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1.
Sci Rep ; 13(1): 22821, 2023 Dec 20.
Artigo em Inglês | MEDLINE | ID: mdl-38129479

RESUMO

This study analyzes the influence of the Pacific-Japan (PJ) atmospheric teleconnection pattern and its interaction with oceanic processes on sea surface warming over the Northwestern Pacific. The PJ pattern is a thermally driven Rossby wave that originates over the tropical western Pacific through deep convection and propagates toward high latitudes. It plays a significant role in sea surface warming by inducing anticyclonic circulation and the corresponding northwestward extension of the subtropical high over the Northwestern Pacific. This study revealed that the key processes responsible for sea surface warming were an increase in insolation and a decrease in the ocean-to-atmosphere latent heat flux under the anticyclonic conditions driven by the PJ. This finding provides valuable insights into the role of atmospheric processes, we refer to it as the "atmospheric pathway", in the development of East Asian marine heatwaves (MHWs). A detailed understanding of this process will contribute to the prediction and mitigation of MHWs in East Asian countries.

2.
Environ Pollut ; 290: 118051, 2021 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-34461414

RESUMO

In this study, we investigated the daily variability of PM10 concentrations in January in Korea during the past 19 years (2001-2019), as well as the associated atmospheric circulation patterns. The daily PM10 concentrations were classified into three cases: low (L; < 50 µg/m3), high (H; 50-100 µg/m3), and extremely high (EH; ≥ 100 µg/m3). We found that the strength of the East Asian winter monsoon influenced the PM10 variability in the L and H cases. However, the EH cases were strongly influenced by the rapid growth of barotropic warming (anticyclonic anomaly) over the eastern North Atlantic and Northern Europe (ENE), and the stationary Rossby waves grew rapidly over Eurasia within only four days. Analysis of the quasi-geostrophic geopotential tendency budget revealed that the anticyclonic anomaly over the ENE was enhanced by vorticity advection. Linear baroclinic model experiments confirmed that vorticity forcing over the ENE induces favorable atmospheric conditions for the occurrence of EH PM10 events in East Asia. As a result, the PM10 concentration sharply increased sharply by approximately three times over four days. This study suggests that understanding atmospheric teleconnections between the ENE and East Asia can effectively predict the occurrence of EH PM10 events in Korea, helping to reduce the human health risks from atmospheric pollution.


Assuntos
Poluentes Atmosféricos , Material Particulado , Poluentes Atmosféricos/análise , Europa (Continente) , Humanos , Material Particulado/análise , República da Coreia , Estações do Ano
4.
Tissue Eng ; 12(2): 209-19, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16548680

RESUMO

The osteogenic potential of AAV5hBMP6 was compared with that of ADhBMP6 in immunodeficient and immunocompetent rats. AAV5hBMP6 (2.3 x 10(12) particles) and ADhBMP6 (5 x 10(7) PFU) elicited viral antibody production in immunocompetent rats. Among rats that received AAV5hBMP6, the earliest time points at which the bone was visible under CT scanner were 30 days in 2-month-old Sprague-Dawley (SD) rats and 60 days in 18-month-old SD rats. The mean volumes of ectopic bone 90 days after viral injection were 0.31 +/- 0.14 cm(3) in athymic nude rats, 0.64 +/- 0.12 cm(3) in 2-month-old SD rats, and 0.21 +/- 0.10 cm(3) in 18-month-old SD rats. In contrast, among rats that received ADhBMP6, the earliest time points to observe the bone formation by CT scan were 15 days in 2-month-old rats and no bone formation in 18-month-old SD rats. The mean volumes of ectopic bone were 4.17 +/- 0.05 cm(3) in athymic nude rats and 0.06 +/- 0.03 cm(3) in 2-month-old SD rats. Although both types of viruses induced an immune response in immunocompetent animals, this response played different roles in the process of bone formation induced by the BMP6 vectors.


Assuntos
Adenoviridae/genética , Proteínas Morfogenéticas Ósseas/farmacologia , Dependovirus/genética , Osteogênese/fisiologia , Animais , Proteína Morfogenética Óssea 6 , Proteínas Morfogenéticas Ósseas/administração & dosagem , Linfócitos T CD4-Positivos/metabolismo , Linfócitos T CD8-Positivos/metabolismo , Vetores Genéticos , Humanos , Músculo Esquelético/citologia , Osteogênese/efeitos dos fármacos , Ratos , Ratos Nus , Ratos Sprague-Dawley , Proteínas Recombinantes/administração & dosagem , Proteínas Recombinantes/farmacologia , Especificidade da Espécie , Fatores de Tempo , Tomografia por Raios X
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