Predicting nonlinear multi-pulse propagation in optical fibers via a lightweight convolutional neural network.

The nonlinear evolution of ultrashort pulses in optical fiber has broad applications, but the computational burden of convolutional numerical solutions necessitates rapid modeling methods. Here, a lightweight convolutional neural network is designed to characterize nonlinear multi-pulse propagation in highly nonlinear fiber. With the proposed network, we achieve the forward mapping of multi-pulse propagation using the initial multi-pulse temporal profile as well as the inverse mapping of the initial multi-pulse based on the propagated multi-pulse with the coexistence of group velocity dispersion and self-phase modulation. A multi-pulse comprising various Gaussian pulses in 4-level pulse amplitude modulation is utilized to simulate the evolution of a complex random multi-pulse and investigate the prediction precision of two tasks. The results obtained from the unlearned testing sets demonstrate excellent generalization and prediction performance, with a maximum absolute error of 0.026 and 0.01 in the forward and inverse mapping, respectively. The approach provides considerable potential for modeling and predicting the evolution of an arbitrary complex multi-pulse.

A biomimetic design for efficient petrochemical spill disposal: CoFe-PBA modified superhydrophobic melamine sponge with mechanical/chemical durability and low fire risk.

Due to frequent petrochemical spills, environmental pollution and the threat of secondary marine fires have arisen, necessitating an urgent need for petrochemical spill treatment strategies with high-performance oil-water separation capabilities. To address the challenges of poor durability, instability in hydrophobic conditions, and difficulty in absorbing high-viscosity crude oil associated with hydrophobic absorbent materials, the authors of this study took inspiration from the unique micro and nanostructures of springtails' water-repellent skin. We engineered a superhydrophobic melamine sponge using interfacial assembly techniques designated as Si@PBA@PDA@MS. This material demonstrated improved mechanical and chemical durability, enhanced photothermal performance, and reduced fire risk. The metal-organic framework (MOF)-derived cobalt-iron Prussian blue analog (CoFe-PBA) was firmly anchored to the sponge framework by the chelation of cobalt ions using polydopamine (PDA). The results demonstrated that Si@PBA@PDA@MS demonstrated excellent superhydrophobicity (WCA=163.5°) and oil absorption capacity (53.4-97.5 g/g), maintaining high durability even after 20 cycles of absorption-squeezing. Additionally, it could still exhibit excellent mechanical properties, hydrophobic stability, and absorption performance across a wide temperature range (0-100 °C), pH range (1-14), and high compression strength (ε = 80%), with excellent mechanical/chemical durability. Furthermore, Si@PBA@PDA@MS demonstrated remarkable photothermal performance and low fire risk, offering efficient, safe, and sustainable practical value for effective petrochemical spill treatment.

A High-Efficient DOPO-Based Flame Retardant as a Co-Curing Agent for Simultaneously Enhancing the Fire Safety and Mechanical Properties of Epoxy Resin.

Simultaneously enhancing the fire safety and mechanical properties of epoxy resin (EP) remains a persistent challenge. Herein, a high-efficient phosphaphenanthrene-based flame retardant (FNP) is synthesized using 3,5-diamino-1,2,4-triazole, 4-formylbenzoic acid, and 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide. Due to the presence of active amine groups, FNP is employed as a co-curing agent for fabricating EP composites with outstanding fire safety and mechanical properties. EP containing 8 wt% FNP (EP/8FNP) achieves a vertical burning (UL-94) V-0 rating with a limiting oxygen index of 31%. Meanwhile, FNP declines the peak heat release rate, total heat release, and total smoke release of EP/8FNP by 41.1%, 31.8%, and 16.0%, respectively, compared to those of unmodified EP. The increased fire safety of EP/FNP composites is because FNP promotes the formation of an intumescent, compact, and cross-linking char layer for EP/FNP composites, and releases P-containing substances and noncombustible gases in the gas phase during combustion. In addition, EP/8FNP exhibits 20.3% and 5.4% increase in the flexural strength and modulus compared with those of pure EP. Furthermore, FNP enhances the glass transition temperature of EP/FNP composites from 141.6 °C for pure EP to 147.3 °C for EP/8FNP. Therefore, this work is conducive to the future development of fabricating fire-safe EP composites with enhanced mechanical properties.

Organic Phosphoric Acid Doped Polyaniline-Coupled g-C3 N4 for Enhancing Fire Safety of Intumescent Flame-Retardant Epoxy Resin.

Two kinds of polyaniline coupled graphitized carbon nitride nanosheets doped with different organic phosphoric acids (CP@PA, with phytic acid; CP@NP, with amino trimethyl phosphonic acid) are developed by in-situ polymerization. According to the analysis of the section morphology and element distribution of epoxy resin (EP) composites, although CP@PA and CP@NP show completely different morphology, they can significantly enhance the dispersion of graphitized carbon nitride nanosheets in EP. Moreover, the different oxidation states of phosphorus contained in the CP@PA and CP@NP lead to varying effects on the fire safety of EP. The flame retardancy Index (FRI) is a dimensionless index to evaluate the performance of flame retardants. When used as a flame retardant, CP@NP (FRI = 3.22) is better than CP@PA (FRI = 1.29) in flame retardant, especially in suppressing thermal hazards. As a synergist of intumescent flame retardants (IFR), CP@PA (FRI = 26.12) is most effective in improving the comprehensive fire safety property of EP and achieves an "Excellent" rating. Therefore, two different flame-retardant mechanisms of CP@PA and CP@NP are summarized by analyzing the combustion behavior and changes of condensed phase. In summary, this research may be helpful to the design of nano synergies for IFR systems.

Resveratrol protects against postmenopausal atherosclerosis progression through reducing PCSK9 expression via the regulation of the ERα-mediated signaling pathway.

Elevated circulating proprotein convertase subtilisin/kexin 9 (PCSK9) levels are an important contributor to postmenopausal atherosclerosis (AS). We have previously reported that resveratrol (RSV), as a phytoestrogen, reduces hepatocyte steatosis and PCSK9 expression in L02 cells. This study aimed to investigate how RSV reduces PCSK9 expression to inhibit postmenopausal AS progression. Here, we found that treatment of Ovx/ApoE -/- mice with RSV significantly reduced dyslipidemia, plasma PCSK9 concentration and aortic plaque area. In addition, RSV significantly inhibited liver fat accumulation and improved the hepatocyte ultrastructure. Further studies showed that RSV upregulated estrogen receptor α (ERα) expression, while reduced the liver X receptor α (LXRα) expression and sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity. In vitro, RSV inhibited insulin-induced elevated intracellular/extracellular PCSK9 levels, enhanced receptor-mediated uptake of low-density lipoproteins in HepG2 cells. Furthermore, RSV attenuated the activity of the SRE-dependent PCSK9 promoter. However, these effects can be partially reversed by the antiestrogen ICI 182,780. Attenuation of these changes with ERα inhibition suggest that RSV may prevent the progression of postmenopausal AS by reducing PCSK9 expression in hepatocytes through ERα-mediated signaling.

Co-curing preparation of flame retardant and smoke-suppressive epoxy resin with a novel phosphorus-containing ionic liquid.

Phosphorus-containing ionic liquid derivatives have been proven to be effective flame retardants for epoxy resin (EP). Flame retardants can accelerate the curing process and improve flame retardancy and smoke suppression of EP composites, which is challenging. In this paper, a novel phosphorus-containing ionic liquid (TPP-PF6) was synthesized and used both as a co-curing agent with 4,4'-diaminodiphenylmethane (DDM) and as a highly effective flame retardant for EP. It has been found that TPP-PF6 was conducive to improve the char formation of EP to inhibit the smoke release at high temperatures. For EP/TPP-PF6 composites, the flame-retardant performance was enhanced rapidly with the increase of TPP-PF6. With only 2 wt% of TPP-PF6, EP/2.0TPP-PF6 reached a UL-94 V-0 rating and a limiting oxygen index of 30.3%. The peak heat release rate, total heat release, and total smoke production values of EP/2.0TPP-PF6 were reduced by 36.32%, 45.81%, and 15.1% compared with those of pure EP, respectively. The thermal degradation products and flame retardant mechanism in gas and condensed phases were studied. It was found that TPP-PF6 had flame retardant effect in the barrier effect of the condensed phase and the quenching effect of the gas phase. This work explores the high-efficiency flame retardant and smoke-suppressive structures with co-curing properties for EP, thus promoting the wide application of EP materials.

Cocktail Formula and Application Prospects for Oral and Maxillofacial Organoids.

Oral and maxillofacial organoids (OMOs), tiny tissues and organs derived from stem cells cultured through 3-d cell culture models, can fully summarize the cell tissue structure, physiological functions and biological characteristics of the source tissues in the body. OMOs are applied in areas such as disease modelling, developmental and regenerative medicine, drug screening, personalized treatment, etc. Although the construction of organoids in various parts of the oral and maxillofacial (OM) region has achieved considerable success, the existing cocktail formulae (construction strategies) are not widely applicable for tissues of various sources due to factors including the heterogeneity of the source tissues and the dependence on laboratory technology. Most of their formulae are based on growth factor niches containing expensive recombinant proteins with their efficiency remaining to be improved. In view of this, the cocktail formulae of various parts of the OM organs are reviewed with further discussion of the application and prospects for those OMOs to find some affordable cocktail formula with strong operability and high repeatability for various maxillofacial organs. The results may help improve the efficiency of organoid construction in the laboratory and accelerate the pace of the clinical use of organoid technology.

Maximum bandwidth of a composite achromatic quartz half-wave plate.

To investigate the characteristics of the achromatic bandwidth of composite achromatic quartz half-wave plates (QHWPs), three kinds of multi-element achromatic QHWPs with central wavelengths at 1000-3000 nm and relative deviation of the maximum phase retardation (Δδmax) of 1%-5% are discussed. Based on the particle swarm optimization algorithm, the maximum bandwidth of the composite achromatic QHWPs at room temperature is obtained. The results show that the achromatic bandwidth increases with Δδmax. At the same Δδmax, the achromatic bandwidth of four-element achromatic QHWPs is larger than that of two- and three-element achromatic QHWPs. The maximum achromatic bandwidth of four-element achromatic QHWPs can reach 2229 nm when Δδmax is 5%. In addition, the temperature effect on bandwidth in the wavelength range of 300-1500 nm is analyzed, and the maximum bandwidth of temperature insensitive composite achromatic QHWPs is 840 nm. The results provide a great reference for designing achromatic wave plates with broad bandwidths.

Composite achromatic quartz wave plate with adjustable retardation and temperature insensitivity.

In order to obtain a composite achromatic wave plate with adjustable retardation, temperature insensitivity, and achromatic bandwidth of 500 nm, a five-element composite achromatic quartz wave plate is designed based on particle swarm optimization. The total phase retardation can be adjusted by rotating the azimuth angle of the central wave plate. The results show that the total phase retardation is adjustable with the range of 90°-180° when the range of temperature and the achromatic wavelength is -20-80∘C and 750-1250 nm, respectively. The absolute value of the relative deviation of the maximum phase retardation is less than 3.6%, which meets the design requirements of the wave plate. The temperature insensitivity of the five-element wave plate is better than the three- and four-element wave plates. This method is of great reference value for designing this kind of composite achromatic wave plate.