Energetic study of the disordered solvent in the crystal structure of an isoxazole derivative. Erratum.

An error in printing is reported. In the paper by Pani et al. [Acta Cryst. (1998), B54, 872-876] the value of Deltarho(max) is given incorrectly in the last sentence on page 874. The sentence should read 'In the last difference Fourier map, the highest Deltarho values were found near the Cl atoms (Deltarho(max) +0.32 e Å(-3)); the final reliability indexes were R(1) = 0.072 over 1762 F(o) > 4sigma(F(o)) and wR(2) = 0.228 on 4029 F(o)(2) for 245 refined parameters, with a goodness-of-fit of 0.96.'

Relationships between mutagenic potency, reversion mechanism and metabolic behaviour within a class of chemicals (hydrazine derivatives).

Homogeneous mutagenicity data, available for 16 hydrazine derivatives assayed in the Salmonella/microsome test, were tentatively associated with their chemical structure. Some possible relationships were detected between chemical features and the following parameters in vitro: (a) mutagenic potency, expressed as revertants per micromole compound, which varied over a 3200-fold range without S-9 mix and a 7000-fold range with S-9 mix; (b) reversion mechanism, as inferred from the selective sensitivity of 5 Salmonella typhimurium tester strains; (c) metabolic behaviour in the presence of S-9 mix containing rat liver, mouse liver or mouse lung /-9 fractions from animals treated with Aroclor-1254.