Morphology of the spinal nerves from the cervical segments of the spinal cord of the African giant rat (Cricetomys Gambianus).

This study provides detailed description of the gross morphology and distribution of the nerves arising from the cervical segments of the spinal cord of the African Giant Rat (AGR). Two (2) AGRs were used for this study. The rats were euthanized using halothane. The skin and superficial fascia were removed, and dissection of the muscles in the cervical region and thoracic limbs was carried out. The vertebral canal was opened by means of a rongeur. Eight (8) pairs of spinal nerves (C1-C8) arose from the cervical segments of the spinal cord of the AGR by means of dorsal and ventral roots which merged lateral to the spinal cord to form spinal nerves. Each cervical spinal nerve divided into a dorsal and ventral ramus just before exiting the intervertebral foramen. The dorsal rami divided into medial and lateral branches distributed on the medial faces of the semispinalis and splenius muscles, respectively. The ventral rami of C1, C2 and a branch from C3 interconnected to form the cervical plexus from which branches were distributed to the M. cleidomstoideus, M. cleidooccipitalis, M. occipitoscapularis, M. omotransversarius and M. trapezius. The ventral rami of C5, C6, C7, C8 and T1 (first thoracic spinal nerve) interconnected to form the brachial plexus. The cervical spinal nerves gave rise to dorsal rami or primary branches that supplied the skin and muscles of the dorsal part of the neck and the ventral primary branches which interconnected to give rise to the cervical plexus and brachial plexuses of the AGR.

Calcaneal pitch and lateral talocalcaneal angle among nigerians / Inclinación calcáneo y ángulo talocalcáneo lateral en nigerianos

Various papers in the fields of Radiology, orthopaedics and radiographic anatomy have employed the use of angles measured on X-rays to make diagnoses, select treatment modalities in the management of foot disorders as well as predicting the outcome of interventions to these disorders. Calcaneal pitch (CP) and lateral talocalcaneal angle (L TCA) are angles that can be drawn on lateral standing radiographs of the foot and are used widely in the diagnosis, prognosis and choice of treatment modalities for various disorders of the foot. Data on these important radiological tools are lacking in Nigeria. Hence, the study is an attempt to bridge this gap. Using a hinge goniometer, the angles were measured from normal lateral standing radiographs of the foot. Mean CP was found to be 15.08 +/- 2.87 (n=63) and the mean L TCA was found to be 38.85°+/-8.20° (n=130). Differences in the means of the angles seen between the sexes were not statistically significant (CP, p=0.70; L TCA, p=0.60). No such significant difference was also observed in mean of the angles with respect to the sides of the body (CP, p=0.58; L TCA, p=0.13) or between ethnic groups (CP, p=0.30; L TCA, p=0.40).

Diversos trabajos en las áreas de la radiología, ortopedia y anatomía radiográfica han empleado los ángulos medidos en las radiografías para hacer diagnósticos, seleccionar las modalidades de tratamiento en el manejo de los trastornos del pie, así como para predecir el resultado de las intervenciones para estos trastornos. La inclinación calcánea (PC) y el ángulo talocalcáneo lateral (L TCA) son los ángulos que se pueden extraer desde las radiografías laterales de los pies y ser utilizados ampliamente en el diagnóstico, pronóstico y elección de modalidades de tratamiento para diversos trastornos del pie. Los datos sobre estos importantes instrumentos radiológicos no existen en Nigeria, y su estudio es un intento de obtener esta información. Usando un goniómetro bisagra, los ángulos se midieron a partir de radiografías normales permanentes lateral del pie. La media de CP se fue 15,08+/-2,87 (n = 63) y la media de TCA L fue 38,85°+/-8,20° (n = 130). Las diferencias en las medias de los ángulos observados entre los sexos no fueron estadísticamente significativas (CP, p = 0,70; L TCA, p = 0,60). No hubo diferencias significativas en la media de los ángulos con respecto al lado (CP, p = 0,58; L TCA, p = 0,13) o entre grupos étnicos (CP, p = 0,30; L TCA, p = 0,40).

Vitamin E protects Wistar rats from chlorpyrifos-induced increase in erythrocyte osmotic fragility.

The aim of the present study was to evaluate the effect of chronic chlorpyrifos (CPF) exposure on erythrocyte osmotic fragility, the role of lipid peroxidation and the ameliorative effect of vitamin E on the erythrocyte fragility. Twenty young adult male Wistar rats divided into four groups of five animals each served as subjects for this study. Groups I (control) and II were exposed to soya oil (2 ml/kg) and vitamin E (75 mg/kg), respectively. Rats in group III were exposed to CPF (10.6 mg/kg 1/8th of the previously determined LD50 of 85 mg/kg over a period of 48 h), while those in group IV were pretreated with vitamin E (75 mg/kg) and then exposed to CPF, 30 min later. The regimens were administered orally by gavage once daily for a period of 17 weeks. Blood samples collected at the end of the test period were analyzed for erythrocyte osmotic fragility, while the washed erythrocytes were used to evaluate malondialdehyde (MDA) concentration, as an index of lipid peroxidation. The study showed that repeated CPF exposure caused increased erythrocyte fragility and MDA concentration. Pretreatment with vitamin E ameliorated CPF-induced increase in erythrocyte fragility and lipoperoxidative changes in Wistar rats.