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Behav Brain Sci ; 47: e83, 2024 May 13.
Artigo em Inglês | MEDLINE | ID: mdl-38738353

RESUMO

Reductionist methodologies reduce phenomena to some of their lower-level components. Researchers gradually shift their focus away from observing the actual object of study toward investigating and optimizing such lower-level proxies. Following reductionism, these proxies progressively diverge further from the original object of study. We vividly illustrate this in the evolution of target-based drug discovery from rational and phenotypic drug discovery.


Assuntos
Descoberta de Drogas , Neurociências , Descoberta de Drogas/métodos , Humanos , Neurociências/métodos
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