Higher incidence of new atrial fibrillation in hospitalised COVID-19 patients compared to lower respiratory tract infection, however, less patients prescribed anticoagulants at discharge.

Infection contributes to developing cardiac arrhythmias, such as atrial fibrillation (AF), which causes over 25% of ischaemic stroke. We analysed a hospital coding database of patients hospitalised with Coronavirus 2019 (COVID-19) ± AF or a lower respiratory tract infection (LRTI) ± AF, to compare the incidence of first-diagnosed or 'new' AF (nAF) between COVID-19 and LRTI, as well as risk factors associated with developing nAF during COVID-19. In total, 2,243 patients with LRTI and 488 patients with COVID-19 were included. nAF was diagnosed in significantly more patients with COVID-19 compared with those with LRTI (7.0% vs 3.6%, p=0.003); however, significantly fewer patients with COVID-19 were discharged on anticoagulation medication (26.3% vs 56.4%, p=0.02). Patients who developed nAF during COVID-19 were older (p<0.001), had congestive cardiac failure (p=0.004), ischaemic heart disease (IHD) or peripheral vascular disease (PVD) (p<0.001) and a higher CHA2DS2-VASc score (p=0.02), compared with patients with COVID-19 patients who did not develop nAF. Older age (Odds ratio (OR) 1.03, p=0.007) and IHD/PVD (OR 2.87, p=0.01) increased the odds of developing nAF with COVID-19.

Hearables, in-ear sensing devices for bio-signal acquisition: a narrative review.

INTRODUCTION: Hearables are ear devices used for multiple purposes including ubiquitous/remote monitoring of vital signals. This can support early detection, prevention, and management of urgent/non-urgent healthcare needs. This review therefore seeks to analyze the challenges and capabilities of hearables used to monitor human physiological signals. AREAS COVERED: Studies were identified via search (Medline, Embase, Web of Science, Cochrane Library, Scopus) and conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Bias assessment used the Mixed Methods Appraisal Tool 2018 and Quality Assessment of Diagnostic Accuracy Studies 2nd Edition. 92/631 studies met the inclusion criteria and were qualitatively analyzed. The outcomes, applications, advantages, and limitations were discussed according to the vital signal measured. The bias risk ranged from low to high, with most studies facing moderate-to-high risk in subject selection due to small sample sizes. EXPERT OPINION: Most studies reported good outcomes for ear signal acquisition compared to reference devices. To improve practicability and implementation, wireless connectivity, battery life, impact of motion/environmental artifacts and comfort need to be addressed going forward. Hearable technologies have also shown potential synergies with hearing aids. In future, multimodal ear-sensing devices opens the possibility of comprehensive health monitoring within daily life.