therapy. These were subdivided into new designs of power instrumentation, full-mouth debridement and irrigation and patient acceptance. Use of power-driven instrumentation provides similar clinical outcomes compared with hand instrumentation. Difficulty of pooling studies continues to hinder the drawing of definitive conclusions. CONCLUSION: Newer designs of powered instruments have not shown any benefit when compared with other ultrasonic devices in non-surgical periodontal therapy. New in vitro research shows there is variation in the performance of different tip designs and generators, but its clinical relevance remains unknown.

Spectroscopically distinct sites present in methyltrioxorhenium grafted onto silica-alumina, and their abilities to initiate olefin metathesis.

Deposition of CH3ReO3 onto the surface of dehydrated, amorphous silica-alumina generates a highly active, supported catalyst for the metathesis of olefins. However, silica-alumina with a high (10 wt %) Re loading is no more active than silica-alumina with low (1 wt %) loading, while CH3ReO3 on silica is completely inactive. Catalysts prepared by grafting CH3ReO3 on silica-alumina contain two types of spectroscopically distinct sites. The more strongly bound sites are responsible for olefin metathesis activity and are formed preferentially at low Re loadings (< or =1 wt %). They are created by two Lewis acid/base interactions: (1) the coordination of an oxo ligand to an Al center of the support and (2) interaction of one of the adjacent bridging oxygens (AlOSi) with the Re center. At higher Re loadings (1-10 wt %), CH3ReO3 also interacts with surface silanols by H-bonding. This gives rise to highly mobile sites, most of which can be observed by 13C solid-state NMR even without magic-angle spinning. Their formation can be prevented by capping the surface hydroxyl groups with hexamethyldisilazane prior to grafting CH3ReO3, resulting in a metathesis catalyst that is more selective, more robust, and more efficient in terms of Re use.

Stress-induced changes in human salivary alpha-amylase activity -- associations with adrenergic activity.

The salivary enzyme alpha-amylase has been proposed to indicate stress-reactive bodily changes. A previous study by the authors revealed marked increases in salivary alpha-amylase following psychosocial stress, indicating a stress-dependent activation of salivary alpha-amylase. Salivary alpha-amylase has been suggested to reflect catecholaminergic reactivity. Our aim was to assess/evaluate a possible relationship between salivary alpha-amylase and adrenergic parameters, i.e. catecholamines, as well as other stress markers. Using an intra-individual repeated measures design, 30 healthy young men underwent the Trier Social Stress Test (TSST), which consists of a mental arithmetic task and free speech in front of an audience and a control condition in randomized order. Salivary alpha-amylase and salivary cortisol as well as plasma catecholamines and cardiovascular activity were repeatedly measured before, during, and after both conditions. Significant differences were found between the stress and the rest condition in salivary alpha-amylase, salivary cortisol, plasma catecholamines, and cardiovascular parameters (heart rate, LF, HF, LF/HF). However, general alpha-amylase responses (area under the curve) were not associated with general responses in catecholamines and cortisol in the stress condition (r smaller than 0.25 for all analyses). Analysis of cardiovascular parameters indicates a positive relationship between amylase and sympathetic tone (LF/HF) during stress. Salivary alpha-amylase is sensitive to psychosocial stress. Since it does not seem to be closely related to other biological stress markers such as catecholamines and cortisol, salivary alpha-amylase may be a useful additional parameter for the measurement of stress.