1.
Chem Commun (Camb)
; 51(6): 1112-5, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25461278
RESUMO
3-Aryltetrahydrobenzisoxazoles prepared en route to the coleophomone natural products and analogues, were found to undergo a remarkable base-mediated rearrangement to 2-aryltetrahydrobenzoxazoles. The scope of this unprecedented, facile transformation was probed: a range of analogues was produced, a mechanism proposed, and an application demonstrated by synthesis of a known herbicidal compound.
Assuntos
Isoxazóis/química , Oxazóis/química , Cristalografia por Raios X , Compostos Heterocíclicos de 4 ou mais Anéis/química , Estrutura Molecular
2.
Chem Commun (Camb)
; (3): 228-9, 2002 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12120378
RESUMO
Building block methodology from trifluoroethanol and ring-closing metathesis using a Fürstner modification of Grubbs' conditions allows the rapid synthesis of novel difluorinated cyclooctenones.